Synthesis of 11C-dl-tryptophan and its purification using high-pressure liquid chromatography
Publication
, Journal Article
Zalutsky, MR; Wu, J; Harper, PV; Wickland, T
Published in: The International Journal Of Applied Radiation And Isotopes
January 1, 1981
Carbon-11-dl-tryptophan has been produced from 11C-cyanide using a modified Bücherer-Strecker technique for synthesis and a high-pressure liquid chromatographic system for purification. More than 80 preparations have been run with an average radiochemical yield of 50% and synthesis and purification times of about 28 min. These modifications have significantly increased the level of 11C-tryptophan activity which is available for clinical use per mCi of 11C-cyanide. © 1981.
Duke Scholars
Published In
The International Journal Of Applied Radiation And Isotopes
DOI
ISSN
0020-708X
Publication Date
January 1, 1981
Volume
32
Issue
3
Start / End Page
182 / 184
Citation
APA
Chicago
ICMJE
MLA
NLM
Zalutsky, M. R., Wu, J., Harper, P. V., & Wickland, T. (1981). Synthesis of 11C-dl-tryptophan and its purification using high-pressure liquid chromatography. The International Journal Of Applied Radiation And Isotopes, 32(3), 182–184. https://doi.org/10.1016/0020-708X(81)90114-9
Zalutsky, M. R., J. Wu, P. V. Harper, and T. Wickland. “Synthesis of 11C-dl-tryptophan and its purification using high-pressure liquid chromatography.” The International Journal Of Applied Radiation And Isotopes 32, no. 3 (January 1, 1981): 182–84. https://doi.org/10.1016/0020-708X(81)90114-9.
Zalutsky MR, Wu J, Harper PV, Wickland T. Synthesis of 11C-dl-tryptophan and its purification using high-pressure liquid chromatography. The International Journal Of Applied Radiation And Isotopes. 1981 Jan 1;32(3):182–4.
Zalutsky, M. R., et al. “Synthesis of 11C-dl-tryptophan and its purification using high-pressure liquid chromatography.” The International Journal Of Applied Radiation And Isotopes, vol. 32, no. 3, Jan. 1981, pp. 182–84. Scopus, doi:10.1016/0020-708X(81)90114-9.
Zalutsky MR, Wu J, Harper PV, Wickland T. Synthesis of 11C-dl-tryptophan and its purification using high-pressure liquid chromatography. The International Journal Of Applied Radiation And Isotopes. 1981 Jan 1;32(3):182–184.
Published In
The International Journal Of Applied Radiation And Isotopes
DOI
ISSN
0020-708X
Publication Date
January 1, 1981
Volume
32
Issue
3
Start / End Page
182 / 184