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Pulsating tandem microbubble for localized and directional single-cell membrane poration.

Publication ,  Journal Article
Sankin, GN; Yuan, F; Zhong, P
Published in: Physical review letters
August 2010

The interaction of laser-generated tandem microbubble (maximum diameter of about 50  μm) with single (rat mammary carcinoma) cells is investigated in a 25-μm liquid layer. Antiphase and coupled oscillation of the tandem microbubble leads to the formation of alternating, directional microjets (with max microstreaming velocity of 10  m/s) and vortices (max vorticity of 350 000  s{-1}) in opposite directions. Localized and directional membrane poration (200 nm to 2  μm in pore size) can be produced by the tandem microbubble in an orientation and proximity-dependent manner, which is absent from a single oscillating microbubble of comparable size and at the same stand-off distance.

Duke Scholars

Published In

Physical review letters

DOI

EISSN

1079-7114

ISSN

0031-9007

Publication Date

August 2010

Volume

105

Issue

7

Start / End Page

078101

Related Subject Headings

  • Rats
  • Porosity
  • Molecular Imaging
  • Microscopy
  • Microbubbles
  • Hydrodynamics
  • General Physics
  • Cell Membrane
  • Cell Line, Tumor
  • Biological Transport
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Sankin, G. N., Yuan, F., & Zhong, P. (2010). Pulsating tandem microbubble for localized and directional single-cell membrane poration. Physical Review Letters, 105(7), 078101. https://doi.org/10.1103/physrevlett.105.078101
Sankin, G. N., F. Yuan, and P. Zhong. “Pulsating tandem microbubble for localized and directional single-cell membrane poration.Physical Review Letters 105, no. 7 (August 2010): 078101. https://doi.org/10.1103/physrevlett.105.078101.
Sankin GN, Yuan F, Zhong P. Pulsating tandem microbubble for localized and directional single-cell membrane poration. Physical review letters. 2010 Aug;105(7):078101.
Sankin, G. N., et al. “Pulsating tandem microbubble for localized and directional single-cell membrane poration.Physical Review Letters, vol. 105, no. 7, Aug. 2010, p. 078101. Epmc, doi:10.1103/physrevlett.105.078101.
Sankin GN, Yuan F, Zhong P. Pulsating tandem microbubble for localized and directional single-cell membrane poration. Physical review letters. 2010 Aug;105(7):078101.

Published In

Physical review letters

DOI

EISSN

1079-7114

ISSN

0031-9007

Publication Date

August 2010

Volume

105

Issue

7

Start / End Page

078101

Related Subject Headings

  • Rats
  • Porosity
  • Molecular Imaging
  • Microscopy
  • Microbubbles
  • Hydrodynamics
  • General Physics
  • Cell Membrane
  • Cell Line, Tumor
  • Biological Transport