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Caspases: an ancient cellular sword of Damocles.

Journal articles  - Journal Article, Review
Boyce, M; Degterev, A; Yuan, J
Published in: Cell Death Differ
January 2004
Published version (DOI) Open Access Copy (Duke) Link to item

Caspases are a family of cysteine proteases homologous to the Caenorhabditis elegans programmed cell death gene product CED-3. Caspases and their distant relatives, meta- and paracaspases, have been found in phylogenetically distant nonmetazoan groups, including plants, fungi and prokaryotes. This review summarizes the current information on the mechanisms and functions of non-mammalian caspases and their relatives in apoptotic and nonapoptotic processes, and explores the possible evolutionary origin of the caspase family.

Duke Scholars

Michael Scott Boyce
Author Michael Scott Boyce Biochemistry
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Published In

Cell Death Differ

DOI

10.1038/sj.cdd.4401339

ISSN

1350-9047

Publication Date

January 2004

Volume

11

Issue

1

Start / End Page

29 / 37

Location

England

Related Subject Headings

  • Humans
  • Evolution, Molecular
  • Caspases
  • Caenorhabditis elegans Proteins
  • Biochemistry & Molecular Biology
  • Apoptosis
  • Animals
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
 

Citation

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Boyce, M., Degterev, A., & Yuan, J. (2004). Caspases: an ancient cellular sword of Damocles. Cell Death Differ, 11(1), 29–37. https://doi.org/10.1038/sj.cdd.4401339
Boyce, M., A. Degterev, and J. Yuan. “Caspases: an ancient cellular sword of Damocles.” Cell Death Differ 11, no. 1 (January 2004): 29–37. https://doi.org/10.1038/sj.cdd.4401339.
Boyce M, Degterev A, Yuan J. Caspases: an ancient cellular sword of Damocles. Cell Death Differ. 2004 Jan;11(1):29–37.
Boyce, M., et al. “Caspases: an ancient cellular sword of Damocles.” Cell Death Differ, vol. 11, no. 1, Jan. 2004, pp. 29–37. Pubmed, doi:10.1038/sj.cdd.4401339.
Boyce M, Degterev A, Yuan J. Caspases: an ancient cellular sword of Damocles. Cell Death Differ. 2004 Jan;11(1):29–37.

Published In

Cell Death Differ

DOI

10.1038/sj.cdd.4401339

ISSN

1350-9047

Publication Date

January 2004

Volume

11

Issue

1

Start / End Page

29 / 37

Location

England

Related Subject Headings

  • Humans
  • Evolution, Molecular
  • Caspases
  • Caenorhabditis elegans Proteins
  • Biochemistry & Molecular Biology
  • Apoptosis
  • Animals
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences