Lipid modifications of G proteins.
Publication
, Journal Article
Casey, PJ
Published in: Curr Opin Cell Biol
April 1994
Covalent attachment of lipids is a near-universal mechanism through which eukaryotic cells direct and, in some cases, control membrane localization of G proteins. Studies conducted over the past year have substantially advanced our understanding of both the molecular mechanisms and the functional consequences of these modifications. Of particular note are the processes of palmitoylation of the alpha-subunits of heterotrimeric G proteins, and prenylation of members of the Ras superfamily of monomeric G proteins, where recent findings point to unexpected roles for lipid modifications in signaling through these proteins.
Duke Scholars
Published In
Curr Opin Cell Biol
DOI
ISSN
0955-0674
Publication Date
April 1994
Volume
6
Issue
2
Start / End Page
219 / 225
Location
England
Related Subject Headings
- Protein Processing, Post-Translational
- Protein Prenylation
- Palmitic Acids
- Palmitic Acid
- Myristic Acids
- Myristic Acid
- Molecular Sequence Data
- Humans
- GTP-Binding Proteins
- Fatty Acids
Citation
APA
Chicago
ICMJE
MLA
NLM
Casey, P. J. (1994). Lipid modifications of G proteins. Curr Opin Cell Biol, 6(2), 219–225. https://doi.org/10.1016/0955-0674(94)90139-2
Casey, P. J. “Lipid modifications of G proteins.” Curr Opin Cell Biol 6, no. 2 (April 1994): 219–25. https://doi.org/10.1016/0955-0674(94)90139-2.
Casey PJ. Lipid modifications of G proteins. Curr Opin Cell Biol. 1994 Apr;6(2):219–25.
Casey, P. J. “Lipid modifications of G proteins.” Curr Opin Cell Biol, vol. 6, no. 2, Apr. 1994, pp. 219–25. Pubmed, doi:10.1016/0955-0674(94)90139-2.
Casey PJ. Lipid modifications of G proteins. Curr Opin Cell Biol. 1994 Apr;6(2):219–225.
Published In
Curr Opin Cell Biol
DOI
ISSN
0955-0674
Publication Date
April 1994
Volume
6
Issue
2
Start / End Page
219 / 225
Location
England
Related Subject Headings
- Protein Processing, Post-Translational
- Protein Prenylation
- Palmitic Acids
- Palmitic Acid
- Myristic Acids
- Myristic Acid
- Molecular Sequence Data
- Humans
- GTP-Binding Proteins
- Fatty Acids