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Regional differences in awareness and attitudes regarding genetic testing for disease risk and ancestry.

Publication ,  Journal Article
Jonassaint, CR; Santos, ER; Glover, CM; Payne, PW; Fasaye, G-A; Oji-Njideka, N; Hooker, S; Hernandez, W; Foster, MW; Kittles, RA; Royal, CD
Published in: Human genetics
September 2010

Little is known about the lay public's awareness and attitudes concerning genetic testing and what factors influence their perspectives. The existing literature focuses mainly on ethnic and socioeconomic differences; however, here we focus on how awareness and attitudes regarding genetic testing differ by geographical regions in the US. We compared awareness and attitudes concerning genetic testing for disease risk and ancestry among 452 adults (41% Black and 67% female) in four major US cities, Norman, OK; Cincinnati, OH; Harlem, NY; and Washington, DC; prior to their participation in genetic ancestry testing. The OK participants reported more detail about their personal ancestries (p = 0.02) and valued ancestry testing over disease testing more than all other sites (p < 0.01). The NY participants were more likely than other sites to seek genetic testing for disease (p = 0.01) and to see benefit in finding out more about one's ancestry (p = 0.02), while the DC participants reported reading and hearing more about genetic testing for African ancestry than all other sites (p < 0.01). These site differences were not better accounted for by sex, age, education, self-reported ethnicity, religion, or previous experience with genetic testing/counseling. Regional differences in awareness and attitudes transcend traditional demographic predictors, such as ethnicity, age and education. Local sociocultural factors, more than ethnicity and socioeconomic status, may influence the public's awareness and belief systems, particularly with respect to genetics.

Duke Scholars

Published In

Human genetics

DOI

EISSN

1432-1203

ISSN

0340-6717

Publication Date

September 2010

Volume

128

Issue

3

Start / End Page

249 / 260

Related Subject Headings

  • Young Adult
  • United States
  • Socioeconomic Factors
  • Social Environment
  • Risk Factors
  • Middle Aged
  • Male
  • Humans
  • Health Knowledge, Attitudes, Practice
  • Genetics & Heredity
 

Citation

APA
Chicago
ICMJE
MLA
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Jonassaint, C. R., Santos, E. R., Glover, C. M., Payne, P. W., Fasaye, G.-A., Oji-Njideka, N., … Royal, C. D. (2010). Regional differences in awareness and attitudes regarding genetic testing for disease risk and ancestry. Human Genetics, 128(3), 249–260. https://doi.org/10.1007/s00439-010-0845-0
Jonassaint, Charles R., Eunice R. Santos, Crystal M. Glover, Perry W. Payne, Grace-Ann Fasaye, Nefertiti Oji-Njideka, Stanley Hooker, et al. “Regional differences in awareness and attitudes regarding genetic testing for disease risk and ancestry.Human Genetics 128, no. 3 (September 2010): 249–60. https://doi.org/10.1007/s00439-010-0845-0.
Jonassaint CR, Santos ER, Glover CM, Payne PW, Fasaye G-A, Oji-Njideka N, et al. Regional differences in awareness and attitudes regarding genetic testing for disease risk and ancestry. Human genetics. 2010 Sep;128(3):249–60.
Jonassaint, Charles R., et al. “Regional differences in awareness and attitudes regarding genetic testing for disease risk and ancestry.Human Genetics, vol. 128, no. 3, Sept. 2010, pp. 249–60. Epmc, doi:10.1007/s00439-010-0845-0.
Jonassaint CR, Santos ER, Glover CM, Payne PW, Fasaye G-A, Oji-Njideka N, Hooker S, Hernandez W, Foster MW, Kittles RA, Royal CD. Regional differences in awareness and attitudes regarding genetic testing for disease risk and ancestry. Human genetics. 2010 Sep;128(3):249–260.
Journal cover image

Published In

Human genetics

DOI

EISSN

1432-1203

ISSN

0340-6717

Publication Date

September 2010

Volume

128

Issue

3

Start / End Page

249 / 260

Related Subject Headings

  • Young Adult
  • United States
  • Socioeconomic Factors
  • Social Environment
  • Risk Factors
  • Middle Aged
  • Male
  • Humans
  • Health Knowledge, Attitudes, Practice
  • Genetics & Heredity