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Quantitative and qualitative preparations of bacterial outer membrane vesicles.

Publication ,  Journal Article
Chutkan, H; Macdonald, I; Manning, A; Kuehn, MJ
Published in: Methods Mol Biol
2013

Gram-negative bacterial outer membrane vesicle production and function have been studied using a variety of quantitative and qualitative methods. These types of analyses can be hampered by the use of impure vesicle preparations. Here we describe a set of techniques that are useful for the quantitative analysis of vesicle production and for preparative yields of highly purified vesicles for studies of vesicle function or composition. Procedures and advice are also included for the purification of vesicles from encapsulated and low-yield strains.

Duke Scholars

Published In

Methods Mol Biol

DOI

EISSN

1940-6029

Publication Date

2013

Volume

966

Start / End Page

259 / 272

Location

United States

Related Subject Headings

  • Microscopy, Electron
  • Gram-Negative Bacteria
  • Electrophoresis, Polyacrylamide Gel
  • Developmental Biology
  • Bacterial Outer Membrane Proteins
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0601 Biochemistry and Cell Biology
  • 0399 Other Chemical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Chutkan, H., Macdonald, I., Manning, A., & Kuehn, M. J. (2013). Quantitative and qualitative preparations of bacterial outer membrane vesicles. Methods Mol Biol, 966, 259–272. https://doi.org/10.1007/978-1-62703-245-2_16
Chutkan, Halima, Ian Macdonald, Andrew Manning, and Meta J. Kuehn. “Quantitative and qualitative preparations of bacterial outer membrane vesicles.Methods Mol Biol 966 (2013): 259–72. https://doi.org/10.1007/978-1-62703-245-2_16.
Chutkan H, Macdonald I, Manning A, Kuehn MJ. Quantitative and qualitative preparations of bacterial outer membrane vesicles. Methods Mol Biol. 2013;966:259–72.
Chutkan, Halima, et al. “Quantitative and qualitative preparations of bacterial outer membrane vesicles.Methods Mol Biol, vol. 966, 2013, pp. 259–72. Pubmed, doi:10.1007/978-1-62703-245-2_16.
Chutkan H, Macdonald I, Manning A, Kuehn MJ. Quantitative and qualitative preparations of bacterial outer membrane vesicles. Methods Mol Biol. 2013;966:259–272.

Published In

Methods Mol Biol

DOI

EISSN

1940-6029

Publication Date

2013

Volume

966

Start / End Page

259 / 272

Location

United States

Related Subject Headings

  • Microscopy, Electron
  • Gram-Negative Bacteria
  • Electrophoresis, Polyacrylamide Gel
  • Developmental Biology
  • Bacterial Outer Membrane Proteins
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0601 Biochemistry and Cell Biology
  • 0399 Other Chemical Sciences