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Symptom profiles of psychiatric disorders based on graded disease classes: an illustration using data from the WHO International Pilot Study of Schizophrenia.

Publication ,  Journal Article
Manton, KG; Korten, A; Woodbury, MA; Anker, M; Jablensky, A
Published in: Psychological medicine
February 1994

The Grade of Membership (GoM) model is a classification procedure which allows a person to be a member of more than one diagnostic class. It simultaneously quantifies the degrees of membership in classes while generating the discrete symptom profiles or 'pure types' describing classes. The model was applied to the symptomatology, history, and follow-up of 1065 cases in the WHO International Pilot Study of Schizophrenia. The model produced an eight diagnostic class or 'pure type' solution, of which five were related to the diagnostic concepts of schizophrenia and paranoid disorder, two types were affective disorders, and one asymptomatic type. A subtype of paranoid schizophreniform disorder found primarily in developing countries was identified. There was a strong association between pure types and the original clinical and computer generated (CATEGO) diagnoses. A GoM based psychiatric classification might more clearly identify core disease processes than conventional classification models by filtering the confounding effects of individual heterogeneity from pure type definitions.

Duke Scholars

Published In

Psychological medicine

DOI

EISSN

1469-8978

ISSN

0033-2917

Publication Date

February 1994

Volume

24

Issue

1

Start / End Page

133 / 144

Related Subject Headings

  • World Health Organization
  • Social Isolation
  • Schizophrenia
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Pilot Projects
  • Paranoid Disorders
  • Mood Disorders
  • Male
  • Humans
 

Citation

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Manton, K. G., Korten, A., Woodbury, M. A., Anker, M., & Jablensky, A. (1994). Symptom profiles of psychiatric disorders based on graded disease classes: an illustration using data from the WHO International Pilot Study of Schizophrenia. Psychological Medicine, 24(1), 133–144. https://doi.org/10.1017/s0033291700026908
Manton, K. G., A. Korten, M. A. Woodbury, M. Anker, and A. Jablensky. “Symptom profiles of psychiatric disorders based on graded disease classes: an illustration using data from the WHO International Pilot Study of Schizophrenia.Psychological Medicine 24, no. 1 (February 1994): 133–44. https://doi.org/10.1017/s0033291700026908.
Manton, K. G., et al. “Symptom profiles of psychiatric disorders based on graded disease classes: an illustration using data from the WHO International Pilot Study of Schizophrenia.Psychological Medicine, vol. 24, no. 1, Feb. 1994, pp. 133–44. Epmc, doi:10.1017/s0033291700026908.
Manton KG, Korten A, Woodbury MA, Anker M, Jablensky A. Symptom profiles of psychiatric disorders based on graded disease classes: an illustration using data from the WHO International Pilot Study of Schizophrenia. Psychological medicine. 1994 Feb;24(1):133–144.
Journal cover image

Published In

Psychological medicine

DOI

EISSN

1469-8978

ISSN

0033-2917

Publication Date

February 1994

Volume

24

Issue

1

Start / End Page

133 / 144

Related Subject Headings

  • World Health Organization
  • Social Isolation
  • Schizophrenia
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Pilot Projects
  • Paranoid Disorders
  • Mood Disorders
  • Male
  • Humans