Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel
Journal cover image

Keloids treated with excision followed by radiation therapy.

Publication ,  Journal Article
Klumpar, DI; Murray, JC; Anscher, M
Published in: J Am Acad Dermatol
August 1994

BACKGROUND: In the treatment of keloids surgical excision followed by radiation therapy provides the highest reported control rates of 72% to 92%. OBJECTIVE: We evaluated the effectiveness of excision followed by radiation therapy in the treatment of keloids and compared the efficacy of orthovoltage and electron beam radiation. METHODS: One hundred twenty-six keloids were treated with radiation therapy after surgical excision. Median follow-up period was 12 years. Recurrence rate, side effects, and effectiveness of therapy were assessed. Data were analyzed with multivariate analysis for significant objective and subjective factors. RESULTS: Higher posttreatment recurrence rates were noted with keloids forming at infected sites and in patients with a family history. No increased likelihood of recurrence was noted with respect to patient age, sex, or ethnicity; keloid size or location; individual keloid history; or prior therapy or radiation type used. CONCLUSION: Excision followed by radiation therapy is a useful and effective method of keloid eradication, particularly in cases in which lesions are disfiguring or refractory. Electron beam radiation offers no advantage over orthovoltage as a treatment.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J Am Acad Dermatol

DOI

ISSN

0190-9622

Publication Date

August 1994

Volume

31

Issue

2 Pt 1

Start / End Page

225 / 231

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Time Factors
  • Risk Factors
  • Retrospective Studies
  • Recurrence
  • Radiotherapy, High-Energy
  • Radiotherapy Dosage
  • Male
  • Keloid
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Klumpar, D. I., Murray, J. C., & Anscher, M. (1994). Keloids treated with excision followed by radiation therapy. J Am Acad Dermatol, 31(2 Pt 1), 225–231. https://doi.org/10.1016/s0190-9622(94)70152-0
Klumpar, D. I., J. C. Murray, and M. Anscher. “Keloids treated with excision followed by radiation therapy.J Am Acad Dermatol 31, no. 2 Pt 1 (August 1994): 225–31. https://doi.org/10.1016/s0190-9622(94)70152-0.
Klumpar DI, Murray JC, Anscher M. Keloids treated with excision followed by radiation therapy. J Am Acad Dermatol. 1994 Aug;31(2 Pt 1):225–31.
Klumpar, D. I., et al. “Keloids treated with excision followed by radiation therapy.J Am Acad Dermatol, vol. 31, no. 2 Pt 1, Aug. 1994, pp. 225–31. Pubmed, doi:10.1016/s0190-9622(94)70152-0.
Klumpar DI, Murray JC, Anscher M. Keloids treated with excision followed by radiation therapy. J Am Acad Dermatol. 1994 Aug;31(2 Pt 1):225–231.
Journal cover image

Published In

J Am Acad Dermatol

DOI

ISSN

0190-9622

Publication Date

August 1994

Volume

31

Issue

2 Pt 1

Start / End Page

225 / 231

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Time Factors
  • Risk Factors
  • Retrospective Studies
  • Recurrence
  • Radiotherapy, High-Energy
  • Radiotherapy Dosage
  • Male
  • Keloid
  • Humans