Skip to main content

Heal thyself: using endogenous regeneration to repair bone.

Publication ,  Journal Article
Alman, BA; Kelley, SP; Nam, D
Published in: Tissue Eng Part B Rev
December 2011

Bone has the capacity to repair itself after an injury, and this occurs in normal fracture repair. This reparative process can be harnessed to regenerate segments of bone using distraction osteogenesis, in which the healing bone is slowly stretched. The use of animal models is identifying the important sources of cells for this endogenous bone regeneration, signaling molecules that regulate this reparative process, and the environmental cues important for success bone regeneration. A more complete understanding of the cells and pathways involved in this process can be applied to improve the outcome of distraction osteogenesis and to the development of methods to enhance endogenous bone regeneration.

Duke Scholars

Published In

Tissue Eng Part B Rev

DOI

EISSN

1937-3376

Publication Date

December 2011

Volume

17

Issue

6

Start / End Page

431 / 436

Location

United States

Related Subject Headings

  • Wound Healing
  • Osteogenesis, Distraction
  • Osteoblasts
  • Humans
  • Fracture Healing
  • Bone and Bones
  • Bone Regeneration
  • Biomedical Engineering
  • Animals
  • 4003 Biomedical engineering
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Alman, B. A., Kelley, S. P., & Nam, D. (2011). Heal thyself: using endogenous regeneration to repair bone. Tissue Eng Part B Rev, 17(6), 431–436. https://doi.org/10.1089/ten.TEB.2011.0189
Alman, Benjamin A., Simon P. Kelley, and Diane Nam. “Heal thyself: using endogenous regeneration to repair bone.Tissue Eng Part B Rev 17, no. 6 (December 2011): 431–36. https://doi.org/10.1089/ten.TEB.2011.0189.
Alman BA, Kelley SP, Nam D. Heal thyself: using endogenous regeneration to repair bone. Tissue Eng Part B Rev. 2011 Dec;17(6):431–6.
Alman, Benjamin A., et al. “Heal thyself: using endogenous regeneration to repair bone.Tissue Eng Part B Rev, vol. 17, no. 6, Dec. 2011, pp. 431–36. Pubmed, doi:10.1089/ten.TEB.2011.0189.
Alman BA, Kelley SP, Nam D. Heal thyself: using endogenous regeneration to repair bone. Tissue Eng Part B Rev. 2011 Dec;17(6):431–436.

Published In

Tissue Eng Part B Rev

DOI

EISSN

1937-3376

Publication Date

December 2011

Volume

17

Issue

6

Start / End Page

431 / 436

Location

United States

Related Subject Headings

  • Wound Healing
  • Osteogenesis, Distraction
  • Osteoblasts
  • Humans
  • Fracture Healing
  • Bone and Bones
  • Bone Regeneration
  • Biomedical Engineering
  • Animals
  • 4003 Biomedical engineering