Scholars@Duke publication: Changes in serum lipids in patients with condylomata acuminata treated with interferon alfa-n1 (Wellferon).

Changes in serum lipids in patients with condylomata acuminata treated with interferon alfa-n1 (Wellferon).

Publication , Journal Article

Olsen, EA; Lichtenstein, GR; Wilkinson, WE

Published in: J Am Acad Dermatol

August 1988

Nine men with refractory condylomata acuminata were treated with intramuscular interferon alfa-n1 and the effect on their serum lipid levels was noted. Comparison of lipid panels before and after interferon revealed that all nine patients had an increase (median 62 mg/dl, p = 0.004) in their triglyceride level and a decrease (median 21 mg/dl, p = 0.004) in high-density lipoprotein cholesterol levels. Total cholesterol levels tended to decrease but the change was not statistically significant. This effect on serum lipids should be considered when interferon alfa-n1 is used in the treatment of genital warts.

Duke Scholars

Author Elise Arline Olsen Dermatology

Author William E. Wilkinson Biostatistics & Bioinformatics, Division of Biostatistics

Published In

J Am Acad Dermatol

DOI

10.1016/s0190-9622(88)70173-5

ISSN

0190-9622

Publication Date

August 1988

Volume

Issue

2 Pt 1

Start / End Page

286 / 289

Location

United States

Related Subject Headings

Triglycerides
Male
Interferon Type I
Humans
Dermatology & Venereal Diseases
Condylomata Acuminata
Cholesterol, VLDL
Cholesterol, LDL
Cholesterol, HDL
Cholesterol

Citation

APA

Chicago

ICMJE

MLA

NLM

Olsen, E. A., Lichtenstein, G. R., & Wilkinson, W. E. (1988). Changes in serum lipids in patients with condylomata acuminata treated with interferon alfa-n1 (Wellferon). J Am Acad Dermatol, 19(2 Pt 1), 286–289. https://doi.org/10.1016/s0190-9622(88)70173-5

Olsen, E. A., G. R. Lichtenstein, and W. E. Wilkinson. “Changes in serum lipids in patients with condylomata acuminata treated with interferon alfa-n1 (Wellferon).” J Am Acad Dermatol 19, no. 2 Pt 1 (August 1988): 286–89. https://doi.org/10.1016/s0190-9622(88)70173-5.

Olsen EA, Lichtenstein GR, Wilkinson WE. Changes in serum lipids in patients with condylomata acuminata treated with interferon alfa-n1 (Wellferon). J Am Acad Dermatol. 1988 Aug;19(2 Pt 1):286–9.

Olsen, E. A., et al. “Changes in serum lipids in patients with condylomata acuminata treated with interferon alfa-n1 (Wellferon).” J Am Acad Dermatol, vol. 19, no. 2 Pt 1, Aug. 1988, pp. 286–89. Pubmed, doi:10.1016/s0190-9622(88)70173-5.

Olsen EA, Lichtenstein GR, Wilkinson WE. Changes in serum lipids in patients with condylomata acuminata treated with interferon alfa-n1 (Wellferon). J Am Acad Dermatol. 1988 Aug;19(2 Pt 1):286–289.