Regional cerebral blood flow estimated by 133-xenon inhalation.
Publication
, Journal Article
Obrist, WD; Thompson, HK; Wang, HS; Wilkinson, WE
Published in: Stroke
1975
A method is described for estimating the clearance rate and fractional blood flow of the fast (gray matter) compartment of the brain from the first ten minutes of 122 XE clearance curves, following a one-minute inhalation. Computer-simulated data were used to test the adequacy of the two-compartmental model employed, and to evaluate the stability of the parameters in the presence of random noise. A comparison was made between this approach and the previously reported three-compartmental analysis. Regional cerbral blood flow data were obtained on 48 young control subjects and 20 elderly demented patients. Hemispheral, regional, and test-retest variations were determined, as well as differences between the groups.
Duke Scholars
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Published In
Stroke
DOI
ISSN
0039-2499
Publication Date
1975
Volume
6
Issue
3
Start / End Page
245 / 256
Location
United States
Related Subject Headings
- Xenon Isotopes
- Scintillation Counting
- Neurology & Neurosurgery
- Neurocognitive Disorders
- Models, Biological
- Methods
- Metabolic Clearance Rate
- Male
- Humans
- Female
Citation
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ICMJE
MLA
NLM
Obrist, W. D., Thompson, H. K., Wang, H. S., & Wilkinson, W. E. (1975). Regional cerebral blood flow estimated by 133-xenon inhalation. Stroke, 6(3), 245–256. https://doi.org/10.1161/01.str.6.3.245
Obrist, W. D., H. K. Thompson, H. S. Wang, and W. E. Wilkinson. “Regional cerebral blood flow estimated by 133-xenon inhalation.” Stroke 6, no. 3 (1975): 245–56. https://doi.org/10.1161/01.str.6.3.245.
Obrist WD, Thompson HK, Wang HS, Wilkinson WE. Regional cerebral blood flow estimated by 133-xenon inhalation. Stroke. 1975;6(3):245–56.
Obrist, W. D., et al. “Regional cerebral blood flow estimated by 133-xenon inhalation.” Stroke, vol. 6, no. 3, 1975, pp. 245–56. Pubmed, doi:10.1161/01.str.6.3.245.
Obrist WD, Thompson HK, Wang HS, Wilkinson WE. Regional cerebral blood flow estimated by 133-xenon inhalation. Stroke. 1975;6(3):245–256.
Published In
Stroke
DOI
ISSN
0039-2499
Publication Date
1975
Volume
6
Issue
3
Start / End Page
245 / 256
Location
United States
Related Subject Headings
- Xenon Isotopes
- Scintillation Counting
- Neurology & Neurosurgery
- Neurocognitive Disorders
- Models, Biological
- Methods
- Metabolic Clearance Rate
- Male
- Humans
- Female