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CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels?

Publication ,  Journal Article
van Rhoon, GC; Samaras, T; Yarmolenko, PS; Dewhirst, MW; Neufeld, E; Kuster, N
Published in: Eur Radiol
August 2013

OBJECTIVE: To define thresholds of safe local temperature increases for MR equipment that exposes patients to radiofrequency fields of high intensities for long duration. These MR systems induce heterogeneous energy absorption patterns inside the body and can create localised hotspots with a risk of overheating. METHODS: The MRI + EUREKA research consortium organised a "Thermal Workshop on RF Hotspots". The available literature on thresholds for thermal damage and the validity of the thermal dose (TD) model were discussed. RESULTS/CONCLUSIONS: The following global TD threshold guidelines for safe use of MR are proposed: 1. All persons: maximum local temperature of any tissue limited to 39 °C 2. Persons with compromised thermoregulation AND (a) Uncontrolled conditions: maximum local temperature limited to 39 °C (b) Controlled conditions: TD < 2 CEM43°C 3. Persons with uncompromised thermoregulation AND (a) Uncontrolled conditions: TD < 2 CEM43°C (b) Controlled conditions: TD < 9 CEM43°C The following definitions are applied: Controlled conditions A medical doctor or a dedicated trained person can respond instantly to heat-induced physiological stress Compromised thermoregulation All persons with impaired systemic or reduced local thermoregulation KEY POINTS: • Standard MRI can cause local heating by radiofrequency absorption. • Monitoring thermal dose (in units of CEM43°C) can control risk during MRI. • 9 CEM43°C seems an acceptable thermal dose threshold for most patients. • For skin, muscle, fat and bone,16 CEM43°C is likely acceptable.

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Published In

Eur Radiol

DOI

EISSN

1432-1084

Publication Date

August 2013

Volume

23

Issue

8

Start / End Page

2215 / 2227

Location

Germany

Related Subject Headings

  • Tissue Distribution
  • Time Factors
  • Species Specificity
  • Radio Waves
  • Practice Guidelines as Topic
  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Imaging
  • Hyperthermia, Induced
  • Humans
  • Hot Temperature
 

Citation

APA
Chicago
ICMJE
MLA
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van Rhoon, G. C., Samaras, T., Yarmolenko, P. S., Dewhirst, M. W., Neufeld, E., & Kuster, N. (2013). CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels? Eur Radiol, 23(8), 2215–2227. https://doi.org/10.1007/s00330-013-2825-y
Rhoon, Gerard C. van, Theodoros Samaras, Pavel S. Yarmolenko, Mark W. Dewhirst, Esra Neufeld, and Niels Kuster. “CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels?Eur Radiol 23, no. 8 (August 2013): 2215–27. https://doi.org/10.1007/s00330-013-2825-y.
van Rhoon GC, Samaras T, Yarmolenko PS, Dewhirst MW, Neufeld E, Kuster N. CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels? Eur Radiol. 2013 Aug;23(8):2215–27.
van Rhoon, Gerard C., et al. “CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels?Eur Radiol, vol. 23, no. 8, Aug. 2013, pp. 2215–27. Pubmed, doi:10.1007/s00330-013-2825-y.
van Rhoon GC, Samaras T, Yarmolenko PS, Dewhirst MW, Neufeld E, Kuster N. CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels? Eur Radiol. 2013 Aug;23(8):2215–2227.
Journal cover image

Published In

Eur Radiol

DOI

EISSN

1432-1084

Publication Date

August 2013

Volume

23

Issue

8

Start / End Page

2215 / 2227

Location

Germany

Related Subject Headings

  • Tissue Distribution
  • Time Factors
  • Species Specificity
  • Radio Waves
  • Practice Guidelines as Topic
  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Imaging
  • Hyperthermia, Induced
  • Humans
  • Hot Temperature