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A network-heuristic approach to improve the impact of genomic data on drug discovery.

Publication ,  Journal Article
Trister, AD; Huang, ES
Published in: Clin Pharmacol Ther
April 2013

The explosive growth of molecular diagnostic tests introduces the possibility of increasing our understanding of disease mechanisms in the clinic and promises to improve target identification for new therapies. A new paradigm is emerging in drug discovery that is driven by these clinically derived data. Unfortunately, the translation of novel insights into useful therapies remains costly and difficult. New clinical trial design and open validation of markers may reduce these barriers to clinical utility.

Duke Scholars

Published In

Clin Pharmacol Ther

DOI

EISSN

1532-6535

Publication Date

April 2013

Volume

93

Issue

4

Start / End Page

295 / 297

Location

United States

Related Subject Headings

  • Pharmacology & Pharmacy
  • Models, Genetic
  • Humans
  • Genomics
  • Drug Discovery
  • Biomarkers, Pharmacological
  • 1115 Pharmacology and Pharmaceutical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Trister, A. D., & Huang, E. S. (2013). A network-heuristic approach to improve the impact of genomic data on drug discovery. Clin Pharmacol Ther, 93(4), 295–297. https://doi.org/10.1038/clpt.2012.246
Trister, A. D., and E. S. Huang. “A network-heuristic approach to improve the impact of genomic data on drug discovery.Clin Pharmacol Ther 93, no. 4 (April 2013): 295–97. https://doi.org/10.1038/clpt.2012.246.
Trister AD, Huang ES. A network-heuristic approach to improve the impact of genomic data on drug discovery. Clin Pharmacol Ther. 2013 Apr;93(4):295–7.
Trister, A. D., and E. S. Huang. “A network-heuristic approach to improve the impact of genomic data on drug discovery.Clin Pharmacol Ther, vol. 93, no. 4, Apr. 2013, pp. 295–97. Pubmed, doi:10.1038/clpt.2012.246.
Trister AD, Huang ES. A network-heuristic approach to improve the impact of genomic data on drug discovery. Clin Pharmacol Ther. 2013 Apr;93(4):295–297.
Journal cover image

Published In

Clin Pharmacol Ther

DOI

EISSN

1532-6535

Publication Date

April 2013

Volume

93

Issue

4

Start / End Page

295 / 297

Location

United States

Related Subject Headings

  • Pharmacology & Pharmacy
  • Models, Genetic
  • Humans
  • Genomics
  • Drug Discovery
  • Biomarkers, Pharmacological
  • 1115 Pharmacology and Pharmaceutical Sciences