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Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.

Publication ,  Journal Article
Janssens, ACJW; Ioannidis, JPA; Bedrosian, S; Boffetta, P; Dolan, SM; Dowling, N; Fortier, I; Freedman, AN; Grimshaw, JM; Gulcher, J; Gwinn, M ...
Published in: Eur J Hum Genet
May 2011

The rapid and continuing progress in gene discovery for complex diseases is fueling interest in the potential application of genetic risk models for clinical and public health practice. The number of studies assessing the predictive ability is steadily increasing, but they vary widely in completeness of reporting and apparent quality. Transparent reporting of the strengths and weaknesses of these studies is important to facilitate the accumulation of evidence on genetic risk prediction. A multidisciplinary workshop sponsored by the Human Genome Epidemiology Network developed a checklist of 25 items recommended for strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS), building on the principles established by previous reporting guidelines. These recommendations aim to enhance the transparency, quality and completeness of study reporting, and thereby to improve the synthesis and application of information from multiple studies that might differ in design, conduct or analysis.

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Published In

Eur J Hum Genet

DOI

EISSN

1476-5438

Publication Date

May 2011

Volume

19

Issue

5

Start / End Page

18 p preceding 494

Location

England

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Models, Genetic
  • Humans
  • Genomics
  • Genome-Wide Association Study
  • Genetics & Heredity
  • 3202 Clinical sciences
  • 3105 Genetics
  • 1103 Clinical Sciences
  • 0604 Genetics
 

Citation

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Janssens, A. C. J. W., Ioannidis, J. P. A., Bedrosian, S., Boffetta, P., Dolan, S. M., Dowling, N., … Khoury, M. J. (2011). Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Hum Genet, 19(5), 18ppreceding494. https://doi.org/10.1038/ejhg.2011.27
Janssens, A Cecile J. W., John P. A. Ioannidis, Sara Bedrosian, Paolo Boffetta, Siobhan M. Dolan, Nicole Dowling, Isabel Fortier, et al. “Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.Eur J Hum Genet 19, no. 5 (May 2011): 18ppreceding494. https://doi.org/10.1038/ejhg.2011.27.
Janssens ACJW, Ioannidis JPA, Bedrosian S, Boffetta P, Dolan SM, Dowling N, et al. Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Hum Genet. 2011 May;19(5):18ppreceding494.
Janssens, A. Cecile J. W., et al. “Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.Eur J Hum Genet, vol. 19, no. 5, May 2011, p. 18ppreceding494. Pubmed, doi:10.1038/ejhg.2011.27.
Janssens ACJW, Ioannidis JPA, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J, Gwinn M, Hlatky MA, Janes H, Kraft P, Melillo S, O’Donnell CJ, Pencina MJ, Ransohoff D, Schully SD, Seminara D, Winn DM, Wright CF, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Hum Genet. 2011 May;19(5):18ppreceding494.

Published In

Eur J Hum Genet

DOI

EISSN

1476-5438

Publication Date

May 2011

Volume

19

Issue

5

Start / End Page

18 p preceding 494

Location

England

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Models, Genetic
  • Humans
  • Genomics
  • Genome-Wide Association Study
  • Genetics & Heredity
  • 3202 Clinical sciences
  • 3105 Genetics
  • 1103 Clinical Sciences
  • 0604 Genetics