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Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study.

Publication ,  Journal Article
Fox, CS; Pencina, MJ; Wilson, PWF; Paynter, NP; Vasan, RS; D'Agostino, RB
Published in: Diabetes Care
August 2008

OBJECTIVE: We assessed the lifetime risk of cardiovascular disease (CVD) among individuals with and without obesity and diabetes. RESEARCH DESIGN AND METHODS: Participants were drawn from the original and offspring cohorts of the Framingham Heart Study. Lifetime (30-year) risk of CVD was assessed using a modified Kaplan-Meier approach adjusting for the competing risk of death, beginning from age 50 years. RESULTS: Over 30 years, the lifetime risk of CVD among women with diabetes was 54.8% among normal-weight women and 78.8% among obese women. Among normal-weight men with diabetes, the lifetime risk of CVD was 78.6%, whereas it was 86.9% among obese men. CONCLUSIONS: The lifetime risk of CVD among individuals with diabetes is high, and this relationship is further accentuated with increasing adiposity.

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Published In

Diabetes Care

DOI

EISSN

1935-5548

Publication Date

August 2008

Volume

31

Issue

8

Start / End Page

1582 / 1584

Location

United States

Related Subject Headings

  • Time Factors
  • Risk Assessment
  • Obesity
  • Middle Aged
  • Male
  • Humans
  • Female
  • Endocrinology & Metabolism
  • Diabetes Complications
  • Cardiovascular Diseases
 

Citation

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Chicago
ICMJE
MLA
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Fox, C. S., Pencina, M. J., Wilson, P. W. F., Paynter, N. P., Vasan, R. S., & D’Agostino, R. B. (2008). Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study. Diabetes Care, 31(8), 1582–1584. https://doi.org/10.2337/dc08-0025
Fox, Caroline S., Michael J. Pencina, Peter W. F. Wilson, Nina P. Paynter, Ramachandran S. Vasan, and Ralph B. D’Agostino. “Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study.Diabetes Care 31, no. 8 (August 2008): 1582–84. https://doi.org/10.2337/dc08-0025.
Fox CS, Pencina MJ, Wilson PWF, Paynter NP, Vasan RS, D’Agostino RB. Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study. Diabetes Care. 2008 Aug;31(8):1582–4.
Fox, Caroline S., et al. “Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study.Diabetes Care, vol. 31, no. 8, Aug. 2008, pp. 1582–84. Pubmed, doi:10.2337/dc08-0025.
Fox CS, Pencina MJ, Wilson PWF, Paynter NP, Vasan RS, D’Agostino RB. Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study. Diabetes Care. 2008 Aug;31(8):1582–1584.

Published In

Diabetes Care

DOI

EISSN

1935-5548

Publication Date

August 2008

Volume

31

Issue

8

Start / End Page

1582 / 1584

Location

United States

Related Subject Headings

  • Time Factors
  • Risk Assessment
  • Obesity
  • Middle Aged
  • Male
  • Humans
  • Female
  • Endocrinology & Metabolism
  • Diabetes Complications
  • Cardiovascular Diseases