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Testis formation in the fetal mouse: dynamic and complex de novo tubulogenesis.

Publication ,  Journal Article
Cool, J; DeFalco, T; Capel, B
Published in: Wiley Interdiscip Rev Dev Biol
2012

Soon after Sry initiates male sex determination, cells in XY gonads undergo an unusual process of de novo cord formation that results in the organization of Sertoli cells into epithelial tubules enclosing germ cells and partitioning mesenchymal cells and vasculature to the interstitial space of the testis. Recent experiments investigating this dynamic process in four dimensions have begun to shed new light on the collective interactions of multiple cell types during morphogenesis of testis cords.

Duke Scholars

Published In

Wiley Interdiscip Rev Dev Biol

DOI

EISSN

1759-7692

Publication Date

2012

Volume

1

Issue

6

Start / End Page

847 / 859

Location

United States

Related Subject Headings

  • Testis
  • Sertoli Cells
  • Mice
  • Male
  • Leydig Cells
  • Gonads
  • Germ Cells
  • Extracellular Matrix
  • Endothelial Cells
  • Embryo, Mammalian
 

Citation

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Chicago
ICMJE
MLA
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Cool, J., DeFalco, T., & Capel, B. (2012). Testis formation in the fetal mouse: dynamic and complex de novo tubulogenesis. Wiley Interdiscip Rev Dev Biol, 1(6), 847–859. https://doi.org/10.1002/wdev.62
Cool, Jonah, Tony DeFalco, and Blanche Capel. “Testis formation in the fetal mouse: dynamic and complex de novo tubulogenesis.Wiley Interdiscip Rev Dev Biol 1, no. 6 (2012): 847–59. https://doi.org/10.1002/wdev.62.
Cool J, DeFalco T, Capel B. Testis formation in the fetal mouse: dynamic and complex de novo tubulogenesis. Wiley Interdiscip Rev Dev Biol. 2012;1(6):847–59.
Cool, Jonah, et al. “Testis formation in the fetal mouse: dynamic and complex de novo tubulogenesis.Wiley Interdiscip Rev Dev Biol, vol. 1, no. 6, 2012, pp. 847–59. Pubmed, doi:10.1002/wdev.62.
Cool J, DeFalco T, Capel B. Testis formation in the fetal mouse: dynamic and complex de novo tubulogenesis. Wiley Interdiscip Rev Dev Biol. 2012;1(6):847–859.
Journal cover image

Published In

Wiley Interdiscip Rev Dev Biol

DOI

EISSN

1759-7692

Publication Date

2012

Volume

1

Issue

6

Start / End Page

847 / 859

Location

United States

Related Subject Headings

  • Testis
  • Sertoli Cells
  • Mice
  • Male
  • Leydig Cells
  • Gonads
  • Germ Cells
  • Extracellular Matrix
  • Endothelial Cells
  • Embryo, Mammalian