Management of recurrent melanoma of the extremity

Perfusion chemotherapy with Phenylalanine mustard was employed for treatment of patients with recurrent melanoma limited to the extremity, and has resulted in a 5 yr survival rate of 28% in 43 patients. The side effects of this form of treatment have been minimal, and major extremity amputation has been avoided. The survival rates are approximately those which have been previously reported with major extremity amputation.

Duke Scholars

Author Hilliard Foster Seigler Surgical Oncology