Overview
I am a surgeon with interest in immune management of transplant recipients. I am particularly interested in therapies that influence T cell costimulation pathways and adjuvant therapies that facilitate costimulation blockade to prevent the rejection of transplanted organs without undue suppression of protective immunity. I am also interested in understanding how injury, such as that occurring during trauma or in elective surgery, influences immune responses and subsequent healing following injury.
Current Appointments & Affiliations
David C. Sabiston, Jr. Distinguished Professor of Surgery
·
2015 - Present
Surgery, Abdominal Transplant Surgery,
Surgery
Professor of Surgery
·
2014 - Present
Surgery, Abdominal Transplant Surgery,
Surgery
Professor in Pediatrics
·
2014 - Present
Pediatrics,
Clinical Science Departments
Professor in Integrative Immunobiology
·
2014 - Present
Integrative Immunobiology,
Basic Science Departments
Member of the Duke Cancer Institute
·
2015 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Off-label use of alemtuzumab, belatacept, and rapamycin in kidney transplantation-Long-term real-world experience.
Journal Article Am J Transplant · January 2026 Conventional immunosuppressive regimens in kidney transplantation continue to pose significant challenges, largely due to their reliance on calcineurin inhibitors (CNIs) and corticosteroids. These challenges have driven the search for alternative regimens ... Full text Link to item CiteCo-Stimulatory Blockade and Infectious Risk in Solid Organ Transplantation
Journal Article American Journal of Transplantation · January 2026 Full text CiteCorrigendum to "Antibodies to angiotensin II type 1 receptor and endothelin type A receptor are associated with cytokine production enriched for type 2 immune response and antibody production in pediatric kidney transplant recipients" [American Journal of Transplantation. Volume 25, Issue 11, November 2025, Pages 2329-2344].
Journal Article Am J Transplant · December 12, 2025 Full text Link to item CiteRecent Grants
Stimulating Access to Research in Residency (StARR) - NIAID
Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of Allergy and Infectious Diseases · 2018 - 2029Advanced Immunobiology Traning Program for Surgeons
Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2019 - 2029Tolerance to Allogeneic Hearts via Implantation of Cultured Donor Thymus
ResearchAdvisor · Awarded by National Institutes of Health · 2025 - 2028View All Grants
Education, Training & Certifications
Duke University ·
1992
Ph.D.
Duke University, School of Medicine ·
1987
M.D.
Old Dominion University ·
1983
B.S.