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Allan Douglas Kirk

David C. Sabiston, Jr. Distinguished Professor of Surgery
Surgery, Abdominal Transplant Surgery

Selected Grants


Stimulating Access to Research in Residency (StARR) - NIAID

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2018 - 2029

Advanced Immunobiology Traning Program for Surgeons

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2029

Targeting the B Cell Response to Treat Antibody-Mediated Rejection

ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2028

Determining the Role of Spp1+ Macrophages in Muscle Regeneration in Peripheral Arterial Disease

ResearchCo-Mentor · Awarded by National Institutes of Health · 2024 - 2027

Genetic engineering of kidney allografts by ex vivo perfusion delivery of adeno-associated viral vectors

ResearchCo-Principal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

Stimulating Access to Research in Residency (StARR) - NIAID

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2018 - 2029

Advanced Immunobiology Traning Program for Surgeons

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2029

Targeting the B Cell Response to Treat Antibody-Mediated Rejection

ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2028

Determining the Role of Spp1+ Macrophages in Muscle Regeneration in Peripheral Arterial Disease

ResearchCo-Mentor · Awarded by National Institutes of Health · 2024 - 2027

Genetic engineering of kidney allografts by ex vivo perfusion delivery of adeno-associated viral vectors

ResearchCo-Principal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

Elucidating the mechanisms of mesenchymal progenitor cells in the pathophysiology of Peripheral Arterial Disease

ResearchMentor · Awarded by American Surgical Association Foundation · 2024 - 2026

SC21 WounDx Decision Support Tool

ResearchPrincipal Investigator · Awarded by Henry M. Jackson Foundation · 2023 - 2026

The impact of targeting CD40-CD154 pathway in nonhuman primate vascularized composite allograft model

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2025

Advancing Transplantation Outcomes in Children - Mechnistic and Clinical (milestone)

Clinical TrialCo Investigator · Awarded by Boston Children's Hospital · 2021 - 2025

Neonatal porcine islet xenografts for the treatment of type 1 diabetes

ResearchPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2014 - 2025

Basic Immunology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2020 - 2025

Surgical Critical Care Initiative (SC2I): Civilian application of military decision support tools for critically injured patients.

ResearchPrincipal Investigator · Awarded by Henry M. Jackson Foundation · 2021 - 2025

Genetic approaches to skin regeneration in zebrafish

ResearchCo-Mentor · Awarded by National Institutes of Health · 2020 - 2025

TEACH Clinical Trial

Clinical TrialPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2018 - 2025

(TEACH) Immune Tolerance Network

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2018 - 2025

Viela Bio Inc., VIB4920 Drug Study for Kidney Transplant Patients

Clinical TrialPrincipal Investigator · Awarded by Viela Bio, Inc. · 2019 - 2024

Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTG)

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2018 - 2024

Unified Program for Therapeutics in Children

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2019 - 2024

ITN Study: EP234: Real time flow cytometry at Duke for TEACH

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2018 - 2024

AX-158: Utilizing Nck Inhibition as Immunomodulation in Allotransplantation

ResearchPrincipal Investigator · Awarded by Artax Biopharma, Inc. · 2021 - 2023

ITN056ST Optimal Co-Chair Protocol

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2014 - 2023

Examining the Depletional Profile of the Anti-CD2

ResearchPrincipal Investigator · Awarded by American Society of Transplant Surgeons · 2020 - 2021

Determining Proliferative Potential and Factors Necessary for the Proliferation

ResearchPrincipal Investigator · Awarded by American Society of Transplant Surgeons · 2020 - 2021

Immunomodulation to Optimize Vascularized Composite Allograft Integration for Limb Loss Therapy

ResearchCo Investigator · Awarded by Department of Defense · 2015 - 2021

Sc2i

ResearchPrincipal Investigator · Awarded by Henry M. Jackson Foundation · 2020 - 2021

The Lung Transplant Clinical Trials Network (LT-CTN)

ResearchCo Investigator · Awarded by National Institutes of Health · 2014 - 2021

Nonhuman Primate Reagent Resources

ResearchPrincipal Investigator · Awarded by University of Massachusetts Medical School · 2019 - 2021

Mechanisms of Belatacept-resistant Renal Allograft Rejection

ResearchPrincipal Investigator · Awarded by Bristol-Myers Squibb Company · 2020 - 2021

Donor apoptotic cell infusion for tolerance to monkey kidney allografts

ResearchPrincipal Investigator · Awarded by The Board of Regents of the University of Wisconsin System · 2019 - 2021

Immune Tolerance Network - Flow Cytometry

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2014 - 2021

American Journal of Transplantation

ResearchPrincipal Investigator · Awarded by American Society of Transplantation · 2016 - 2020

Interface of Mitochondrial Quality Control and Immune Activation in Heart Transplant

ResearchMentor · Awarded by Foundation for Anesthesia Education and Research · 2018 - 2020

Positioning Vascilarized Composite Allotramsplantation within the Spectrum of Transplantation

ResearchCo Investigator · Awarded by Department of Defense · 2014 - 2020

Phase 2 Study of Belatacept, Alemtuzumab, and Sirolimus in Renal Transplantation

ResearchPrincipal Investigator · Awarded by Food and Drug Administration · 2015 - 2020

Establishing a Linear Program for the Development of Co-stimulation Resistant T-cells

FellowshipPrincipal Investigator · Awarded by American Society of Transplant Surgeons · 2019 - 2020

T cell Receptor Diversity as a Determinant of Co-stimulation Blockade Resistance

FellowshipPrincipal Investigator · Awarded by American Society of Transplant Surgeons · 2019 - 2020

SC2i

ResearchPrincipal Investigator · Awarded by Henry M. Jackson Foundation · 2014 - 2020

ITN iWITH Project

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2018 - 2020

Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients

ResearchPrincipal Investigator · Awarded by University of California - San Francisco · 2014 - 2019

CD57+CD4+ T cells in Belatacept-resistant Renal Allograft Rejection

ResearchPrincipal Investigator · Awarded by Bristol-Myers Squibb Company · 2016 - 2019

EP86: Flow Cytometry for Liver Transplant Tolerance Enhanced by Sirolimus Therapy

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2018 - 2019

The impact of Epstein Barr virus infection on the immune response in pediatric transplant recipients

ResearchPrincipal Investigator · Awarded by Stanford University · 2018 - 2019

(TEACH) Atemtuzumab, Costimulation Blockade and Sirolimus: A Tolerogenic Canvas for Donor Antigen Delivery via Mesenchymal

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2014 - 2018

Role of Mitochondrial Injury in the Pathogenesis of Primary Graft Dysfunction Following Cardiac Transplantation

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2018

Transplant Tolerance in Non-Human Primates

ResearchPrincipal Investigator · Awarded by Emory University · 2014 - 2017

T Cell Maturation and the Nexus of Viral- and Allo-Immunity

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2017

Mouse Heart Transplant

ResearchPrincipal Investigator · Awarded by Quadriga BioSciences, Inc. · 2017 - 2017

The Role of Rapamycin in Altering Graft Endothelial Cell Alloimmunogenicity

FellowshipPrincipal Investigator · Awarded by American Society of Transplant Surgeons · 2016 - 2017

Role of Mitochondrial Injury in the Pathogenesis of Primary Graft Dysfunction Following Cardiac Transplantation

ResearchPrincipal Investigator · Awarded by American Society of Transplantation · 2016 - 2017

Exercise, Nitric Oxide Bioavailability and Arteriovenous Fistula Maturation

Clinical TrialCollaborator · Awarded by National Institutes of Health · 2014 - 2017

Immune Tolerance Network - Flow Cytometry

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2016 - 2017

ASTS-Alexion Presidential Student Mentor Grant

FellowshipPrincipal Investigator · Awarded by American Society of Transplant Surgeons · 2015 - 2016

Development of a Composite Tissue Allotransplantation Research Program

ResearchCollaborator · Awarded by Emory University · 2014 - 2016

CD57+CD4+ T cells in Belatacept-resistant Renal Allograft Rejection

ResearchPrincipal Investigator · Awarded by Bristol-Myers Squibb Company · 2014 - 2015

Transplant Tolerance in Non-Human Primates

ResearchPrincipal Investigator · Awarded by Emory University · 2014 - 2014

External Relationships


  • AskBio
  • Bristol-Myers Squibb
  • CareDx
  • Clinetic (formerly MedBlue Data)
  • Eledon Pharmaceuticals
  • AskBio
  • Bristol-Myers Squibb
  • CareDx
  • Clinetic (formerly MedBlue Data)
  • Eledon Pharmaceuticals
  • Innoskel
  • MedBlue Incubator
  • Novartis pharmaceuticals
  • PeriOptions
  • Sana Biotechnology Inc.
  • Sanofi Genzyme
  • Surgical Safety Technologies
  • United Therapeutics Corp.
  • Veloxis
  • Vertex Pharmaceuticals Inc.
  • egenesis

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.