Mental Health and Substance Use Among Patients in a North Carolina HIV Clinic.

Journal Article (Journal Article)

BACKGROUND: The HIV/AIDS epidemic is a significant public health concern in North Carolina, and previous research has pointed to elevated mental health distress and substance use among HIV-infected populations, which may impact patients' adherence to medications. The aims of this study were to describe the prevalence of mental health and substance use issues among patients of a North Carolina HIV clinic, to examine differences by demographic characteristics, and to examine factors associated with suboptimal adherence to HIV medications. METHODS: This study was a secondary analysis of clinical data routinely collected through a health behavior questionnaire at a large HIV clinic in North Carolina. We analyzed data collected from February 2011 to August 2012. RESULTS: The sample included 1,398 patients. Overall, 12.2% of patients endorsed current symptomology indicative of moderate or severe levels of depression, and 38.6% reported receiving a psychiatric diagnosis at some point in their life. Additionally, 19.1% had indications of current problematic drinking, and 8.2% reported problematic drug use. Nearly one-quarter (22.1%) reported suboptimal adherence to HIV medications. Factors associated with poor adherence included racial/ethnic minority, age less than 35 years, and indications of moderate or severe depression. LIMITATIONS: The questionnaire was not completed systematically in the clinic, which may limit generalizability, and self-reported measures may have introduced social desirability bias. CONCLUSION: Patients were willing to disclose mental health distress, substance use, and suboptimal medication adherence to providers, which highlights the importance of routinely assessing these behaviors during clinic visits. Our findings suggest that treating depression may be an effective strategy to improve adherence to HIV medications.

Full Text

Duke Authors

Cited Authors

  • Skalski, LM; Watt, MH; MacFarlane, JC; Proeschold-Bell, RJ; Stout, JE; Sikkema, KJ

Published Date

  • 2015

Published In

Volume / Issue

  • 76 / 3

Start / End Page

  • 148 - 155

PubMed ID

  • 26510216

Pubmed Central ID

  • PMC4773024

International Standard Serial Number (ISSN)

  • 0029-2559

Digital Object Identifier (DOI)

  • 10.18043/ncm.76.3.148


  • eng

Conference Location

  • United States