Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography.

Journal Article (Journal Article)

Clinical management of burn injuries depends upon an accurate assessment of the depth of the wound. Current diagnostic methods rely primarily on subjective visual inspection, which can produce variable results. In this study, spectroscopic optical coherence tomography was used to objectively evaluate burn injuries in vivo in a mouse model. Significant spectral differences were observed and correlated with the depth of the injury as determined by histopathology. The relevance of these results to clinical burn management in human tissues is discussed.

Full Text

Duke Authors

Cited Authors

  • Zhao, Y; Maher, JR; Kim, J; Selim, MA; Levinson, H; Wax, A

Published Date

  • September 1, 2015

Published In

Volume / Issue

  • 6 / 9

Start / End Page

  • 3339 - 3345

PubMed ID

  • 26417505

Pubmed Central ID

  • PMC4574661

International Standard Serial Number (ISSN)

  • 2156-7085

Digital Object Identifier (DOI)

  • 10.1364/BOE.6.003339


  • eng

Conference Location

  • United States