Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography.
Journal Article (Journal Article)
Clinical management of burn injuries depends upon an accurate assessment of the depth of the wound. Current diagnostic methods rely primarily on subjective visual inspection, which can produce variable results. In this study, spectroscopic optical coherence tomography was used to objectively evaluate burn injuries in vivo in a mouse model. Significant spectral differences were observed and correlated with the depth of the injury as determined by histopathology. The relevance of these results to clinical burn management in human tissues is discussed.
- Zhao, Y; Maher, JR; Kim, J; Selim, MA; Levinson, H; Wax, A
- September 1, 2015
Volume / Issue
- 6 / 9
Start / End Page
- 3339 - 3345
Pubmed Central ID
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)
- United States