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Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography.

Publication ,  Journal Article
Zhao, Y; Maher, JR; Kim, J; Selim, MA; Levinson, H; Wax, A
Published in: Biomed Opt Express
September 1, 2015

Clinical management of burn injuries depends upon an accurate assessment of the depth of the wound. Current diagnostic methods rely primarily on subjective visual inspection, which can produce variable results. In this study, spectroscopic optical coherence tomography was used to objectively evaluate burn injuries in vivo in a mouse model. Significant spectral differences were observed and correlated with the depth of the injury as determined by histopathology. The relevance of these results to clinical burn management in human tissues is discussed.

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Published In

Biomed Opt Express

DOI

ISSN

2156-7085

Publication Date

September 1, 2015

Volume

6

Issue

9

Start / End Page

3339 / 3345

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics
 

Citation

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Zhao, Y., Maher, J. R., Kim, J., Selim, M. A., Levinson, H., & Wax, A. (2015). Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography. Biomed Opt Express, 6(9), 3339–3345. https://doi.org/10.1364/BOE.6.003339
Zhao, Yang, Jason R. Maher, Jina Kim, Maria Angelica Selim, Howard Levinson, and Adam Wax. “Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography.Biomed Opt Express 6, no. 9 (September 1, 2015): 3339–45. https://doi.org/10.1364/BOE.6.003339.
Zhao Y, Maher JR, Kim J, Selim MA, Levinson H, Wax A. Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography. Biomed Opt Express. 2015 Sep 1;6(9):3339–45.
Zhao, Yang, et al. “Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography.Biomed Opt Express, vol. 6, no. 9, Sept. 2015, pp. 3339–45. Pubmed, doi:10.1364/BOE.6.003339.
Zhao Y, Maher JR, Kim J, Selim MA, Levinson H, Wax A. Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography. Biomed Opt Express. 2015 Sep 1;6(9):3339–3345.
Journal cover image

Published In

Biomed Opt Express

DOI

ISSN

2156-7085

Publication Date

September 1, 2015

Volume

6

Issue

9

Start / End Page

3339 / 3345

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics