Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography.
Publication
, Journal Article
Zhao, Y; Maher, JR; Kim, J; Selim, MA; Levinson, H; Wax, A
Published in: Biomed Opt Express
September 1, 2015
Clinical management of burn injuries depends upon an accurate assessment of the depth of the wound. Current diagnostic methods rely primarily on subjective visual inspection, which can produce variable results. In this study, spectroscopic optical coherence tomography was used to objectively evaluate burn injuries in vivo in a mouse model. Significant spectral differences were observed and correlated with the depth of the injury as determined by histopathology. The relevance of these results to clinical burn management in human tissues is discussed.
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Published In
Biomed Opt Express
DOI
ISSN
2156-7085
Publication Date
September 1, 2015
Volume
6
Issue
9
Start / End Page
3339 / 3345
Location
United States
Related Subject Headings
- 5102 Atomic, molecular and optical physics
- 4003 Biomedical engineering
- 3212 Ophthalmology and optometry
- 0912 Materials Engineering
- 0205 Optical Physics
Citation
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NLM
Zhao, Y., Maher, J. R., Kim, J., Selim, M. A., Levinson, H., & Wax, A. (2015). Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography. Biomed Opt Express, 6(9), 3339–3345. https://doi.org/10.1364/BOE.6.003339
Zhao, Yang, Jason R. Maher, Jina Kim, Maria Angelica Selim, Howard Levinson, and Adam Wax. “Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography.” Biomed Opt Express 6, no. 9 (September 1, 2015): 3339–45. https://doi.org/10.1364/BOE.6.003339.
Zhao Y, Maher JR, Kim J, Selim MA, Levinson H, Wax A. Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography. Biomed Opt Express. 2015 Sep 1;6(9):3339–45.
Zhao, Yang, et al. “Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography.” Biomed Opt Express, vol. 6, no. 9, Sept. 2015, pp. 3339–45. Pubmed, doi:10.1364/BOE.6.003339.
Zhao Y, Maher JR, Kim J, Selim MA, Levinson H, Wax A. Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography. Biomed Opt Express. 2015 Sep 1;6(9):3339–3345.
Published In
Biomed Opt Express
DOI
ISSN
2156-7085
Publication Date
September 1, 2015
Volume
6
Issue
9
Start / End Page
3339 / 3345
Location
United States
Related Subject Headings
- 5102 Atomic, molecular and optical physics
- 4003 Biomedical engineering
- 3212 Ophthalmology and optometry
- 0912 Materials Engineering
- 0205 Optical Physics