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Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer.

Publication ,  Journal Article
Povsic, TJ; Lawrence, MG; Lincoff, AM; Mehran, R; Rusconi, CP; Zelenkofske, SL; Huang, Z; Sailstad, J; Armstrong, PW; Steg, PG; Bode, C ...
Published in: J Allergy Clin Immunol
December 2016

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Published In

J Allergy Clin Immunol

DOI

EISSN

1097-6825

Publication Date

December 2016

Volume

138

Issue

6

Start / End Page

1712 / 1715

Location

United States

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Polyethylene Glycols
  • Multicenter Studies as Topic
  • Hypersensitivity, Immediate
  • Humans
  • Clinical Trials, Phase III as Topic
  • Aptamers, Nucleotide
  • Antibodies
  • Allergy
  • 3204 Immunology
 

Citation

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Povsic, T. J., Lawrence, M. G., Lincoff, A. M., Mehran, R., Rusconi, C. P., Zelenkofske, S. L., … REGULATE-PCI Investigators, . (2016). Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer. J Allergy Clin Immunol, 138(6), 1712–1715. https://doi.org/10.1016/j.jaci.2016.04.058
Povsic, Thomas J., Monica G. Lawrence, A Michael Lincoff, Roxana Mehran, Christopher P. Rusconi, Steven L. Zelenkofske, Zhen Huang, et al. “Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer.J Allergy Clin Immunol 138, no. 6 (December 2016): 1712–15. https://doi.org/10.1016/j.jaci.2016.04.058.
Povsic TJ, Lawrence MG, Lincoff AM, Mehran R, Rusconi CP, Zelenkofske SL, et al. Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer. J Allergy Clin Immunol. 2016 Dec;138(6):1712–5.
Povsic, Thomas J., et al. “Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer.J Allergy Clin Immunol, vol. 138, no. 6, Dec. 2016, pp. 1712–15. Pubmed, doi:10.1016/j.jaci.2016.04.058.
Povsic TJ, Lawrence MG, Lincoff AM, Mehran R, Rusconi CP, Zelenkofske SL, Huang Z, Sailstad J, Armstrong PW, Steg PG, Bode C, Becker RC, Alexander JH, Adkinson NF, Levinson AI, REGULATE-PCI Investigators. Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer. J Allergy Clin Immunol. 2016 Dec;138(6):1712–1715.
Journal cover image

Published In

J Allergy Clin Immunol

DOI

EISSN

1097-6825

Publication Date

December 2016

Volume

138

Issue

6

Start / End Page

1712 / 1715

Location

United States

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Polyethylene Glycols
  • Multicenter Studies as Topic
  • Hypersensitivity, Immediate
  • Humans
  • Clinical Trials, Phase III as Topic
  • Aptamers, Nucleotide
  • Antibodies
  • Allergy
  • 3204 Immunology