Ambulatory blood pressure in the dash diet trial: Effects of race and albuminuria.

Journal Article (Journal Article;Multicenter Study)

We evaluated whether low-grade albuminuria or black race modulates ambulatory blood pressure (BP) or nocturnal BP response to the DASH diet. Among 202 adults enrolled in the DASH multicenter trial who were fed the DASH or control diet for 8 weeks, reductions in 24-hour daytime and nighttime SBP and DBP were significantly larger for DASH compared to control. Median changes in nocturnal BP dipping were not significant. Compared to urine albumin excretion of <7 mg/d, ≥7 mg/d was associated with larger significant median reductions in 24-hour SBP (-7.3 vs -3.1 mm Hg), all measures of DBP (24-hour: -5.9 vs -1.8 mm Hg; daytime: -9.9 vs -4.0 mm Hg; nighttime -9.0 vs -2.0 mm Hg), and with increased nocturnal SBP dipping (2.3% vs -0.5%). Black race was associated with larger median reduction in 24-hour SBP only (-5.5 vs -2.4 mm Hg). This analysis suggests greater effect of DASH on ambulatory BP in the presence of low-grade albuminuria.

Full Text

Duke Authors

Cited Authors

  • Tyson, CC; Barnhart, H; Sapp, S; Poon, V; Lin, P-H; Svetkey, LP

Published Date

  • February 2018

Published In

Volume / Issue

  • 20 / 2

Start / End Page

  • 308 - 314

PubMed ID

  • 29384243

Pubmed Central ID

  • PMC5820120

Electronic International Standard Serial Number (EISSN)

  • 1751-7176

Digital Object Identifier (DOI)

  • 10.1111/jch.13170


  • eng

Conference Location

  • United States