Donor derived HSV hepatitis in a kidney transplant recipient leading to liver fibrosis and portal hypertension.

Journal Article (Journal Article)

The unexpected transmission of donor-derived infection through organ transplantation is a rare event with current donor screening practices. In this case report we describe a probable donor-derived transmission of Herpes Simplex Virus (HSV)-2 via deceased donor kidney transplantation resulting in HSV hepatitis in the recipient. This manifested as acute liver failure which resolved with appropriate anti-viral therapy. Following recovery from the acute liver insult, the patient developed fibrotic liver morphology and portal hypertension, an unusual departure from the typical course.

Full Text

Duke Authors

Cited Authors

  • Shaw, BI; Nanavati, AJ; Taylor, V; Miller, RA; Kappus, M; Barbas, AS

Published Date

  • February 2019

Published In

Volume / Issue

  • 21 / 1

Start / End Page

  • e13029 -

PubMed ID

  • 30431215

Electronic International Standard Serial Number (EISSN)

  • 1399-3062

Digital Object Identifier (DOI)

  • 10.1111/tid.13029


  • eng

Conference Location

  • Denmark