Donor derived HSV hepatitis in a kidney transplant recipient leading to liver fibrosis and portal hypertension.
Publication
, Journal Article
Shaw, BI; Nanavati, AJ; Taylor, V; Miller, RA; Kappus, M; Barbas, AS
Published in: Transpl Infect Dis
February 2019
The unexpected transmission of donor-derived infection through organ transplantation is a rare event with current donor screening practices. In this case report we describe a probable donor-derived transmission of Herpes Simplex Virus (HSV)-2 via deceased donor kidney transplantation resulting in HSV hepatitis in the recipient. This manifested as acute liver failure which resolved with appropriate anti-viral therapy. Following recovery from the acute liver insult, the patient developed fibrotic liver morphology and portal hypertension, an unusual departure from the typical course.
Duke Scholars
Published In
Transpl Infect Dis
DOI
EISSN
1399-3062
Publication Date
February 2019
Volume
21
Issue
1
Start / End Page
e13029
Location
Denmark
Related Subject Headings
- Treatment Outcome
- Surgery
- Liver Failure, Acute
- Liver Cirrhosis
- Liver
- Kidney Transplantation
- Kidney
- Hypertension, Portal
- Humans
- Herpesvirus 2, Human
Citation
APA
Chicago
ICMJE
MLA
NLM
Shaw, B. I., Nanavati, A. J., Taylor, V., Miller, R. A., Kappus, M., & Barbas, A. S. (2019). Donor derived HSV hepatitis in a kidney transplant recipient leading to liver fibrosis and portal hypertension. Transpl Infect Dis, 21(1), e13029. https://doi.org/10.1111/tid.13029
Shaw, Brian I., Aditya J. Nanavati, Vanessa Taylor, Rachel A. Miller, Matthew Kappus, and Andrew S. Barbas. “Donor derived HSV hepatitis in a kidney transplant recipient leading to liver fibrosis and portal hypertension.” Transpl Infect Dis 21, no. 1 (February 2019): e13029. https://doi.org/10.1111/tid.13029.
Shaw BI, Nanavati AJ, Taylor V, Miller RA, Kappus M, Barbas AS. Donor derived HSV hepatitis in a kidney transplant recipient leading to liver fibrosis and portal hypertension. Transpl Infect Dis. 2019 Feb;21(1):e13029.
Shaw, Brian I., et al. “Donor derived HSV hepatitis in a kidney transplant recipient leading to liver fibrosis and portal hypertension.” Transpl Infect Dis, vol. 21, no. 1, Feb. 2019, p. e13029. Pubmed, doi:10.1111/tid.13029.
Shaw BI, Nanavati AJ, Taylor V, Miller RA, Kappus M, Barbas AS. Donor derived HSV hepatitis in a kidney transplant recipient leading to liver fibrosis and portal hypertension. Transpl Infect Dis. 2019 Feb;21(1):e13029.
Published In
Transpl Infect Dis
DOI
EISSN
1399-3062
Publication Date
February 2019
Volume
21
Issue
1
Start / End Page
e13029
Location
Denmark
Related Subject Headings
- Treatment Outcome
- Surgery
- Liver Failure, Acute
- Liver Cirrhosis
- Liver
- Kidney Transplantation
- Kidney
- Hypertension, Portal
- Humans
- Herpesvirus 2, Human