Morphological characteristics of early- versus late-onset macular edema in preterm infants.

Journal Article (Journal Article)

Macular images of infants with early-onset edema (occurring at or before 33 weeks' postmenstrual age [PMA]) and infants with late-onset edema (at or after 36 weeks' PMA) were compared. At first appearance, early-onset edema has a more severe morphology, with foveal bulging and elongated cystoid spaces than late-onset edema, which presents as small cystoid spaces outside the foveal center. Morphological variations may be an indicator of the underlying cause of edema in preterm infants. The presence of mostly parafoveal small cystoid spaces in the late-onset edema group may be suggestive of an association with neurological injury.

Full Text

Duke Authors

Cited Authors

  • Mangalesh, S; Wong, BM; Chen, X; Tran-Viet, D; Stinnett, SS; Sarin, N; Winter, KP; Vajzovic, L; Freedman, SF; Toth, CA

Published Date

  • October 2020

Published In

Volume / Issue

  • 24 / 5

Start / End Page

  • 303 - 306

PubMed ID

  • 32942022

Pubmed Central ID

  • PMC8006576

Electronic International Standard Serial Number (EISSN)

  • 1528-3933

Digital Object Identifier (DOI)

  • 10.1016/j.jaapos.2020.06.006


  • eng

Conference Location

  • United States