Overview
My current research interests include:
Childhood glaucomas - With a large referral practice of children with pediatric glaucomas of all types, Freedman is evaluating existing and new management strategies for treating refractory congenital and childhood glaucomas, including the use of pharmacologic agents, as well as modification of surgical interventions. Freedman has an on-going collaboration with Duke colleagues to study the genetics of pediatric glaucoma. In addition to an active clinical research program, she regularly lectures and directs workshop at national meetings aimed at educating other ophthalmologists about current strategies and controversies in managing children with refractory glaucoma.
Retinopathy of Prematurity - Freedman was the principal investigator at the Duke-UNC Center for the NIH-sponsored, multi-center trial to evaluate early treatment for retinopathy of prematurity (ETROP). Together with colleague David Wallace, she provides eye care and treatment to the many premature children who graduate from the Neonatal Intensive Care units at DUHS. Freedman and Wallace are involved in clinical research involving the computerized evaluation of retinal blood vessels in ROP. Freedman and Wallace collaborate with Cynthia Toth and her Duke research team in applying the new imaging technique of Spectral Domain Optical Coherence Tomography to image children with retinopathy of prematurity and other retinal disorders. Efforts are ongoing to investigate the role of the anti-vascular endothelial growth factor drug, bevasizumab in treating severe ROP.
Strabismus associated with macular translocation surgery - Together with Cynthia Toth, Freedman continues to surgically treat the cyclotorsion and strabismus resulting from macular translocation surgery (now reserved for special cases of macular degeneration that are resistent to injection therapy. She has developed and published on new extraocular muscle surgical techniques to deal with this problem.
Childhood glaucomas - With a large referral practice of children with pediatric glaucomas of all types, Freedman is evaluating existing and new management strategies for treating refractory congenital and childhood glaucomas, including the use of pharmacologic agents, as well as modification of surgical interventions. Freedman has an on-going collaboration with Duke colleagues to study the genetics of pediatric glaucoma. In addition to an active clinical research program, she regularly lectures and directs workshop at national meetings aimed at educating other ophthalmologists about current strategies and controversies in managing children with refractory glaucoma.
Retinopathy of Prematurity - Freedman was the principal investigator at the Duke-UNC Center for the NIH-sponsored, multi-center trial to evaluate early treatment for retinopathy of prematurity (ETROP). Together with colleague David Wallace, she provides eye care and treatment to the many premature children who graduate from the Neonatal Intensive Care units at DUHS. Freedman and Wallace are involved in clinical research involving the computerized evaluation of retinal blood vessels in ROP. Freedman and Wallace collaborate with Cynthia Toth and her Duke research team in applying the new imaging technique of Spectral Domain Optical Coherence Tomography to image children with retinopathy of prematurity and other retinal disorders. Efforts are ongoing to investigate the role of the anti-vascular endothelial growth factor drug, bevasizumab in treating severe ROP.
Strabismus associated with macular translocation surgery - Together with Cynthia Toth, Freedman continues to surgically treat the cyclotorsion and strabismus resulting from macular translocation surgery (now reserved for special cases of macular degeneration that are resistent to injection therapy. She has developed and published on new extraocular muscle surgical techniques to deal with this problem.
Current Duke Appointments & Affiliations
Professor of Ophthalmology
·
2007 - Present
Ophthalmology,
Clinical Science Departments
Chief, Pediatric Ophthalmology
·
2008 - Present
Ophthalmology,
Clinical Science Departments
Professor of Pediatrics
·
2007 - Present
Pediatrics,
Clinical Science Departments
Recent Scholarly Works
Imaging infants and children with investigational handheld optical coherence tomography with widefield lens: a pilot study.
Journal article Graefes Arch Clin Exp Ophthalmol · July 2026 Full text Link to item CitePreterm Infant Stress During Noncontact Handheld Optical Coherence Tomography and Contact Fundus Photography.
Journal article JAMA Ophthalmol · July 1, 2026 IMPORTANCE: Limiting the stress of retinopathy of prematurity (ROP) assessments may be beneficial for preterm infants. OBJECTIVE: To compare stress in preterm infants from noncontact optical coherence tomography (OCT) vs contact fundus photography during R ... Full text Link to item CiteVery Preterm Infant Retinal Microanatomy at 36 Weeks' Postmenstrual Age and 2-Year Neurodevelopment.
Journal article JAMA Ophthalmol · July 1, 2026 IMPORTANCE: If noninvasive optical coherence tomography (OCT) retinal imaging could predict 2-year neurodevelopment of very preterm (VPT; <32 weeks' gestational age) infants in neonatal intensive care, it might help to guide management. OBJECTIVE: To evalu ... Full text Link to item CiteRecent Grants
Pediatric and Adult Clinical Trial of Handheld OCT (PEACH OCT)
Clinical TrialPrincipal Investigator · Awarded by Theia Imaging, LLC · 2026 - 2031Duke Ophthalmology Mentored Physician Scientist Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2026 - 2031Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care
ResearchCo Investigator · Awarded by National Institutes of Health · 2026 - 2030View All Grants
Education
Harvard University ·
1985
M.D.
Duke University ·
1981
B.S.