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Thirty-day outcomes and predictors of mortality following acute myocardial infarction in northern Tanzania: A prospective observational cohort study.

Publication ,  Journal Article
Goli, S; Sakita, FM; Kweka, GL; Tarimo, TG; Temu, G; Thielman, NM; Bettger, JP; Bloomfield, GS; Limkakeng, AT; Hertz, JT
Published in: Int J Cardiol
November 1, 2021

OBJECTIVE: There is a rising burden of myocardial infarction (MI) within sub-Saharan Africa. Prospective studies of detailed MI outcomes in the region are lacking. METHODS: Adult patients with confirmed MI from a prospective surveillance study in northern Tanzania were enrolled in a longitudinal cohort study after baseline health history, medication use, and sociodemographic data were obtained. Thirty days following hospital presentation, symptom status, rehospitalizations, medication use, and mortality were assessed via telephone or in-person interviews using a standardized follow-up questionnaire. Multivariate logistic regression was performed to identify baseline predictors of thirty-day mortality. RESULTS: Thirty-day follow-up was achieved for 150 (98.7%) of 152 enrolled participants. Of these, 85 (56.7%) survived to thirty-day follow-up. Of the surviving participants, 71 (83.5%) reported persistent anginal symptoms, four (4.7%) reported taking aspirin regularly, seven (8.2%) were able to identify MI as the reason for their hospitalization, and 17 (20.0%) had unscheduled rehospitalizations. Self-reported history of diabetes at baseline (OR 0.32, 95% CI 0.10-0.89, p = 0.04), self-reported history of hypertension at baseline (OR 0.34, 95% CI 0.15-0.74, p = 0.01), and antiplatelet use at initial presentation (OR 0.19, 95% CI 0.04-0.65, p = 0.02) were all associated with lower odds of thirty-day mortality. CONCLUSIONS: In northern Tanzania, thirty-day outcomes following acute MI are poor, and mortality is associated with self-awareness of comorbidities and medication usage. Further investigation is needed to develop interventions to improve care and outcomes of MI in Tanzania.

Duke Scholars

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Published In

Int J Cardiol

DOI

EISSN

1874-1754

Publication Date

November 1, 2021

Volume

342

Start / End Page

23 / 28

Location

Netherlands

Related Subject Headings

  • Tanzania
  • Risk Factors
  • Prospective Studies
  • Myocardial Infarction
  • Longitudinal Studies
  • Humans
  • Cohort Studies
  • Cardiovascular System & Hematology
  • 3201 Cardiovascular medicine and haematology
  • 1117 Public Health and Health Services
 

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Goli, S., Sakita, F. M., Kweka, G. L., Tarimo, T. G., Temu, G., Thielman, N. M., … Hertz, J. T. (2021). Thirty-day outcomes and predictors of mortality following acute myocardial infarction in northern Tanzania: A prospective observational cohort study. Int J Cardiol, 342, 23–28. https://doi.org/10.1016/j.ijcard.2021.08.002
Goli, Sumana, Francis M. Sakita, Godfrey L. Kweka, Tumsifu G. Tarimo, Gloria Temu, Nathan M. Thielman, Janet P. Bettger, Gerald S. Bloomfield, Alexander T. Limkakeng, and Julian T. Hertz. “Thirty-day outcomes and predictors of mortality following acute myocardial infarction in northern Tanzania: A prospective observational cohort study.Int J Cardiol 342 (November 1, 2021): 23–28. https://doi.org/10.1016/j.ijcard.2021.08.002.
Goli S, Sakita FM, Kweka GL, Tarimo TG, Temu G, Thielman NM, et al. Thirty-day outcomes and predictors of mortality following acute myocardial infarction in northern Tanzania: A prospective observational cohort study. Int J Cardiol. 2021 Nov 1;342:23–8.
Goli, Sumana, et al. “Thirty-day outcomes and predictors of mortality following acute myocardial infarction in northern Tanzania: A prospective observational cohort study.Int J Cardiol, vol. 342, Nov. 2021, pp. 23–28. Pubmed, doi:10.1016/j.ijcard.2021.08.002.
Goli S, Sakita FM, Kweka GL, Tarimo TG, Temu G, Thielman NM, Bettger JP, Bloomfield GS, Limkakeng AT, Hertz JT. Thirty-day outcomes and predictors of mortality following acute myocardial infarction in northern Tanzania: A prospective observational cohort study. Int J Cardiol. 2021 Nov 1;342:23–28.
Journal cover image

Published In

Int J Cardiol

DOI

EISSN

1874-1754

Publication Date

November 1, 2021

Volume

342

Start / End Page

23 / 28

Location

Netherlands

Related Subject Headings

  • Tanzania
  • Risk Factors
  • Prospective Studies
  • Myocardial Infarction
  • Longitudinal Studies
  • Humans
  • Cohort Studies
  • Cardiovascular System & Hematology
  • 3201 Cardiovascular medicine and haematology
  • 1117 Public Health and Health Services