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Cognitive behavioural therapy and medication for treatment of adolescent depression: a network meta-analysis.

Publication ,  Journal Article
Dardas, LA; Xu, H; Franklin, MS; Scott, J; Vance, A; van de Water, B; Pan, W
Published in: Behavioural and cognitive psychotherapy
May 2023

Cognitive behavioural therapy (CBT) and medication are widely accepted and useful interventions for individuals with depression. However, a gap remains in our current understanding of how CBT directly benefits adolescents with depression.The purpose of this study was to examine the short- and long-term effectiveness of CBT only, CBT+Medication, or Medication alone in reducing the duration of major depressive episodes, lessening internalizing and externalizing symptoms and improving global functioning.Data were extracted from 14 unique studies with a total of 35 comparisons. Network meta-analysis was conducted and p-scores, a measure of the extent of certainty that one treatment is better than another, were used to rank treatments.There was no significant difference between any two treatments for depression, nor internalizing or externalizing symptoms. For global functioning, CBT had significantly greater effect at the longest follow-up than CBT+Medication. CBT+Medication had the highest p-score for depression, short- and long-term effects, and internalizing and externalizing symptoms long-term effects. No indication of publication bias was found.Neither modality, CBT nor medication, is superior for treating adolescent depression. However, CBT was superior in improving global functioning, which is essential for meeting developmental goals.

Duke Scholars

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Published In

Behavioural and cognitive psychotherapy

DOI

EISSN

1469-1833

ISSN

1352-4658

Publication Date

May 2023

Volume

51

Issue

3

Start / End Page

230 / 245

Related Subject Headings

  • Network Meta-Analysis
  • Humans
  • Depressive Disorder, Major
  • Depression
  • Cognitive Behavioral Therapy
  • Clinical Psychology
  • Adolescent
  • 5203 Clinical and health psychology
  • 5201 Applied and developmental psychology
  • 1702 Cognitive Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Dardas, L. A., Xu, H., Franklin, M. S., Scott, J., Vance, A., van de Water, B., & Pan, W. (2023). Cognitive behavioural therapy and medication for treatment of adolescent depression: a network meta-analysis. Behavioural and Cognitive Psychotherapy, 51(3), 230–245. https://doi.org/10.1017/s1352465822000662
Dardas, Latefa Ali, Hanzhang Xu, Michelle Scotton Franklin, Jewel Scott, Ashlee Vance, Brittney van de Water, and Wei Pan. “Cognitive behavioural therapy and medication for treatment of adolescent depression: a network meta-analysis.Behavioural and Cognitive Psychotherapy 51, no. 3 (May 2023): 230–45. https://doi.org/10.1017/s1352465822000662.
Dardas LA, Xu H, Franklin MS, Scott J, Vance A, van de Water B, et al. Cognitive behavioural therapy and medication for treatment of adolescent depression: a network meta-analysis. Behavioural and cognitive psychotherapy. 2023 May;51(3):230–45.
Dardas, Latefa Ali, et al. “Cognitive behavioural therapy and medication for treatment of adolescent depression: a network meta-analysis.Behavioural and Cognitive Psychotherapy, vol. 51, no. 3, May 2023, pp. 230–45. Epmc, doi:10.1017/s1352465822000662.
Dardas LA, Xu H, Franklin MS, Scott J, Vance A, van de Water B, Pan W. Cognitive behavioural therapy and medication for treatment of adolescent depression: a network meta-analysis. Behavioural and cognitive psychotherapy. 2023 May;51(3):230–245.
Journal cover image

Published In

Behavioural and cognitive psychotherapy

DOI

EISSN

1469-1833

ISSN

1352-4658

Publication Date

May 2023

Volume

51

Issue

3

Start / End Page

230 / 245

Related Subject Headings

  • Network Meta-Analysis
  • Humans
  • Depressive Disorder, Major
  • Depression
  • Cognitive Behavioral Therapy
  • Clinical Psychology
  • Adolescent
  • 5203 Clinical and health psychology
  • 5201 Applied and developmental psychology
  • 1702 Cognitive Sciences