Recent developments in phasing and structure refinement for macromolecular crystallography.
Journal Article (Journal Article;Review)
Central to crystallographic structure solution is obtaining accurate phases in order to build a molecular model, ultimately followed by refinement of that model to optimize its fit to the experimental diffraction data and prior chemical knowledge. Recent advances in phasing and model refinement and validation algorithms make it possible to arrive at better electron density maps and more accurate models.
- Adams, PD; Afonine, PV; Grosse-Kunstleve, RW; Read, RJ; Richardson, JS; Richardson, DC; Terwilliger, TC
- October 2009
Volume / Issue
- 19 / 5
Start / End Page
- 566 - 572
Pubmed Central ID
Electronic International Standard Serial Number (EISSN)
Digital Object Identifier (DOI)