Recent developments in phasing and structure refinement for macromolecular crystallography.
Publication
, Journal Article
Adams, PD; Afonine, PV; Grosse-Kunstleve, RW; Read, RJ; Richardson, JS; Richardson, DC; Terwilliger, TC
Published in: Curr Opin Struct Biol
October 2009
Central to crystallographic structure solution is obtaining accurate phases in order to build a molecular model, ultimately followed by refinement of that model to optimize its fit to the experimental diffraction data and prior chemical knowledge. Recent advances in phasing and model refinement and validation algorithms make it possible to arrive at better electron density maps and more accurate models.
Duke Scholars
Published In
Curr Opin Struct Biol
DOI
EISSN
1879-033X
Publication Date
October 2009
Volume
19
Issue
5
Start / End Page
566 / 572
Location
England
Related Subject Headings
- Models, Molecular
- Macromolecular Substances
- Imaging, Three-Dimensional
- Humans
- Crystallography, X-Ray
- Biophysics
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology
- 0304 Medicinal and Biomolecular Chemistry
Citation
APA
Chicago
ICMJE
MLA
NLM
Adams, P. D., Afonine, P. V., Grosse-Kunstleve, R. W., Read, R. J., Richardson, J. S., Richardson, D. C., & Terwilliger, T. C. (2009). Recent developments in phasing and structure refinement for macromolecular crystallography. Curr Opin Struct Biol, 19(5), 566–572. https://doi.org/10.1016/j.sbi.2009.07.014
Adams, Paul D., Pavel V. Afonine, Ralf W. Grosse-Kunstleve, Randy J. Read, Jane S. Richardson, David C. Richardson, and Thomas C. Terwilliger. “Recent developments in phasing and structure refinement for macromolecular crystallography.” Curr Opin Struct Biol 19, no. 5 (October 2009): 566–72. https://doi.org/10.1016/j.sbi.2009.07.014.
Adams PD, Afonine PV, Grosse-Kunstleve RW, Read RJ, Richardson JS, Richardson DC, et al. Recent developments in phasing and structure refinement for macromolecular crystallography. Curr Opin Struct Biol. 2009 Oct;19(5):566–72.
Adams, Paul D., et al. “Recent developments in phasing and structure refinement for macromolecular crystallography.” Curr Opin Struct Biol, vol. 19, no. 5, Oct. 2009, pp. 566–72. Pubmed, doi:10.1016/j.sbi.2009.07.014.
Adams PD, Afonine PV, Grosse-Kunstleve RW, Read RJ, Richardson JS, Richardson DC, Terwilliger TC. Recent developments in phasing and structure refinement for macromolecular crystallography. Curr Opin Struct Biol. 2009 Oct;19(5):566–572.
Published In
Curr Opin Struct Biol
DOI
EISSN
1879-033X
Publication Date
October 2009
Volume
19
Issue
5
Start / End Page
566 / 572
Location
England
Related Subject Headings
- Models, Molecular
- Macromolecular Substances
- Imaging, Three-Dimensional
- Humans
- Crystallography, X-Ray
- Biophysics
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology
- 0304 Medicinal and Biomolecular Chemistry