Antifungal agents and therapy for infants and children with invasive fungal infections: a pharmacological perspective.

Journal Article (Journal Article;Review)

Invasive fungal infections, although relatively rare, are life-threatening diseases in premature infants and immunocompromised children. While many advances have been made in antifungal therapeutics in the last two decades, knowledge of the pharmacokinetics and pharmacodynamics of antifungal agents for infants and children remains incomplete. This review summarizes the pharmacology and clinical utility of currently available antifungal agents and discusses the opportunities and challenges for future research.

Full Text

Duke Authors

Cited Authors

  • Lestner, JM; Smith, PB; Cohen-Wolkowiez, M; Benjamin, DK; Hope, WW

Published Date

  • June 2013

Published In

Volume / Issue

  • 75 / 6

Start / End Page

  • 1381 - 1395

PubMed ID

  • 23126319

Pubmed Central ID

  • PMC3690098

Electronic International Standard Serial Number (EISSN)

  • 1365-2125

Digital Object Identifier (DOI)

  • 10.1111/bcp.12025


  • eng

Conference Location

  • England