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B-mode and acoustic radiation force impulse (ARFI) imaging of prostate zonal anatomy: comparison with 3T T2-weighted MR imaging.

Publication ,  Journal Article
Palmeri, ML; Miller, ZA; Glass, TJ; Garcia-Reyes, K; Gupta, RT; Rosenzweig, SJ; Kauffman, C; Polascik, TJ; Buck, A; Kulbacki, E; Madden, J ...
Published in: Ultrason Imaging
January 2015

Prostate cancer (PCa) is the most common non-cutaneous malignancy among men in the United States and the second leading cause of cancer-related death. Multi-parametric magnetic resonance imaging (mpMRI) has gained recent popularity to characterize PCa. Acoustic Radiation Force Impulse (ARFI) imaging has the potential to aid PCa diagnosis and management by using tissue stiffness to evaluate prostate zonal anatomy and lesions. MR and B-mode/ARFI in vivo imaging datasets were compared with one another and with gross pathology measurements made immediately after radical prostatectomy. Images were manually segmented in 3D Slicer to delineate the central gland (CG) and prostate capsule, and 3D models were rendered to evaluate zonal anatomy dimensions and volumes. Both imaging modalities showed good correlation between estimated organ volume and gross pathologic weights. Ultrasound and MR total prostate volumes were well correlated (R(2) = 0.77), but B-mode images yielded prostate volumes that were larger (16.82% ± 22.45%) than MR images, due to overestimation of the lateral dimension (18.4% ± 13.9%), with less significant differences in the other dimensions (7.4% ± 17.6%, anterior-to-posterior, and -10.8% ± 13.9%, apex-to-base). ARFI and MR CG volumes were also well correlated (R(2) = 0.85). CG volume differences were attributed to ARFI underestimation of the apex-to-base axis (-28.8% ± 9.4%) and ARFI overestimation of the lateral dimension (21.5% ± 14.3%). B-mode/ARFI imaging yielded prostate volumes and dimensions that were well correlated with MR T2-weighted image (T2WI) estimates, with biases in the lateral dimension due to poor contrast caused by extraprostatic fat. B-mode combined with ARFI imaging is a promising low-cost, portable, real-time modality that can complement mpMRI for PCa diagnosis, treatment planning, and management.

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Published In

Ultrason Imaging

DOI

EISSN

1096-0910

Publication Date

January 2015

Volume

37

Issue

1

Start / End Page

22 / 41

Location

England

Related Subject Headings

  • Prostate
  • Organ Size
  • Male
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans
  • Elasticity Imaging Techniques
  • Acoustics
  • 4003 Biomedical engineering
  • 0903 Biomedical Engineering
 

Citation

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Chicago
ICMJE
MLA
NLM
Palmeri, M. L., Miller, Z. A., Glass, T. J., Garcia-Reyes, K., Gupta, R. T., Rosenzweig, S. J., … Nightingale, K. R. (2015). B-mode and acoustic radiation force impulse (ARFI) imaging of prostate zonal anatomy: comparison with 3T T2-weighted MR imaging. Ultrason Imaging, 37(1), 22–41. https://doi.org/10.1177/0161734614542177
Palmeri, Mark L., Zachary A. Miller, Tyler J. Glass, Kirema Garcia-Reyes, Rajan T. Gupta, Stephen J. Rosenzweig, Christopher Kauffman, et al. “B-mode and acoustic radiation force impulse (ARFI) imaging of prostate zonal anatomy: comparison with 3T T2-weighted MR imaging.Ultrason Imaging 37, no. 1 (January 2015): 22–41. https://doi.org/10.1177/0161734614542177.
Palmeri ML, Miller ZA, Glass TJ, Garcia-Reyes K, Gupta RT, Rosenzweig SJ, et al. B-mode and acoustic radiation force impulse (ARFI) imaging of prostate zonal anatomy: comparison with 3T T2-weighted MR imaging. Ultrason Imaging. 2015 Jan;37(1):22–41.
Palmeri, Mark L., et al. “B-mode and acoustic radiation force impulse (ARFI) imaging of prostate zonal anatomy: comparison with 3T T2-weighted MR imaging.Ultrason Imaging, vol. 37, no. 1, Jan. 2015, pp. 22–41. Pubmed, doi:10.1177/0161734614542177.
Palmeri ML, Miller ZA, Glass TJ, Garcia-Reyes K, Gupta RT, Rosenzweig SJ, Kauffman C, Polascik TJ, Buck A, Kulbacki E, Madden J, Lipman SL, Rouze NC, Nightingale KR. B-mode and acoustic radiation force impulse (ARFI) imaging of prostate zonal anatomy: comparison with 3T T2-weighted MR imaging. Ultrason Imaging. 2015 Jan;37(1):22–41.
Journal cover image

Published In

Ultrason Imaging

DOI

EISSN

1096-0910

Publication Date

January 2015

Volume

37

Issue

1

Start / End Page

22 / 41

Location

England

Related Subject Headings

  • Prostate
  • Organ Size
  • Male
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans
  • Elasticity Imaging Techniques
  • Acoustics
  • 4003 Biomedical engineering
  • 0903 Biomedical Engineering