Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope.
Publication
, Journal Article
McNabb, RP; Tian, J; Farsiu, S; Izatt, JA; Lad, EM; Kuo, AN
Published in: Biomed Opt Express
September 1, 2017
Age-related macular degeneration (AMD) is a major cause of vision loss in the elderly. To better study the pathobiology of AMD, postmortem eyes offer an excellent opportunity to correlate optical coherence tomography (OCT) imaging characteristics with histopathology. However, postmortem eyes from autopsy present challenges to standard OCT imaging including opaque anterior segment structures and standard of care autopsy processing resulting in oblique views to the macula. To overcome these challenges, we report a custom periscope attached by a standard mount to an OCT sample arm and demonstrate high quality macular OCT acquisitions in autopsy-processed eyes.
Duke Scholars
Published In
Biomed Opt Express
DOI
ISSN
2156-7085
Publication Date
September 1, 2017
Volume
8
Issue
9
Start / End Page
4152 / 4159
Location
United States
Related Subject Headings
- 5102 Atomic, molecular and optical physics
- 4003 Biomedical engineering
- 3212 Ophthalmology and optometry
- 0912 Materials Engineering
- 0205 Optical Physics
Citation
APA
Chicago
ICMJE
MLA
NLM
McNabb, R. P., Tian, J., Farsiu, S., Izatt, J. A., Lad, E. M., & Kuo, A. N. (2017). Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope. Biomed Opt Express, 8(9), 4152–4159. https://doi.org/10.1364/BOE.8.004152
McNabb, Ryan P., James Tian, Sina Farsiu, Joseph A. Izatt, Eleonora M. Lad, and Anthony N. Kuo. “Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope.” Biomed Opt Express 8, no. 9 (September 1, 2017): 4152–59. https://doi.org/10.1364/BOE.8.004152.
McNabb RP, Tian J, Farsiu S, Izatt JA, Lad EM, Kuo AN. Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope. Biomed Opt Express. 2017 Sep 1;8(9):4152–9.
McNabb, Ryan P., et al. “Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope.” Biomed Opt Express, vol. 8, no. 9, Sept. 2017, pp. 4152–59. Pubmed, doi:10.1364/BOE.8.004152.
McNabb RP, Tian J, Farsiu S, Izatt JA, Lad EM, Kuo AN. Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope. Biomed Opt Express. 2017 Sep 1;8(9):4152–4159.
Published In
Biomed Opt Express
DOI
ISSN
2156-7085
Publication Date
September 1, 2017
Volume
8
Issue
9
Start / End Page
4152 / 4159
Location
United States
Related Subject Headings
- 5102 Atomic, molecular and optical physics
- 4003 Biomedical engineering
- 3212 Ophthalmology and optometry
- 0912 Materials Engineering
- 0205 Optical Physics