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Associations Between Residential Proximity to Traffic and Vascular Disease in a Cardiac Catheterization Cohort.

Publication ,  Journal Article
Ward-Caviness, CK; Kraus, WE; Blach, C; Haynes, CS; Dowdy, E; Miranda, ML; Devlin, R; Diaz-Sanchez, D; Cascio, WE; Mukerjee, S; Stallings, C ...
Published in: Arterioscler Thromb Vasc Biol
January 2018

OBJECTIVE: Exposure to mobile source emissions is nearly ubiquitous in developed nations and is associated with multiple adverse health outcomes. There is an ongoing need to understand the specificity of traffic exposure associations with vascular outcomes, particularly in individuals with cardiovascular disease. APPROACH AND RESULTS: We performed a cross-sectional study using 2124 individuals residing in North Carolina, United States, who received a cardiac catheterization at the Duke University Medical Center. Traffic-related exposure was assessed via 2 metrics: (1) the distance between the primary residence and the nearest major roadway; and (2) location of the primary residence in regions defined based on local traffic patterns. We examined 4 cardiovascular disease outcomes: hypertension, peripheral arterial disease, the number of diseased coronary vessels, and recent myocardial infarction. Statistical models were adjusted for race, sex, smoking, type 2 diabetes mellitus, body mass index, hyperlipidemia, and home value. Results are expressed in terms of the odds ratio (OR). A 23% decrease in residential distance to major roadways was associated with higher prevalence of peripheral arterial disease (OR=1.29; 95% confidence interval, 1.08-1.55) and hypertension (OR=1.15; 95% confidence interval, 1.01-1.31). Associations with peripheral arterial disease were strongest in men (OR=1.42; 95% confidence interval, 1.17-1.74) while associations with hypertension were strongest in women (OR=1.21; 95% confidence interval, 0.99-1.49). Neither myocardial infarction nor the number of diseased coronary vessels were associated with traffic exposure. CONCLUSIONS: Traffic-related exposure is associated with peripheral arterial disease and hypertension while no associations are observed for 2 coronary-specific vascular outcomes.

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Published In

Arterioscler Thromb Vasc Biol

DOI

EISSN

1524-4636

Publication Date

January 2018

Volume

38

Issue

1

Start / End Page

275 / 282

Location

United States

Related Subject Headings

  • Traffic-Related Pollution
  • Risk Factors
  • Risk Assessment
  • Residence Characteristics
  • Prevalence
  • Peripheral Arterial Disease
  • North Carolina
  • Myocardial Infarction
  • Middle Aged
  • Male
 

Citation

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Chicago
ICMJE
MLA
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Ward-Caviness, C. K., Kraus, W. E., Blach, C., Haynes, C. S., Dowdy, E., Miranda, M. L., … Hauser, E. R. (2018). Associations Between Residential Proximity to Traffic and Vascular Disease in a Cardiac Catheterization Cohort. Arterioscler Thromb Vasc Biol, 38(1), 275–282. https://doi.org/10.1161/ATVBAHA.117.310003
Ward-Caviness, Cavin K., William E. Kraus, Colette Blach, Carol S. Haynes, Elaine Dowdy, Marie Lynn Miranda, Robert Devlin, et al. “Associations Between Residential Proximity to Traffic and Vascular Disease in a Cardiac Catheterization Cohort.Arterioscler Thromb Vasc Biol 38, no. 1 (January 2018): 275–82. https://doi.org/10.1161/ATVBAHA.117.310003.
Ward-Caviness CK, Kraus WE, Blach C, Haynes CS, Dowdy E, Miranda ML, et al. Associations Between Residential Proximity to Traffic and Vascular Disease in a Cardiac Catheterization Cohort. Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):275–82.
Ward-Caviness, Cavin K., et al. “Associations Between Residential Proximity to Traffic and Vascular Disease in a Cardiac Catheterization Cohort.Arterioscler Thromb Vasc Biol, vol. 38, no. 1, Jan. 2018, pp. 275–82. Pubmed, doi:10.1161/ATVBAHA.117.310003.
Ward-Caviness CK, Kraus WE, Blach C, Haynes CS, Dowdy E, Miranda ML, Devlin R, Diaz-Sanchez D, Cascio WE, Mukerjee S, Stallings C, Smith LA, Gregory SG, Shah SH, Neas LM, Hauser ER. Associations Between Residential Proximity to Traffic and Vascular Disease in a Cardiac Catheterization Cohort. Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):275–282.

Published In

Arterioscler Thromb Vasc Biol

DOI

EISSN

1524-4636

Publication Date

January 2018

Volume

38

Issue

1

Start / End Page

275 / 282

Location

United States

Related Subject Headings

  • Traffic-Related Pollution
  • Risk Factors
  • Risk Assessment
  • Residence Characteristics
  • Prevalence
  • Peripheral Arterial Disease
  • North Carolina
  • Myocardial Infarction
  • Middle Aged
  • Male