Scholars@Duke publication: Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes.

Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes.

Publication , Journal Article

Rebeiz, AG; Roe, MT; Alexander, JH; Mahaffey, KW; Granger, CB; Peterson, ED; Califf, RM; Harrington, RA

Published in: Am J Med

January 15, 2004

Non-ST-segment elevation acute coronary syndromes are a dramatic manifestation of coronary artery disease. Multiple clinical trials have shown that early cardiac catheterization improves clinical outcomes in patients with non-ST-segment elevation acute coronary syndromes. Many antithrombotic agents effectively manage unstable coronary syndromes and serve as adjuncts to percutaneous coronary intervention. Yet, the growing number of pharmacologic agents makes early management of non-ST-segment elevation acute coronary syndromes increasingly complex. We review the current evidence regarding the optimal integration of early antithrombotic and antiplatelet therapies with early coronary angiography and subsequent revascularization.

Duke Scholars

Author Matthew Todd Roe Medicine, Cardiology

Author John Hunter Peel Alexander Medicine, Cardiology

Author Christopher Bull Granger Medicine, Cardiology

Published In

Am J Med

DOI

10.1016/j.amjmed.2003.09.028

ISSN

0002-9343

Publication Date

January 15, 2004

Volume

116

Issue

Start / End Page

119 / 129

Location

United States

Related Subject Headings

Ticlopidine
Thrombolytic Therapy
Risk Assessment
Platelet Glycoprotein GPIIb-IIIa Complex
Platelet Aggregation Inhibitors
Peptides
Myocardial Ischemia
Integrin beta3
Humans
Heparin, Low-Molecular-Weight

Citation

APA

Chicago

ICMJE

MLA

NLM

Rebeiz, A. G., Roe, M. T., Alexander, J. H., Mahaffey, K. W., Granger, C. B., Peterson, E. D., … Harrington, R. A. (2004). Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes. Am J Med, 116(2), 119–129. https://doi.org/10.1016/j.amjmed.2003.09.028

Rebeiz, Abdallah G., Matthew T. Roe, John H. Alexander, Kenneth W. Mahaffey, Christopher B. Granger, Eric D. Peterson, Robert M. Califf, and Robert A. Harrington. “Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes.” Am J Med 116, no. 2 (January 15, 2004): 119–29. https://doi.org/10.1016/j.amjmed.2003.09.028.

Rebeiz AG, Roe MT, Alexander JH, Mahaffey KW, Granger CB, Peterson ED, et al. Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes. Am J Med. 2004 Jan 15;116(2):119–29.

Rebeiz, Abdallah G., et al. “Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes.” Am J Med, vol. 116, no. 2, Jan. 2004, pp. 119–29. Pubmed, doi:10.1016/j.amjmed.2003.09.028.

Rebeiz AG, Roe MT, Alexander JH, Mahaffey KW, Granger CB, Peterson ED, Califf RM, Harrington RA. Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes. Am J Med. 2004 Jan 15;116(2):119–129.