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6D image guidance for spinal non-invasive stereotactic body radiation therapy: Comparison between ExacTrac X-ray 6D with kilo-voltage cone-beam CT.

Publication ,  Journal Article
Chang, Z; Wang, Z; Ma, J; O'Daniel, JC; Kirkpatrick, J; Yin, F-F
Published in: Radiother Oncol
April 2010

PURPOSE: To investigate setup discrepancies measured with ExacTrac X-ray 6 degree-of-freedom (6D) and cone-beam computed tomography (CBCT) for patients under treatments of stereotactic body radiation therapy (SBRT). MATERIALS AND METHODS: In this work, phantom and patient studies were performed. In the phantom studies, an anthropomorphic phantom was placed with pre-defined positions, and imaged with ExacTrac X-ray 6D and CBCT to test the accuracy of the imaging systems. In the patient studies, 16 spinal SBRT patient cases were retrospectively analyzed. The patients were initially positioned in customized immobilization cradles and then aligned with ExacTrac X-ray 6D and CBCT. The setup discrepancies were computed and quantitatively analyzed. RESULTS: This study indicates modest discrepancies between ExacTrac X-ray 6D and CBCT with spinal SBRT. The phantom experiments showed that translational and rotational discrepancies in root-mean-square (RMS) between ExacTrac X-ray 6D and CBCT were, respectively, <1.0mm and <1 degrees . In the retrospective patient studies, translational and rotational discrepancies in RMS between ExacTrac X-ray 6D and CBCT were <2.0mm and <1.5 degrees . CONCLUSIONS: ExacTrac X-ray 6D represents a potential alternative to CBCT; however, pre-caution should be taken when only ExacTrac X-ray 6D is used to guide SBRT with small setup margins.

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Published In

Radiother Oncol

DOI

EISSN

1879-0887

Publication Date

April 2010

Volume

95

Issue

1

Start / End Page

116 / 121

Location

Ireland

Related Subject Headings

  • Spinal Neoplasms
  • Retrospective Studies
  • Radiosurgery
  • Phantoms, Imaging
  • Oncology & Carcinogenesis
  • Humans
  • Cone-Beam Computed Tomography
  • 5105 Medical and biological physics
  • 3211 Oncology and carcinogenesis
  • 3202 Clinical sciences
 

Citation

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MLA
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Chang, Z., Wang, Z., Ma, J., O’Daniel, J. C., Kirkpatrick, J., & Yin, F.-F. (2010). 6D image guidance for spinal non-invasive stereotactic body radiation therapy: Comparison between ExacTrac X-ray 6D with kilo-voltage cone-beam CT. Radiother Oncol, 95(1), 116–121. https://doi.org/10.1016/j.radonc.2009.12.036
Chang, Zheng, Zhiheng Wang, Jinli Ma, Jennifer C. O’Daniel, John Kirkpatrick, and Fang-Fang Yin. “6D image guidance for spinal non-invasive stereotactic body radiation therapy: Comparison between ExacTrac X-ray 6D with kilo-voltage cone-beam CT.Radiother Oncol 95, no. 1 (April 2010): 116–21. https://doi.org/10.1016/j.radonc.2009.12.036.
Chang Z, Wang Z, Ma J, O’Daniel JC, Kirkpatrick J, Yin F-F. 6D image guidance for spinal non-invasive stereotactic body radiation therapy: Comparison between ExacTrac X-ray 6D with kilo-voltage cone-beam CT. Radiother Oncol. 2010 Apr;95(1):116–21.
Chang, Zheng, et al. “6D image guidance for spinal non-invasive stereotactic body radiation therapy: Comparison between ExacTrac X-ray 6D with kilo-voltage cone-beam CT.Radiother Oncol, vol. 95, no. 1, Apr. 2010, pp. 116–21. Pubmed, doi:10.1016/j.radonc.2009.12.036.
Chang Z, Wang Z, Ma J, O’Daniel JC, Kirkpatrick J, Yin F-F. 6D image guidance for spinal non-invasive stereotactic body radiation therapy: Comparison between ExacTrac X-ray 6D with kilo-voltage cone-beam CT. Radiother Oncol. 2010 Apr;95(1):116–121.
Journal cover image

Published In

Radiother Oncol

DOI

EISSN

1879-0887

Publication Date

April 2010

Volume

95

Issue

1

Start / End Page

116 / 121

Location

Ireland

Related Subject Headings

  • Spinal Neoplasms
  • Retrospective Studies
  • Radiosurgery
  • Phantoms, Imaging
  • Oncology & Carcinogenesis
  • Humans
  • Cone-Beam Computed Tomography
  • 5105 Medical and biological physics
  • 3211 Oncology and carcinogenesis
  • 3202 Clinical sciences