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Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study

Publication ,  Journal Article
Herickhoff, CD; Light, ED; Wolf, PD; Smith, SW; Grant, GA; Britz, GW
Published in: Proceedings - IEEE Ultrasonics Symposium
January 1, 2009

In this study, we investigated the feasibility of dual-mode intracranial catheter transducers for visualization and treatment of tumors in the brain. Feasibility is demonstrated in two ways: 1) by developing a 12 Fr, integrated matrix and linear array catheter transducer prototype for combined real-time 3D imaging and heating, and 2) by testing 3.5 Fr IVUS-catheter-packageable transducers for therapeutic potential. The 3.6 MHz, 12 Fr catheter acquired real-time 3D images of canine brain structures in vivo while placed in the superior sagittal sinus via a burr hole in the skull, and achieved a 3.5°C temperature rise in tissue-mimicking material at a 2 cm focus in vitro. The IVUS-sized prototype transducers were tested for maximum intensity and mechanical index, and a thermal model was used to extrapolate and estimate each transducer's maximum potential temperature rise in brain tissue. ©2009 IEEE.

Duke Scholars

Published In

Proceedings - IEEE Ultrasonics Symposium

DOI

ISSN

1051-0117

Publication Date

January 1, 2009

Start / End Page

1012 / 1015
 

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Herickhoff, C. D., Light, E. D., Wolf, P. D., Smith, S. W., Grant, G. A., & Britz, G. W. (2009). Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study. Proceedings - IEEE Ultrasonics Symposium, 1012–1015. https://doi.org/10.1109/ULTSYM.2009.5441798
Herickhoff, C. D., E. D. Light, P. D. Wolf, S. W. Smith, G. A. Grant, and G. W. Britz. “Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study.” Proceedings - IEEE Ultrasonics Symposium, January 1, 2009, 1012–15. https://doi.org/10.1109/ULTSYM.2009.5441798.
Herickhoff CD, Light ED, Wolf PD, Smith SW, Grant GA, Britz GW. Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study. Proceedings - IEEE Ultrasonics Symposium. 2009 Jan 1;1012–5.
Herickhoff, C. D., et al. “Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study.” Proceedings - IEEE Ultrasonics Symposium, Jan. 2009, pp. 1012–15. Scopus, doi:10.1109/ULTSYM.2009.5441798.
Herickhoff CD, Light ED, Wolf PD, Smith SW, Grant GA, Britz GW. Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study. Proceedings - IEEE Ultrasonics Symposium. 2009 Jan 1;1012–1015.

Published In

Proceedings - IEEE Ultrasonics Symposium

DOI

ISSN

1051-0117

Publication Date

January 1, 2009

Start / End Page

1012 / 1015