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Clinical Utility of Magnetic Resonance Thermal Imaging (MRTI) For Realtime Guidance of Deep Hyperthermia.

Publication ,  Journal Article
Stauffer, P; Craciunescu, O; Maccarini, P; Wyatt, C; Arunachalam, K; Arabe, O; Stakhursky, V; Li, Z; Soher, B; Macfall, J; Rangarao, S; Das, S ...
Published in: Proc SPIE Int Soc Opt Eng
February 25, 2009

A critical need has emerged for volumetric thermometry to visualize 3D temperature distributions in real time during deep hyperthermia treatments used as an adjuvant to radiation or chemotherapy for cancer. For the current effort, magnetic resonance thermal imaging (MRTI) is used to measure 2D temperature rise distributions in four cross sections of large extremity soft tissue sarcomas during hyperthermia treatments. Novel hardware and software techniques are described which improve the signal to noise ratio of MR images, minimize motion artifact from circulating coupling fluids, and provide accurate high resolution volumetric thermal dosimetry. For the first 10 extremity sarcoma patients, the mean difference between MRTI region of interest and adjacent interstitial point measurements during the period of steady state temperature was 0.85°C. With 1min temporal resolution of measurements in four image planes, this non-invasive MRTI approach has demonstrated its utility for accurate monitoring and realtime steering of heat into tumors at depth in the body.

Duke Scholars

Published In

Proc SPIE Int Soc Opt Eng

DOI

ISSN

0277-786X

Publication Date

February 25, 2009

Volume

7181

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering
 

Citation

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MLA
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Stauffer, P., Craciunescu, O., Maccarini, P., Wyatt, C., Arunachalam, K., Arabe, O., … Vujaskovic, Z. (2009). Clinical Utility of Magnetic Resonance Thermal Imaging (MRTI) For Realtime Guidance of Deep Hyperthermia. Proc SPIE Int Soc Opt Eng, 7181. https://doi.org/10.1117/12.812188
Stauffer, Pr, Oi Craciunescu, P. Maccarini, C. Wyatt, K. Arunachalam, O. Arabe, V. Stakhursky, et al. “Clinical Utility of Magnetic Resonance Thermal Imaging (MRTI) For Realtime Guidance of Deep Hyperthermia.Proc SPIE Int Soc Opt Eng 7181 (February 25, 2009). https://doi.org/10.1117/12.812188.
Stauffer P, Craciunescu O, Maccarini P, Wyatt C, Arunachalam K, Arabe O, et al. Clinical Utility of Magnetic Resonance Thermal Imaging (MRTI) For Realtime Guidance of Deep Hyperthermia. Proc SPIE Int Soc Opt Eng. 2009 Feb 25;7181.
Stauffer, Pr, et al. “Clinical Utility of Magnetic Resonance Thermal Imaging (MRTI) For Realtime Guidance of Deep Hyperthermia.Proc SPIE Int Soc Opt Eng, vol. 7181, Feb. 2009. Pubmed, doi:10.1117/12.812188.
Stauffer P, Craciunescu O, Maccarini P, Wyatt C, Arunachalam K, Arabe O, Stakhursky V, Li Z, Soher B, Macfall J, Rangarao S, Cheng K, Das S, Martins C, Charles C, Dewhirst M, Wong T, Jones E, Vujaskovic Z. Clinical Utility of Magnetic Resonance Thermal Imaging (MRTI) For Realtime Guidance of Deep Hyperthermia. Proc SPIE Int Soc Opt Eng. 2009 Feb 25;7181.

Published In

Proc SPIE Int Soc Opt Eng

DOI

ISSN

0277-786X

Publication Date

February 25, 2009

Volume

7181

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering