As an assistant professor of neurosurgery working in adult hydrocephalus, my research focuses on cerebrospinal fluid (CSF) pathways in the brain and the mechanisms by which hydrocephalus develops. In addition to intersecting every area of neurosurgery from pediatrics to trauma, abnormalities in CSF physiology have been implicated in a multitude of neurological diseases, from Alzheimer’s disease to depression.
My basic science research involves identifying the mechanisms of intracranial pressure regulation by choroid plexus epithelial cells. The lab uses genetic mouse models to explore important genes and/or proteins involved in CSF regulation. Our goal is to develop novel, long lasting and minimally invasive strategies to diagnose and treat CSF flow disorders.