Scholars@Duke
Cassandra K Kisby

Cassandra K Kisby

Assistant Professor of Obstetrics and Gynecology
Obstetrics and Gynecology, Urogynecology
cassandra.kisby@duke.edu
Box 3084, Durham, NC 27710
5324 McFarland Dr, Suite 310, Durham, NC 27707
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Selected Publications

Noncongenital Vaginal Obliteration: Surgical Restoration of Vaginal Patency for GVHD.

Journal Article J Minim Invasive Gynecol · March 15, 2024 STUDY OBJECTIVE: To provide a brief overview of noncongenital causes of vaginal obliteration and stenosis, discuss a unique case of vaginal agglutination in a patient who developed genital graft-versus-host disease (GVHD) after receiving a bone marrow tran ... Full text Link to item Cite

Impact of Severe Obesity on Major Perioperative Complications for Prolapse Surgery.

Journal Article Urogynecology (Phila) · January 16, 2024 IMPORTANCE: Obesity adds complexity to the decision of surgical approach for pelvic organ prolapse; data regarding perioperative complications are needed. OBJECTIVE: The aim of the study was to evaluate associations of body mass index (BMI) and surgical ap ... Full text Link to item Cite

Management of partial Müllerian agenesis: staged McIndoe procedure for the creation of a neovagina and utero-neovaginal unification.

Journal Article Int Urogynecol J · August 2023 INTRODUCTION: The objectives of this video are to provide a brief overview of Müllerian agenesis, discuss a case of partial vaginal agenesis with a functional uterus, and present the steps of a staged McIndoe procedure for the creation of a neovagina and u ... Full text Link to item Cite

A New Dimension in Pessary Care.

Journal Article Urogynecology (Phila) · June 1, 2023 Full text Link to item Cite

Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence.

Journal Article NPJ Regen Med · September 29, 2022 Urinary incontinence afflicts up to 40% of adult women in the United States. Stress urinary incontinence (SUI) accounts for approximately one-third of these cases, precipitating ~200,000 surgical procedures annually. Continence is maintained through the in ... Full text Link to item Cite

Three-Dimensional-Printed Vaginal Molds for Use After McIndoe Neovagina Creation.

Journal Article Obstet Gynecol · August 1, 2022 BACKGROUND: Surgical vaginoplasty is a highly successful treatment for congenital absence of the vagina. One key to long-term success is the use of an appropriate vaginal mold in the immediate postoperative period. We present the use of a three-dimensional ... Full text Link to item Cite

Vesicouterine Fistula: A Robotic Approach.

Journal Article Int Urogynecol J · June 2022 INTRODUCTION AND HYPOTHESIS: This video demonstrates surgical repair of a vesicouterine fistula via a robotic, uterine-sparing approach. METHODS: In this video, we present a vesicouterine fistula, which occurred after cesarean delivery. The patient present ... Full text Link to item Cite

Postoperative Urinary Incontinence in Diabetic Patients Undergoing Pelvic Reconstructive Surgery.

Journal Article Female Pelvic Med Reconstr Surg · June 1, 2022 IMPORTANCE: Diabetes is an independent risk factor for urinary incontinence, and its impact on rates of postoperative incontinence after pelvic reconstructive surgery remains unexplored. OBJECTIVE: The aim of the study was to compare the incidence of posto ... Full text Link to item Cite

Management of advanced prolapse including a bowel obstruction: expanding the role of transvaginal surgery.

Journal Article Int Urogynecol J · January 2022 INTRODUCTION AND HYPOTHESIS: We reviewed a case of concomitant advanced pelvic organ prolapse and partial small bowel obstruction managed via transvaginal small bowel resection and native tissue prolapse repair. METHODS: The patient is an 82-year-old woman ... Full text Link to item Cite

Surgical Outcomes in Urogynecology-Assessment of Perioperative and Postoperative Complications Relative to Preoperative Hemoglobin A1c-A Fellows Pelvic Research Network Study.

Journal Article Female Pelvic Med Reconstr Surg · January 1, 2022 OBJECTIVES: Poor control of diabetes mellitus is a known predictor of perioperative and postoperative complications. No literature to date has established a hemoglobin A1c (HbA1c) cutoff for risk stratification in the urogynecology population. We sought to ... Full text Link to item Cite

Exosome-Induced Vaginal Tissue Regeneration in a Porcine Mesh Exposure Model.

Journal Article Female Pelvic Med Reconstr Surg · October 1, 2021 OBJECTIVES: The purpose of this study was to explore the utility of an injectable purified exosome product derived from human apheresis blood to (1) augment surgical closure of vaginal mesh exposures, and (2) serve as a stand-alone therapy for vaginal mesh ... Full text Link to item Cite

Teaching the art of LeFort colpocleisis: a moderate-fidelity, low-cost simulation model.

Journal Article Int Urogynecol J · August 2021 The objective was to demonstrate the build and use of a low-cost, moderate-fidelity simulation model for LeFort colpocleisis. We a present a video demonstrating the creation of a LeFort colpocleisis model, the mounting of this model to a pre-existing vagin ... Full text Link to item Cite

Impact of Repeat Dosing and Mesh Exposure Chronicity on Exosome-Induced Vaginal Tissue Regeneration in a Porcine Mesh Exposure Model.

Journal Article Female Pelvic Med Reconstr Surg · March 1, 2021 OBJECTIVE: The aim of the study was to compare vaginal wound healing after exosome injection in a porcine mesh exposure model with (1) single versus multiple dose regimens and (2) acute versus subacute exposure. METHODS: Six 80-kg Yorkshire-crossed swine e ... Full text Link to item Cite

Perioperative Complications in Minimally Invasive Sacrocolpopexy Versus Transvaginal Mesh in the Management of Pelvic Organ Prolapse: Analysis of a National Multi-institutional Dataset.

Journal Article Female Pelvic Med Reconstr Surg · February 1, 2021 OBJECTIVES: The objective of this study was to evaluate perioperative complications in women who underwent minimally invasive sacrocolpopexy (MISC) versus mesh-augmented vaginal repair (vaginal mesh) for pelvic organ prolapse. METHODS: We identified patien ... Full text Link to item Cite

Surgical management of stress urinary incontinence following traumatic pelvic injury.

Journal Article Int Urogynecol J · January 2021 INTRODUCTION AND HYPOTHESIS: The objective was to discuss the evaluation and management of stress urinary incontinence (SUI) following traumatic pelvic injury by use of a video case. METHODS: We present a patient with severe SUI following pelvic trauma and ... Full text Link to item Cite

Surgical management of mid- and upper-vaginal constriction rings

Conference AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY · 2021 Cite

Noncongenital Vaginal Obliteration: Surgical Restoration of Vaginal Patency for GVHD.

Journal Article J Minim Invasive Gynecol · March 15, 2024 STUDY OBJECTIVE: To provide a brief overview of noncongenital causes of vaginal obliteration and stenosis, discuss a unique case of vaginal agglutination in a patient who developed genital graft-versus-host disease (GVHD) after receiving a bone marrow tran ... Full text Link to item Cite

Impact of Severe Obesity on Major Perioperative Complications for Prolapse Surgery.

Journal Article Urogynecology (Phila) · January 16, 2024 IMPORTANCE: Obesity adds complexity to the decision of surgical approach for pelvic organ prolapse; data regarding perioperative complications are needed. OBJECTIVE: The aim of the study was to evaluate associations of body mass index (BMI) and surgical ap ... Full text Link to item Cite

Management of partial Müllerian agenesis: staged McIndoe procedure for the creation of a neovagina and utero-neovaginal unification.

Journal Article Int Urogynecol J · August 2023 INTRODUCTION: The objectives of this video are to provide a brief overview of Müllerian agenesis, discuss a case of partial vaginal agenesis with a functional uterus, and present the steps of a staged McIndoe procedure for the creation of a neovagina and u ... Full text Link to item Cite

A New Dimension in Pessary Care.

Journal Article Urogynecology (Phila) · June 1, 2023 Full text Link to item Cite

Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence.

Journal Article NPJ Regen Med · September 29, 2022 Urinary incontinence afflicts up to 40% of adult women in the United States. Stress urinary incontinence (SUI) accounts for approximately one-third of these cases, precipitating ~200,000 surgical procedures annually. Continence is maintained through the in ... Full text Link to item Cite

Three-Dimensional-Printed Vaginal Molds for Use After McIndoe Neovagina Creation.

Journal Article Obstet Gynecol · August 1, 2022 BACKGROUND: Surgical vaginoplasty is a highly successful treatment for congenital absence of the vagina. One key to long-term success is the use of an appropriate vaginal mold in the immediate postoperative period. We present the use of a three-dimensional ... Full text Link to item Cite

Vesicouterine Fistula: A Robotic Approach.

Journal Article Int Urogynecol J · June 2022 INTRODUCTION AND HYPOTHESIS: This video demonstrates surgical repair of a vesicouterine fistula via a robotic, uterine-sparing approach. METHODS: In this video, we present a vesicouterine fistula, which occurred after cesarean delivery. The patient present ... Full text Link to item Cite

Postoperative Urinary Incontinence in Diabetic Patients Undergoing Pelvic Reconstructive Surgery.

Journal Article Female Pelvic Med Reconstr Surg · June 1, 2022 IMPORTANCE: Diabetes is an independent risk factor for urinary incontinence, and its impact on rates of postoperative incontinence after pelvic reconstructive surgery remains unexplored. OBJECTIVE: The aim of the study was to compare the incidence of posto ... Full text Link to item Cite

Management of advanced prolapse including a bowel obstruction: expanding the role of transvaginal surgery.

Journal Article Int Urogynecol J · January 2022 INTRODUCTION AND HYPOTHESIS: We reviewed a case of concomitant advanced pelvic organ prolapse and partial small bowel obstruction managed via transvaginal small bowel resection and native tissue prolapse repair. METHODS: The patient is an 82-year-old woman ... Full text Link to item Cite

Surgical Outcomes in Urogynecology-Assessment of Perioperative and Postoperative Complications Relative to Preoperative Hemoglobin A1c-A Fellows Pelvic Research Network Study.

Journal Article Female Pelvic Med Reconstr Surg · January 1, 2022 OBJECTIVES: Poor control of diabetes mellitus is a known predictor of perioperative and postoperative complications. No literature to date has established a hemoglobin A1c (HbA1c) cutoff for risk stratification in the urogynecology population. We sought to ... Full text Link to item Cite

Exosome-Induced Vaginal Tissue Regeneration in a Porcine Mesh Exposure Model.

Journal Article Female Pelvic Med Reconstr Surg · October 1, 2021 OBJECTIVES: The purpose of this study was to explore the utility of an injectable purified exosome product derived from human apheresis blood to (1) augment surgical closure of vaginal mesh exposures, and (2) serve as a stand-alone therapy for vaginal mesh ... Full text Link to item Cite

Teaching the art of LeFort colpocleisis: a moderate-fidelity, low-cost simulation model.

Journal Article Int Urogynecol J · August 2021 The objective was to demonstrate the build and use of a low-cost, moderate-fidelity simulation model for LeFort colpocleisis. We a present a video demonstrating the creation of a LeFort colpocleisis model, the mounting of this model to a pre-existing vagin ... Full text Link to item Cite

Impact of Repeat Dosing and Mesh Exposure Chronicity on Exosome-Induced Vaginal Tissue Regeneration in a Porcine Mesh Exposure Model.

Journal Article Female Pelvic Med Reconstr Surg · March 1, 2021 OBJECTIVE: The aim of the study was to compare vaginal wound healing after exosome injection in a porcine mesh exposure model with (1) single versus multiple dose regimens and (2) acute versus subacute exposure. METHODS: Six 80-kg Yorkshire-crossed swine e ... Full text Link to item Cite

Perioperative Complications in Minimally Invasive Sacrocolpopexy Versus Transvaginal Mesh in the Management of Pelvic Organ Prolapse: Analysis of a National Multi-institutional Dataset.

Journal Article Female Pelvic Med Reconstr Surg · February 1, 2021 OBJECTIVES: The objective of this study was to evaluate perioperative complications in women who underwent minimally invasive sacrocolpopexy (MISC) versus mesh-augmented vaginal repair (vaginal mesh) for pelvic organ prolapse. METHODS: We identified patien ... Full text Link to item Cite

Surgical management of stress urinary incontinence following traumatic pelvic injury.

Journal Article Int Urogynecol J · January 2021 INTRODUCTION AND HYPOTHESIS: The objective was to discuss the evaluation and management of stress urinary incontinence (SUI) following traumatic pelvic injury by use of a video case. METHODS: We present a patient with severe SUI following pelvic trauma and ... Full text Link to item Cite

Surgical management of mid- and upper-vaginal constriction rings

Conference AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY · 2021 Cite

Management of Vaginal Mesh Exposures Following Female Pelvic Reconstructive Surgery.

Journal Article Curr Urol Rep · October 30, 2020 PURPOSE OF REVIEW: To discuss considerations and current evidence for the diagnosis and management of vaginal mesh exposures following female mesh-augmented anti-incontinence and pelvic organ prolapse surgery. RECENT FINDINGS: Since the introduction of mes ... Full text Link to item Cite

Ultrasound vibro-elastography for assessing mechanical properties of porcine reproductive tissues in an ex vivo model.

Journal Article Clin Biomech (Bristol, Avon) · August 2020 BACKGROUND: The aim of this study was to use ultrasound vibro-elastography (UVE) for measuring surface wave speed and assessing mechanical properties of ex vivo porcine reproductive tissues, including the uterus, bladder, cornua and cervix. METHODS: In UVE ... Full text Link to item Cite

Teaching learners to raise the roof: a vaginal surgery simulator for apical suspension.

Journal Article Int Urogynecol J · October 2019 INTRODUCTION AND HYPOTHESIS: The objective was to discuss the importance of apical suspension following vaginal hysterectomy and demonstrate a surgical model to aide in educating learners on a variety of apical suspension procedures. METHODS: Rates of pelv ... Full text Link to item Cite

Randomized Controlled Trial to Assess the Impact of Intraurethral Lidocaine on Urodynamic Voiding Parameters.

Journal Article Female Pelvic Med Reconstr Surg · 2019 OBJECTIVES: The aim of the study was to determine whether intraurethral anesthesia decreases voiding efficiency (VE; voided volume/(voided volume + residual volume)) and impacts other urodynamic parameters in healthy female volunteers during urodynamic stu ... Full text Link to item Cite

Same-Day Discharge After Robotic-Assisted Sacrocolpopexy.

Journal Article Female Pelvic Med Reconstr Surg · 2019 OBJECTIVE: The aim of the study was to compare unplanned postoperative encounters in women discharged same day versus later after robotic-assisted sacrocolpopexy (RA-SCP). METHODS: This is a retrospective cohort study of women who underwent RA-SCP at a ter ... Full text Link to item Cite

EXOSOME-INDUCED VAGINAL EPITHELIAL REGENERATION IN A PORCINE MESH EXPOSURE MODEL

Conference INTERNATIONAL UROGYNECOLOGY JOURNAL · 2019 Cite

The Evaluation of Baseline Physical Function and Cognition in Women Undergoing Pelvic Floor Surgery.

Journal Article Female Pelvic Med Reconstr Surg · 2016 OBJECTIVES: Physical and cognitive function impairments are associated with increased perioperative morbidity; however, limited data exist regarding these parameters in women planning pelvic floor surgery. Thus, our goal was to assess baseline physical fun ... Full text Link to item Cite

Impact of anticholinergic load on bladder function.

Journal Article Int Urogynecol J · April 2015 INTRODUCTION AND HYPOTHESIS: Our aim was to evaluate the impact of anticholinergic load on urinary retention based on postvoid residual (PVR) on micturition study. Secondary objectives were to assess the effect of anticholinergic load on other urodynamic p ... Full text Link to item Cite

THE IMPACT OF ANTICHOLINERGIC LOAD ON BLADDER FUNCTION

Conference INTERNATIONAL UROGYNECOLOGY JOURNAL · 2014 Cite

Effect of virtual reality on time perception in patients receiving chemotherapy.

Journal Article Support Care Cancer · April 2011 PURPOSE: Virtual reality (VR) during chemotherapy has resulted in an elapsed time compression effect, validating the attention diversion capabilities of VR. Using the framework of the pacemaker-accumulator cognitive model of time perception, this study exp ... Full text Link to item Cite