Scholars@Duke
Alessandro Martinino

Selected Publications

Global 30-Day Morbidity and Mortality of Primary Bariatric Surgery Combined with Another Procedure: The BLEND Study.

Journal Article Obesity surgery · November 2024 BackgroundNo robust data are available on the safety of primary bariatric and metabolic surgery (BMS) alone compared to primary BMS combined with other procedures.ObjectivesThe objective of this study is to collect a 30-day mortality and ... Full text Cite

Animal Models Within Surgical Simulation: A Novel Approach to the 3 Rs.

Journal Article J Surg Res · November 2024 INTRODUCTION: Development of technical skills is a vital component of surgical residency. The use of animal tissues for operative simulation leads to both the loss of animal life and financial costs for the institution. We hypothesized that maximizing tiss ... Full text Link to item Cite

The Gut Microbiome and Symptom Burden After Kidney Transplantation: An Overview and Research Opportunities.

Journal Article Biological research for nursing · October 2024 Many kidney transplant recipients continue to experience high symptom burden despite restoration of kidney function. High symptom burden is a significant driver of quality of life. In the post-transplant setting, high symptom burden has been linked to nega ... Full text Cite

Disparities in Bariatric Surgery Outcomes: A Regional Analysis.

Journal Article Obesity surgery · October 2024 PurposeThe success of metabolic and bariatric surgery (MBS) is impacted by significant pre-surgical attrition rates and poor postoperative follow-up. This study focused on geographic variations in attrition rates and surgical outcomes for MBS prac ... Full text Cite

Textbook Outcomes in Solid Transplantation: A Systematic Review.

Journal Article Transplant Direct · October 2024 BACKGROUND: The concept of TO is expanding across various surgical disciplines to establish a standardized, comprehensive quality benchmark. Traditional metrics such as 1-y patient and graft survival have been key for evaluating transplant program performa ... Full text Link to item Cite

The ASGLOS Study: A global survey on how predatory journals affect scientific practice.

Journal Article Developing world bioethics · September 2024 Predatory journals and conferences are an emerging problem in scientific literature as they have financial motives, without guaranteeing scientific quality and exposure. The main objective of the ASGLOS project is to investigate the predatory e-email chara ... Full text Cite

Living Donor Intestinal Transplantation.

Journal Article Gastroenterology clinics of North America · September 2024 This study explores intestinal transplantation (ITx) as a viable treatment option for intestinal failure (IF). Historical development, donor and recipient considerations, surgical techniques, immunosuppression, and outcomes, are reviewed with particular em ... Full text Cite

Analyzing the Impact of CIT on the Largest Reported Cohort of Robotic Kidney Transplantation From the Deceased Donors.

Journal Article Transplantation direct · September 2024 BackgroundRobotic-assisted kidney transplant (RAKT) has proven to be a successful approach for patients with morbid obesity and more centers are encouraged to apply robotic approach also for deceased donor kidney transplantation. Prolonged cold is ... Full text Cite

Global 30-day morbidity and mortality of surgery for perforated peptic ulcer: GRACE study.

Journal Article Surgical endoscopy · August 2024 BackgroundThere is little international data on morbidity and mortality of surgery for perforated peptic ulcer (PPU). This study aimed to understand the global 30-day morbidity and mortality of patients undergoing surgery for PPU and to identify v ... Full text Cite

Single-center retrospective assessment of robotic-assisted simultaneous pancreas-kidney transplants: Exploring clinical utility.

Journal Article American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · June 2024 The diabetic population is witnessing a rise in obesity rates, creating specific hurdles for individuals seeking pancreas transplantation because they are frequently disqualified due to their elevated body weight. Introducing a robotic-assisted approach to ... Full text Cite

Indications for Multivisceral Transplantation: A Systematic Review.

Journal Article Gastroenterology clinics of North America · June 2024 Consensus remains elusive in the definition and indications of multivisceral transplantation (MVT) within the transplant community. MVT encompasses transplantation of all organs reliant on the celiac artery axis and the superior mesenteric artery in differ ... Full text Cite

Sleeve Migration Following Sleeve Gastrectomy: A Systematic Review of Current Literature.

Journal Article Obesity surgery · June 2024 Sleeve gastrectomy (SG) is the most frequently performed bariatric procedure worldwide. The incidence and consequences of sleeve migration (SM) are not clearly understood. There is no clear consensus on appropriate measures to reduce the risk of SM. This s ... Full text Cite

Robotic Surgical Techniques in Transplantation: A Comprehensive Review

Journal Article Transplantology · June 1, 2024 In the field of surgery, the idea of performing organ transplants in a minimally invasive fashion has always been a significant technical challenge. The advent of the robotic approach facilitated the overcoming of difficulties in highly complex surgical pr ... Full text Cite

New Frontiers in Pancreatic Cancer Management: Current Treatment Options and the Emerging Role of Neoadjuvant Therapy.

Journal Article Medicina (Kaunas, Lithuania) · June 2024 Pancreatic ductal adenocarcinoma (PDAC) ranks among the 15 most prevalent cancers globally, characterized by aggressive growth and late-stage diagnosis. Advances in imaging and surgical techniques have redefined the classification of pancreatic PDAC into r ... Full text Cite

Clinical outcomes of intestinal transplant recipients receiving maintenance basiliximab, sublingual tacrolimus and prednisone: A case series.

Journal Article Human immunology · May 2024 IntroductionIntestinal transplantation poses a unique challenge in the field of solid organ transplantation. The combination of tacrolimus and prednisone stands as the foundational cornerstone of maintenance immunosuppression in the field of intes ... Full text Cite

Surgical Resection in Colorectal Liver Metastasis: An Umbrella Review.

Journal Article Cancers · May 2024 Surgical resection is the gold standard for treating synchronous colorectal liver metastases (CRLM). The resection of the primary tumor and metastatic lesions can follow different sequences: "simultaneous", "bowel-first", and "liver-first". Conservative ap ... Full text Cite

Use of Fluorescence Imaging in Liver Transplant Surgery

Journal Article Journal of Clinical Medicine · May 1, 2024 Liver transplant surgery is a complex procedure that demands high knowledge of surgical anatomy and the precise recognition and preservation of structures. To address this, the use of fluorescence imaging has facilitated the identification of anatomical st ... Full text Cite

A systematic review on laparoscopic subtotal cholecystectomy for difficult gallbladders: a lifesaving bailout or an incomplete operation?

Journal Article Annals of the Royal College of Surgeons of England · March 2024 IntroductionLaparoscopic subtotal cholecystectomy (LSTC) is a bailout procedure that is undertaken when it is not safe to proceed with a laparoscopic total cholecystectomy owing to dense adhesions in Calot's triangle. The main aim of this review w ... Full text Cite

Robotic Vascular Resection in Pancreatic Ductal Adenocarcinoma: A Systematic Review.

Journal Article Journal of clinical medicine · March 2024 (1) Background: This study comprehensively compared robotic pancreatic surgery with vascular resection (RPS-VR) to other surgical procedures in the treatment of pancreatic ductal adenocarcinoma (PDAC). (2) Methods: A systematic review of rele ... Full text Cite

Exploring the Multifaceted Landscape of MASLD: A Comprehensive Synthesis of Recent Studies, from Pathophysiology to Organoids and Beyond.

Journal Article Biomedicines · February 2024 Non-alcoholic fatty liver disease (NAFLD) is a widespread contributor to chronic liver disease globally. A recent consensus on renaming liver disease was established, and metabolic dysfunction-associated steatotic liver disease, MASLD, was chosen as the re ... Full text Cite

Feasibility of robotic cholecystectomy at an academic center with a young robotic surgery program: a retrospective cohort study with umbrella review.

Journal Article Journal of robotic surgery · February 2024 Laparoscopic cholecystectomy (LC) has been standard of care for surgical treatment of benign gallbladder pathology for decades. With the advent of robotic surgical technology, robotic cholecystectomy (RC) has gained attention as an alternative to conventio ... Full text Cite

Unraveling Biomarker Signatures in Triple-Negative Breast Cancer: A Systematic Review for Targeted Approaches.

Journal Article International journal of molecular sciences · February 2024 Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast cancer, marked by poor outcomes and dismal prognosis. Due to the absence of targetable receptors, chemotherapy still represents the main therapeutic option. Therefore, cu ... Full text Cite

30-day Morbidity and Mortality after Cholecystectomy for Benign Gallbladder Disease (AMBROSE): A Prospective, International Collaborative Cohort Study.

Journal Article Annals of surgery · February 2024 ObjectiveThis study aimed to assess 30-day morbidity and mortality rates following cholecystectomy for benign gallbladder disease and identify the factors associated with complications.Summary background dataAlthough cholecystectomy is co ... Full text Cite

Liver transplantation vs liver resection in HCC: promoting extensive collaborative research through a survival meta-analysis of meta-analyses

Journal Article Frontiers in Oncology · January 1, 2024 Background: HCC is a major global health concern, necessitating effective treatment strategies. This study conducts a meta-analysis of meta-analyses comparing liver resection (LR) and liver transplantation (LT) for HCC. Methods: The systematic review inclu ... Full text Cite

The Role of Colon in Isolated Intestinal Transplantation: Description of 4 Cases.

Journal Article International journal of surgical oncology · January 2024 Intra-abdominal desmoid tumors are a rare and complex clinical problem. These tumors are locally invasive, and surgical ablation represents the mainstay of treatment. When localized at the root of the mesentery, their resection may require extensive excisi ... Full text Cite

Timing Considerations for Sleeve Gastrectomy in Kidney Transplant Patients: A Single Center Evaluation.

Journal Article Transplant international : official journal of the European Society for Organ Transplantation · January 2024 Current scientific literature is deficient in detailing the optimal timing for conducting bariatric surgery in relation to kidney transplantation. In this study, we performed a retrospective evaluation of kidney transplant recipients with BMI >35 kg/m ... Full text Cite

Laparoscopic versus open liver resection for colorectal liver metastasis: an umbrella review

Journal Article Frontiers in Oncology · January 1, 2024 Introduction: This study comprehensively compared laparoscopic liver resection (LLR) to open liver resection (OLR) in treating colorectal cancer liver metastasis (CRLM). Methods: A systematic review of relevant literature was conducted to assess a range of ... Full text Cite

SICOB Italian clinical practice guidelines for the surgical treatment of obesity and associated diseases using GRADE methodology on bariatric and metabolic surgery

Journal Article Updates in Surgery · January 1, 2024 Obesity is a chronic disease associated with increased morbidity and mortality and reduced quality of life. Pharmacotherapy can be associated with life style changes in increasing and maintaining weight loss and ameliorating obesity-related complications a ... Full text Cite

Epicardial Adipose Tissue Changes After Bariatric and Metabolic Surgery: a Systematic Review and Meta-analysis.

Journal Article Obesity surgery · November 2023 Epicardial adipose tissue (EAT) is a visceral fat depot located between the myocardium and visceral epicardium. Emerging evidence suggests that excessive EAT is linked to increased risk of cardiovascular conditions and other metabolic diseases. A literatur ... Full text Cite

Combined small bowel and pancreas transplant

Journal Article Minerva Surgery · October 1, 2023 Full text Cite

Empowering liver transplantation: The role of minimally invasive hepatectomy in advancing living donation.

Journal Article Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · October 2023 Full text Cite

FCH-PET/CT in Primary Hyperparathyroidism With Discordant/Negative MIBI Scintigraphy and Ultrasonography.

Journal Article The Journal of clinical endocrinology and metabolism · July 2023 ContextThe contribution of [18F]F-fluorocholine (FCH)-positron emission tomography (PET)/computed tomography (CT) in normocalcemic primary hyperparathyroidism (nPHPT) remains unknown.ObjectiveTo evaluate the sensitivity and specificity of ... Full text Cite

The Role of mTOR Inhibitors after Liver Transplantation for Hepatocellular Carcinoma.

Journal Article Current oncology (Toronto, Ont.) · June 2023 Liver transplantation is a treatment option for nonresectable patients with early-stage HCC, with more significant advantages when Milan criteria are fulfilled. An immunosuppressive regimen is required to reduce the risk of graft rejection after transplant ... Full text Cite

Robotic kidney transplantation from deceased donors: A single-center experience.

Journal Article American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · May 2023 Robotic-assisted kidney transplant (RAKT) has proven to be a successful approach for patients with elevated body mass index (BMI). To date, a paucity of studies comprehensively analyzing the clinical outcomes of RAKT by using the grafts from deceased donor ... Full text Cite

Young nursing and medical students' knowledge and attitudes towards sexuality and contraception in two spanish universities: an inferential study.

Journal Article BMC medical education · April 2023 BackgroundLiving safely sexuality and without risk to one's health is an international priority. The youth age group has specific characteristics that make it a particularly vulnerable group for adverse consequences such as unwanted pregnancies or ... Full text Cite

The Role of Growth Hormone and Insulin Growth Factor 1 in the Development of Non-Alcoholic Steato-Hepatitis: A Systematic Review.

Journal Article Cells · February 2023 Diabetic and obese patients have a high prevalence of non-alcoholic fatty liver disease (NAFLD). This condition groups a spectrum of conditions varying from simple steatosis to non-alcoholic steatohepatitis (NASH), with or without fibrosis. Multiple factor ... Full text Cite

The use of the T-tube in biliary tract reconstruction during orthotopic liver transplantation: An umbrella review.

Journal Article Transplantation reviews (Orlando, Fla.) · December 2022 Biliary complications are one of the main concerns after liver transplantation, and to avoid these, the use of a T-tube has been advocated in biliary reconstruction. Most liver transplantation centres perform a biliary anastomosis without a T-tube to avoid ... Full text Cite

Development of the Italian Clinical Practice Guidelines on Bariatric and Metabolic Surgery: Design and Methodological Aspects.

Journal Article Nutrients · December 2022 Development of the Italian clinical practice guidelines on bariatric and metabolic surgery, as well as design and methodological aspects.BackgroundObesity and its complications are a growing problem in many countries. Italian Society of Bariatric ... Full text Cite

V-009 ROBOTIC UMBILICAL HERNIA REPAIR WITH RETRORECTUS SUBLAY MESH AND PLICATION OF RECTUS DIASTASIS VIA THE TRANSABDOMINAL PREPERITONEAL (TAPP) APPROACH

Journal Article British Journal of Surgery · October 13, 2022 AbstractAimUmbilical hernias and rectus diastasis can greatly reduce patients’ quality of life, especially in this patient who is a pr ... Full text Cite

Artificial Intelligence in the Diagnosis of Hepatocellular Carcinoma: A Systematic Review.

Journal Article Journal of clinical medicine · October 2022 Hepatocellular carcinoma ranks fifth amongst the most common malignancies and is the third most common cause of cancer-related death globally. Artificial Intelligence is a rapidly growing field of interest. Following the PRISMA reporting guidelines, we con ... Full text Cite

Predictors of morbidity in revisional bariatric surgery and bariatric emergencies at an MBSAQIP-accredited community hospital.

Journal Article World journal of emergency surgery : WJES · October 2022 IntroductionBariatric surgery revisions and emergencies are associated with higher morbidity and mortality compared to primary bariatric surgery. No formal outcome benchmarks exist that distinguish MBSAQIP-accredited centers in the community from ... Full text Cite

Perforated marginal ulcer after gastric bypass for obesity: a systematic review.

Journal Article Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · September 2022 Marginal ulcers are a recognized complication of gastric bypass procedures for obesity. Perforated marginal ulcer (PMU) is a life-threatening complication of marginal ulcers. We performed a systematic review to understand the presentation, management, and ... Full text Cite

Robotic Complex Abdominal Wall Reconstruction: The Evolution of Component Separation

Chapter · June 1, 2022 From the first description of the component separation technique in the literature at the end of the twentieth century to the current state of complex abdominal wall reconstruction, this rapidly evolving field of General Surgery has advanced at an ... Full text Cite

Preparedness and satisfaction of European medical students: development and validation of the EUSPSQ.

Journal Article La Clinica terapeutica · May 2022 ContextIn Europe, during an era of globalization in which traveling and studying abroad is becoming easier and more affordable, an open question remains on whether different European medical schools educate students with a dissimilar level of prep ... Full text Cite

Trends in Gender Diversity in the Field of Otolaryngology-Head and Neck Surgery in Canada.

Journal Article JAMA otolaryngology-- head & neck surgery · April 2022 Full text Cite

Epicardial adipose tissue, obesity, and the occurrence of atrial fibrillation: an overview of pathophysiology and treatment methods.

Journal Article Expert review of cardiovascular therapy · April 2022 IntroductionObesity is a chronic disease, which has significant health consequences and is a staggering burden to health care systems. Obesity can have harmful effects on the cardiovascular system, including heart failure, hypertension, coronary h ... Full text Cite

Bariatric surgery on social media: A cross-sectional study.

Journal Article Obesity research & clinical practice · March 2022 IntroductionBariatric Surgery (BS) represents a viable option for the treatment of obesity and its risks. Nevertheless, it is still being underused by the eligible patient population because of the general lack of information, false beliefs, and t ... Full text Cite

ART Outcomes After Hysteroscopic Proximal Tubal Occlusion Versus Laparoscopic Salpingectomy for Hydrosalpinx Management in Endometriosis Patients.

Journal Article Reproductive sciences (Thousand Oaks, Calif.) · February 2022 The objective of this paper is to compare assisted reproductive technology (ART) cumulative live birth rates after hysteroscopic proximal tubal occlusion and laparoscopic salpingectomy in endometriosis patients, for management of hydrosalpinx. This is an o ... Full text Cite

Response to: "Recent advances in the mechanisms underlying the beneficial effects of bariatric and metabolic surgery".

Journal Article Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · February 2022 Full text Cite

Gender Discrimination, Quality of Training, and Job Satisfaction for Surgeons in Italy.

Journal Article Journal of the American College of Surgeons · February 2022 Full text Cite

Burden of liver disease progression in hospitalized patients with type 2 diabetes mellitus.

Journal Article Journal of hepatology · February 2022 Background & aimsThere are uncertainties regarding the burden of liver disease in patients with type 2 diabetes (T2D). Thus, we aimed to quantify the burden of liver disease, identify risk factors, and estimate attributable risks in patients with ... Full text Cite

O-BN02 Laparoscopic subtotal cholecystectomy for difficult gallbladders: A lifesaving bailout or an incomplete operation? A systematic review

Journal Article British Journal of Surgery · December 15, 2021 AbstractBackgroundCholecystectomy is one of the commonest abdominal operations performed worldwide. Sometimes, the operation can be te ... Full text Cite

The rise of the hepatitis E virus.

Journal Article Journal of hepatology · December 2021 Full text Cite

Healthy habits and Instagram: A Cross - Sectional study.

Journal Article La Clinica terapeutica · May 2021 AbstractSocial media could be considered as an interesting complementary tool to the public health domain. Although the literature has studied in detail the efficacy of some of these platforms, it is unclear whether Instagram® can play a role in t ... Full text Cite

Fetoscopic laser ablation in twin-to-twin transfusion syndrome: tips for counselling.

Journal Article Minerva obstetrics and gynecology · April 2021 Twin-to-twin transfusion syndrome (TTTS) is a serious complication that affects approximately 10-15% of monochorionic twin pregnancies. The most important role for the development of this condition is the presence of an unbalanced flow through the inter-tw ... Full text Cite

Study Protocol of the PreFiPS Study: Prevention of Postoperative Pancreatic Fistula by Somatostatin Compared With Octreotide, a Prospective Randomized Controlled Trial.

Journal Article Frontiers in medicine · January 2020 Background: Pancreatic fistula (PF), i. e., a failure of the pancreatic anastomosis or closure of the remnant pancreas after distal pancreatectomy, is one of the most feared complications after pancreatic surgery. PF is also one of the most common c ... Full text Cite