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Alexandra Jordan Horne

Assistant Professor of Medicine
Medicine, General Internal Medicine
508 Fulton Street, Durham, NC 27705

Selected Publications

Prevalence and Risk Factors for Low Bone Mineral Density in Adults With Cystic Fibrosis

Journal Article JBMR Plus · November 1, 2022 Single-center studies have suggested that up to 70% of adults with cystic fibrosis (CF) have lower than expected bone mineral density (BMD), substantially higher than the 25% prevalence reported from national registries. We determined the prevalence of low ... Full text Cite

Rosai-Dorfman Disease Presenting as Massive Mediastinal Lymphadenopathy in an Elderly Man

Journal Article Annals of Internal Medicine Clinical Cases · October 1, 2022 We present a patient case of a 73-year-old man with new-onset substernal chest pain and B symptoms, found on computed tomography imaging to have massive mediastinal lymphadenopathy of more than 6 cm. Positron emission tomography imaging revealed fluorodeox ... Full text Cite

Cavitary lung nodules as an extraintestinal manifestation of ulcerative colitis.

Journal Article BMJ Case Rep · September 23, 2022 A man in his 30s with ulcerative colitis (UC) on immunosuppressive agents and extensive travel history presented with subacute dyspnoea and dry cough. CT of the chest demonstrated numerous cavitary pulmonary nodules. An extensive infectious, malignant and ... Full text Link to item Cite

Relating Sensory, Cognitive, and Neural Factors to Older Persons' Perceptions about Happiness: An Exploratory Study.

Journal Article J Aging Res · 2018 Despite increased rates of disease, disability, and social losses with aging, seniors consistently report higher levels of subjective well-being (SWB), a construct closely related to happiness, than younger adults. In this exploratory study, we utilized an ... Full text Open Access Link to item Cite

Expression of a bacterial catalase in a strictly anaerobic methanogen significantly increases tolerance to hydrogen peroxide but not oxygen.

Journal Article Microbiology (Reading) · February 2014 Haem-dependent catalase is an antioxidant enzyme that degrades H2O2, producing H2O and O2, and is common in aerobes. Catalase is present in some strictly anaerobic methane-producing archaea (methanogens), but the importance of catalase to the antioxidant s ... Full text Link to item Cite

Assessment of the oxidant tolerance of Methanosarcina acetivorans.

Journal Article FEMS Microbiol Lett · June 2013 All methane-producing Archaea (methanogens) are strict anaerobes, but the majority of species are tolerant to oxidants. Methanosarcina species are important environmental and industrial methanogens as they are one of only two genera capable of producing me ... Full text Link to item Cite