Skip to main content

Ali Reza Zomorodi

Professor of Neurosurgery
Neurosurgery
Box 31194 Med Ctr, Durham, NC 27710
Dept of Neurosurgery, Durham, NC 27710

Selected Publications


Safety and Feasibility of Steroid-Eluting Stent as a Bolster in Endoscopic Anterior Skull Base Reconstruction.

Journal Article Ann Otol Rhinol Laryngol · January 2024 BACKGROUND: With a rising incidence of cerebrospinal fluid (CSF) leaks, endoscopic endonasal CSF leak repair is increasingly performed. Current approaches utilize a variety of materials including free mucosal grafts and vascularized flaps, but post-op leak ... Full text Link to item Cite

Comparative outcomes of middle meningeal artery embolization with statins versus embolization alone in the treatment of chronic subdural hematoma: a systematic review and meta-analysis.

Journal Article Neurosurg Rev · October 3, 2023 Chronic subdural hematoma (cSDH) is common among the elderly, with surgical evacuation as a prevalent treatment, facing recurrence rates up to 30%. Recently, middle meningeal artery embolization (MMAE) has emerged as a promising approach, offering reduced ... Full text Link to item Cite

Use of Tympanostomy T-Tube for Endoscopic Endonasal Marsupialization of Small Rathke's Cleft Cysts: A Case Series.

Journal Article J Neurol Surg B Skull Base · August 2023 Objectives  This article describes a novel technique implementing the use of a tympanostomy t-tube to provide long-term marsupialization of small Rathke's cleft cysts (RCCs). Design  A retrospective review of electronic medical records was performed to col ... Full text Link to item Cite

A Nationwide Analysis of Aneurysmal Subarachnoid Hemorrhage Mortality, Complications, and Health Economics in the USA.

Journal Article Transl Stroke Res · June 2023 Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating neurological condition. Endovascular coiling or surgical clipping have equivocal success rates, but relatively little is known regarding the health economics and complications of these procedures a ... Full text Link to item Cite

Revisiting flow augmentation bypass for cerebrovascular atherosclerotic vaso-occlusive disease: Single-surgeon series and review of the literature.

Journal Article PLoS One · 2023 OBJECTIVE: Despite advances in the nonsurgical management of cerebrovascular atherosclerotic steno-occlusive disease, approximately 15-20% of patients remain at high risk for recurrent ischemia. The benefit of revascularization with flow augmentation bypas ... Full text Link to item Cite

Approaches to the Cerebellopontine Angle

Chapter · January 1, 2023 The cerebellopontine angle (CPA) is formed by the petrosal cerebellar surface, middle cerebellar peduncle, lateral pons, petrosal surface of the petrous bone, and clival portion of the occipital bone. While only accounting for 10–15% of intracranial tumors ... Full text Cite

Retrolabyrinthine transsigmoid approach to complex parabrainstem tumors in the posterior fossa.

Journal Article J Neurosurg · April 1, 2022 OBJECTIVE: The surgical management of large and complex tumors of the posterior fossa poses a formidable challenge in neurosurgery. The standard retrosigmoid craniotomy approach has been performed at most neurosurgical centers; however, the retrosigmoid ap ... Full text Link to item Cite

Long-Term Outcomes for Patients With Atypical or Malignant Meningiomas Treated With or Without Radiation Therapy: A 25-Year Retrospective Analysis of a Single-Institution Experience.

Journal Article Adv Radiat Oncol · 2022 PURPOSE: Atypical (World Health Organization [WHO] grade 2) and malignant (WHO grade 3) meningiomas have high rates of local recurrence, and questions remain about the role of adjuvant radiation therapy (RT) for patients with WHO grade 2 disease. These pat ... Full text Link to item Cite

Koos grade IV vestibular schwannomas: considerations on a consecutive series of 60 cases-searching for the balance between preservation of function and maximal tumor removal.

Journal Article Neurosurg Rev · December 2021 Koos grade IV vestibular schwannomas (VS) (maximum diameter > 3 cm) compress the brainstem and displace the fourth ventricle. Microsurgical resection with attention to the right balance between preservation of function and maximal tumor removal is the trea ... Full text Link to item Cite

Safety of the APOLLO Onyx delivery microcatheter for embolization of brain arteriovenous malformations: results from a prospective post-market study.

Journal Article J Neurointerv Surg · October 2021 BACKGROUND: Catheter retention and difficulty in retrieval have been observed during embolization of brain arteriovenous malformations (bAVMs) with the Onyx liquid embolic system (Onyx). The Apollo Onyx delivery microcatheter (Apollo) is a single lumen cat ... Full text Link to item Cite

Neurosurgical management of petrous bone lesions: classification system and selection of surgical approaches.

Journal Article Acta Neurochir (Wien) · October 2021 BACKGROUND: Surgery of petrous bone lesions (PBLs) is challenging for neurosurgeons. Selection of the surgical approach is an important key for success. In this study, the authors present an anatomical classification for PBLs that has been used by our grou ... Full text Link to item Cite

Petrous bone lesions: surgical implementation and outcomes of extradural subtemporal approach.

Journal Article Acta Neurochir (Wien) · October 2021 BACKGROUND: Petrous bone lesions (PBLs) are rare with few reports in the neurosurgical literature. In this study, the authors describe our current technique of extradural subtemporal approach (ESTA). The objective of this study was to evaluate the role and ... Full text Link to item Cite

How I do it: total resection of a giant sphenoclinoidal meningioma with normalization of near blind vision.

Journal Article Acta Neurochir (Wien) · September 2021 BACKGROUND: Resection of giant sphenoclinoidal meningiomas (SCLM) remains difficult. We discuss a patient presenting with right eye near blindness who underwent total removal of a giant SCLM, resulting in normal vision and no recurrence. METHOD: Utilizing ... Full text Link to item Cite

Management of unruptured incidentally found intracranial saccular aneurysms.

Journal Article Neurosurg Rev · August 2021 Unruptured intracranial saccular aneurysms occur in 3-5% of the general population. As the use of diagnostic medical imaging has steadily increased over the past few decades with the increased availability of computed tomography (CT) and magnetic resonance ... Full text Link to item Cite

Extradural anterior temporal fossa approach to the paranasal sinuses, nasal cavities through the anterolateral and anteromedial triangles: Combined microscopic and endoscopic strategy.

Journal Article Acta Neurochir (Wien) · August 2021 OBJECTIVE: To demonstrate the utility and limitations of the extradural endoscopic-assisted anterior temporal fossa approach to the pterygopalatine fossa (PPF), infratemporal fossa (ITF), paranasal sinuses (PS), parapharyngeal region (PPR), nasal cavities ... Full text Link to item Cite

Flow diversion of fusiform intracranial aneurysms.

Journal Article Neurosurg Rev · June 2021 Fusiform aneurysms are less common than saccular aneurysms, but have higher associated mortality and rebleeding rates. Recently, flow diversion has emerged as a possible treatment option. The purpose of this study was to determine the safety and efficacy o ... Full text Link to item Cite

Associations between Features of External Ventricular Drain Management, Disposition, and Shunt Dependence

Journal Article Journal of Neuroanaesthesiology and Critical Care · March 1, 2021 Background In the United States, nearly 25,000 patients annually undergo percutaneous ventriculostomy for the management of increased intracranial pressure with little consensus on extraventricular drain management. To characterize relationships between ex ... Full text Open Access Cite

Olfactory-Specific Quality of Life Outcomes after Endoscopic Endonasal Surgery of the Sella.

Journal Article Allergy & rhinology (Providence, R.I.) · January 2021 ObjectiveTo assess olfactory outcomes as measured by an olfactory-specific quality of life (QOL) questionnaire in patients undergoing EESBS for sellar lesions.DesignRetrospective case series.SettingTertiary academic medical cente ... Full text Cite

STA-enhanced vascularized galeal flap for revascularization of moyamoya disease: technical report.

Journal Article Acta Neurochir (Wien) · August 2020 BACKGROUND: A variety of revascularization techniques have been reported for the management of moyamoya disease to prevent risks of stroke. STA (superficial temporal artery)-MCA (middle cerebral artery) microanastomosis, single or double bypass, with tempo ... Full text Link to item Cite

Safety and Feasibility of Steroid-Eluting Stent as a Bolster in Endoscopic Anterior Skull Base Reconstruction.

Journal Article Ann Otol Rhinol Laryngol · January 2024 BACKGROUND: With a rising incidence of cerebrospinal fluid (CSF) leaks, endoscopic endonasal CSF leak repair is increasingly performed. Current approaches utilize a variety of materials including free mucosal grafts and vascularized flaps, but post-op leak ... Full text Link to item Cite

Comparative outcomes of middle meningeal artery embolization with statins versus embolization alone in the treatment of chronic subdural hematoma: a systematic review and meta-analysis.

Journal Article Neurosurg Rev · October 3, 2023 Chronic subdural hematoma (cSDH) is common among the elderly, with surgical evacuation as a prevalent treatment, facing recurrence rates up to 30%. Recently, middle meningeal artery embolization (MMAE) has emerged as a promising approach, offering reduced ... Full text Link to item Cite

Use of Tympanostomy T-Tube for Endoscopic Endonasal Marsupialization of Small Rathke's Cleft Cysts: A Case Series.

Journal Article J Neurol Surg B Skull Base · August 2023 Objectives  This article describes a novel technique implementing the use of a tympanostomy t-tube to provide long-term marsupialization of small Rathke's cleft cysts (RCCs). Design  A retrospective review of electronic medical records was performed to col ... Full text Link to item Cite

A Nationwide Analysis of Aneurysmal Subarachnoid Hemorrhage Mortality, Complications, and Health Economics in the USA.

Journal Article Transl Stroke Res · June 2023 Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating neurological condition. Endovascular coiling or surgical clipping have equivocal success rates, but relatively little is known regarding the health economics and complications of these procedures a ... Full text Link to item Cite

Revisiting flow augmentation bypass for cerebrovascular atherosclerotic vaso-occlusive disease: Single-surgeon series and review of the literature.

Journal Article PLoS One · 2023 OBJECTIVE: Despite advances in the nonsurgical management of cerebrovascular atherosclerotic steno-occlusive disease, approximately 15-20% of patients remain at high risk for recurrent ischemia. The benefit of revascularization with flow augmentation bypas ... Full text Link to item Cite

Approaches to the Cerebellopontine Angle

Chapter · January 1, 2023 The cerebellopontine angle (CPA) is formed by the petrosal cerebellar surface, middle cerebellar peduncle, lateral pons, petrosal surface of the petrous bone, and clival portion of the occipital bone. While only accounting for 10–15% of intracranial tumors ... Full text Cite

Retrolabyrinthine transsigmoid approach to complex parabrainstem tumors in the posterior fossa.

Journal Article J Neurosurg · April 1, 2022 OBJECTIVE: The surgical management of large and complex tumors of the posterior fossa poses a formidable challenge in neurosurgery. The standard retrosigmoid craniotomy approach has been performed at most neurosurgical centers; however, the retrosigmoid ap ... Full text Link to item Cite

Long-Term Outcomes for Patients With Atypical or Malignant Meningiomas Treated With or Without Radiation Therapy: A 25-Year Retrospective Analysis of a Single-Institution Experience.

Journal Article Adv Radiat Oncol · 2022 PURPOSE: Atypical (World Health Organization [WHO] grade 2) and malignant (WHO grade 3) meningiomas have high rates of local recurrence, and questions remain about the role of adjuvant radiation therapy (RT) for patients with WHO grade 2 disease. These pat ... Full text Link to item Cite

Koos grade IV vestibular schwannomas: considerations on a consecutive series of 60 cases-searching for the balance between preservation of function and maximal tumor removal.

Journal Article Neurosurg Rev · December 2021 Koos grade IV vestibular schwannomas (VS) (maximum diameter > 3 cm) compress the brainstem and displace the fourth ventricle. Microsurgical resection with attention to the right balance between preservation of function and maximal tumor removal is the trea ... Full text Link to item Cite

Safety of the APOLLO Onyx delivery microcatheter for embolization of brain arteriovenous malformations: results from a prospective post-market study.

Journal Article J Neurointerv Surg · October 2021 BACKGROUND: Catheter retention and difficulty in retrieval have been observed during embolization of brain arteriovenous malformations (bAVMs) with the Onyx liquid embolic system (Onyx). The Apollo Onyx delivery microcatheter (Apollo) is a single lumen cat ... Full text Link to item Cite

Neurosurgical management of petrous bone lesions: classification system and selection of surgical approaches.

Journal Article Acta Neurochir (Wien) · October 2021 BACKGROUND: Surgery of petrous bone lesions (PBLs) is challenging for neurosurgeons. Selection of the surgical approach is an important key for success. In this study, the authors present an anatomical classification for PBLs that has been used by our grou ... Full text Link to item Cite

Petrous bone lesions: surgical implementation and outcomes of extradural subtemporal approach.

Journal Article Acta Neurochir (Wien) · October 2021 BACKGROUND: Petrous bone lesions (PBLs) are rare with few reports in the neurosurgical literature. In this study, the authors describe our current technique of extradural subtemporal approach (ESTA). The objective of this study was to evaluate the role and ... Full text Link to item Cite

How I do it: total resection of a giant sphenoclinoidal meningioma with normalization of near blind vision.

Journal Article Acta Neurochir (Wien) · September 2021 BACKGROUND: Resection of giant sphenoclinoidal meningiomas (SCLM) remains difficult. We discuss a patient presenting with right eye near blindness who underwent total removal of a giant SCLM, resulting in normal vision and no recurrence. METHOD: Utilizing ... Full text Link to item Cite

Management of unruptured incidentally found intracranial saccular aneurysms.

Journal Article Neurosurg Rev · August 2021 Unruptured intracranial saccular aneurysms occur in 3-5% of the general population. As the use of diagnostic medical imaging has steadily increased over the past few decades with the increased availability of computed tomography (CT) and magnetic resonance ... Full text Link to item Cite

Extradural anterior temporal fossa approach to the paranasal sinuses, nasal cavities through the anterolateral and anteromedial triangles: Combined microscopic and endoscopic strategy.

Journal Article Acta Neurochir (Wien) · August 2021 OBJECTIVE: To demonstrate the utility and limitations of the extradural endoscopic-assisted anterior temporal fossa approach to the pterygopalatine fossa (PPF), infratemporal fossa (ITF), paranasal sinuses (PS), parapharyngeal region (PPR), nasal cavities ... Full text Link to item Cite

Flow diversion of fusiform intracranial aneurysms.

Journal Article Neurosurg Rev · June 2021 Fusiform aneurysms are less common than saccular aneurysms, but have higher associated mortality and rebleeding rates. Recently, flow diversion has emerged as a possible treatment option. The purpose of this study was to determine the safety and efficacy o ... Full text Link to item Cite

Associations between Features of External Ventricular Drain Management, Disposition, and Shunt Dependence

Journal Article Journal of Neuroanaesthesiology and Critical Care · March 1, 2021 Background In the United States, nearly 25,000 patients annually undergo percutaneous ventriculostomy for the management of increased intracranial pressure with little consensus on extraventricular drain management. To characterize relationships between ex ... Full text Open Access Cite

Olfactory-Specific Quality of Life Outcomes after Endoscopic Endonasal Surgery of the Sella.

Journal Article Allergy & rhinology (Providence, R.I.) · January 2021 ObjectiveTo assess olfactory outcomes as measured by an olfactory-specific quality of life (QOL) questionnaire in patients undergoing EESBS for sellar lesions.DesignRetrospective case series.SettingTertiary academic medical cente ... Full text Cite

STA-enhanced vascularized galeal flap for revascularization of moyamoya disease: technical report.

Journal Article Acta Neurochir (Wien) · August 2020 BACKGROUND: A variety of revascularization techniques have been reported for the management of moyamoya disease to prevent risks of stroke. STA (superficial temporal artery)-MCA (middle cerebral artery) microanastomosis, single or double bypass, with tempo ... Full text Link to item Cite

Percutaneous Intervention for Left Ventricular Assist Device Outflow Obstruction.

Journal Article Heart Lung Circ · March 2020 Left ventricular assist devices (LVADs) are used to support patients with advanced systolic heart failure (HF). These patients might develop LVAD dysfunction and consequent HF symptoms. Occasionally, outflow graft obstruction is responsible for LVAD dysfun ... Full text Link to item Cite

Novel Application of Steroid Eluting Stent in Petrous Apex Cholesterol Granuloma.

Journal Article J Neurol Surg B Skull Base · October 2019 Objective  This study describes the safety and efficacy of mometasone furoate eluting stents in the management of petrous apex cholesterol granuloma approached through an endonasal endoscopic route and assesses the restenosis rate. Methods  Consecutive pat ... Full text Link to item Cite

Predictors of Clinical Outcome After Treatment of Intracranial Aneurysms with the Pipeline Embolization Device.

Journal Article World Neurosurg · October 2019 BACKGROUND: Flow-diverting stents have revolutionized the endovascular treatment of intracranial aneurysms. The purpose of this study is to identify predictors of adverse outcomes associated with the pipeline embolization device (PED). METHODS: A retrospec ... Full text Link to item Cite

Visualization of Dark Side of Skull Base with Surgical Navigation and Endoscopic Assistance: Extended Petrous Rhomboid and Rhomboid with Maxillary Nerve-Mandibular Nerve Vidian Corridor.

Journal Article World Neurosurg · September 2019 BACKGROUND: Lesions located at the petrous apex, cavernous sinus, clivus, medial aspect of the jugular foramen, or condylar regions are still difficult to fully expose using the operating microscope. Although approaches to this region through the middle cr ... Full text Link to item Cite

Sinonasal Quality of Life Outcomes After Extended Endonasal Approaches to the Skull Base.

Journal Article J Neurol Surg B Skull Base · August 2019 Introduction  Endoscopic endonasal skull base surgery (EESBS) leads to significant alterations in sinonasal anatomy and physiology. However, there is limited data available on quality of life (QOL) outcomes following EESBS. Methods  A retrospective review ... Full text Link to item Cite

Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure.

Journal Article Neurosurgery · June 1, 2019 BACKGROUND: Minimally invasive surgery procedures, including stereotactic catheter aspiration and clearance of intracerebral hemorrhage (ICH) with recombinant tissue plasminogen activator hold a promise to improve outcome of supratentorial brain hemorrhage ... Full text Link to item Cite

Translabyrinthine Approach

Chapter · January 25, 2019 The translabyrinthine approach gives access to the internal auditory canal (IAC) through mastoidectomy and drilling of semicircular canals and vestibule. Due to iatrogenic damage to the membranous labyrinth, postoperative hearing loss is expected so that t ... Full text Cite

Patient Positioning

Chapter · January 25, 2019 Lateral, supine, and semi-sitting positions are commonly used in vestibular schwannoma surgery. The lateral position, also known as Fukushima position, allows access to the cerebellopontine angle and combines satisfactory surgical exposure with anesthesiol ... Full text Cite

Hearing Preservation

Chapter · January 25, 2019 Hearing preservation in vestibular schwannoma surgery is most influenced by the selection of eligible patients: middle fossa or retrosigmoid approaches may be attempted in patients with small tumor size (<1.5–2 cm) and good preoperative hearing. As regards ... Full text Cite

Video Clips of the Surgical Steps

Chapter · January 25, 2019 Eight video clips are commented, showing the surgical steps of a standard retrosigmoid approach to a case of right-sided vestibular schwannoma, grade T4a according to Samii’s classification. Keyhole craniotomy is performed and followed by dural incision. F ... Full text Cite

Techniques of Dural Closure for Zero CSF Leak

Chapter · January 25, 2019 CSF fistulas into the soft tissues of the skull base can cause wound breakdown and/or pseudomeningocele, which often becomes very painful and debilitating. In addition, drainage of spinal fluid from the skin increases the risk for surgical site infections ... Full text Cite

Instrumentation for Acoustic Neuroma Microneurosurgery

Chapter · January 25, 2019 The most important instruments for vestibular schwannoma surgery can be grouped as follows: standard microsurgical instruments, electronic microsurgical devices, endoscopes, and intraoperative neurophysiological monitoring (IONM) devices. Standard—i.e., me ... Full text Cite

Usefulness of Laser and Ultrasound Aspirator

Chapter · January 25, 2019 The rationale for laser use in tumor resection is both to allow for “no-touch” cutting and for tissue debulking, with hemostatic benefit. Laser surgery, in general, has shown various advantages, such as reduction of mechanical trauma and intraoperative ble ... Full text Cite

Retrosigmoid Approach

Chapter · January 25, 2019 The retrosigmoid approach is most commonly performed in vestibular schwannoma surgery regardless of the tumor size, especially when hearing preservation is attempted; it is a safe option for small tumors, with low morbidity and good facial nerve and hearin ... Full text Cite

Face-to-Face Two-Surgeons Four-Hands Microsurgery

Chapter · January 25, 2019 Over the past 10 years, Fukushima established the gold standard of operatory room configuration as two-surgeons four-hands micro-neurosurgery, using face-to-face ocular arrangement of the modern floating operating microscope. Therefore, two surgeons observ ... Full text Cite

Intraoperative Identification 9 and Location of Facial Nerve: Type of Facial Nerve Displacement - How to Use Monopolar Stimulator

Chapter · January 25, 2019 Intraoperative facial nerve monitoring (IOFNM) is a neurophysiological method whose main purpose is to inform the surgical team of the actual neural function—and, indirectly, of the position—of the facial nerve (N VII) so that the operative strategy can be ... Full text Cite

Treatment of Dissecting Distal Vertebral Artery (V4) Aneurysms With Flow Diverters.

Journal Article Oper Neurosurg (Hagerstown) · July 1, 2018 BACKGROUND: Dissecting aneurysms of the intracranial vertebral arteries are rare; however, treatment of these presents multiple challenges, including high risk of rebleeding, development of thromboembolic strokes, and progressive partial thrombosis. Flow d ... Full text Link to item Cite

Two surgeons four-hand microneurosurgery with universal holder system: technical note.

Journal Article Neurosurg Rev · July 2017 A new technique for collaborative performance of complex skull base and cerebrovascular procedures is described. The benefits of this approach for patient safety and surgical education are discussed. ... Full text Link to item Cite

Carotid Endarterectomy to Remove Retained Solitaire Stent Retriever inside Carotid Stent after Mechanical Thrombectomy.

Journal Article J Stroke Cerebrovasc Dis · May 2017 BACKGROUND: Tandem occlusions of the internal carotid artery (ICA) and middle cerebral artery (MCA) occur in up to a third of patients with acute ischemic strokes undergoing endovascular mechanical thrombectomy. Understanding open neurosurgical management ... Full text Link to item Cite

Optimal pediatric dosing of anti-platelet agents for pipeline stent embolization -a case report and review of the literature.

Journal Article Childs Nerv Syst · April 2017 BACKGROUND: Various strategies are emerging for dosing antiplatelet therapies in preparation for pipeline stent embolization in adults. Hyper-response is associated with hemorrhagic complications. Hypo-response is associated with thromboembolic events. Dos ... Full text Link to item Cite

Rare Lesions of the Internal Auditory Canal.

Journal Article World Neurosurg · March 2017 BACKGROUND: Approximately 95% of tumors occurring within the internal auditory canal (IAC) are vestibular schwannomas. Many undergo stereotactic radiation without definitive tissue diagnosis. Rare IAC tumors are not all radiosensitive and are poorly descri ... Full text Link to item Cite

Endovascular management of spinal dural arteriovenous fistulas.

Journal Article Handb Clin Neurol · 2017 Spinal dural arteriovenous fistulas (dAVF) are the most common subset of the larger group of spinal vascular malformations. In this chapter, we discuss the definition, epidemiology, clinical presentation, diagnosis, treatment, and outcomes of spinal dAVF. ... Full text Link to item Cite

The Effect of Propofol vs. Isoflurane Anesthesia on Postoperative Changes in Cerebrospinal Fluid Cytokine Levels: Results from a Randomized Trial.

Journal Article Front Immunol · 2017 INTRODUCTION: Aside from direct effects on neurotransmission, inhaled and intravenous anesthetics have immunomodulatory properties. In vitro and mouse model studies suggest that propofol inhibits, while isoflurane increases, neuroinflammation. If these fin ... Full text Link to item Cite

Vascular lesions of the skull base

Chapter · January 1, 2017 Cerebrovascular diseases of the skull base represent a separate entity. Especially aneurysms located close to the skull base as well as dural arteriovenous fistulas require highly specialized neuroradiological diagnostics and an individualized treatment st ... Full text Cite

Isolated Deep Ear Canal Pain: Possible Role of Auricular Branch of Vagus Nerve-Case Illustrations with Cadaveric Correlation.

Journal Article World Neurosurg · December 2016 UNLABELLED: Glossopharyngeal, nervus intermedius, and vagus neuralgias can all present with ear pain. However, to our knowledge, there have been no reports of otalgia as the only symptom of vagus neuralgia. The seventh, ninth, and tenth cranial nerves have ... Full text Link to item Cite

Microsurgical resection of vestibular schwannomas: complication avoidance.

Journal Article J Neurooncol · November 2016 Vestibular schwannoma (VS) surgery requires appropriate patient selection, meticulous microsurgical technique and optimal post-operative care. Focused radiation is an effective alternative for the treatment of smaller VSs. For VS surgery to remain a reason ... Full text Link to item Cite

Simulation in Neurosurgery-A Brief Review and Commentary.

Journal Article World Neurosurg · May 2016 Neurosurgery is one of the most technically demanding and liable of all medical professionals. More than 75% of neurosurgical errors are deemed as preventable and technical in nature. Yet in a specialty that requires such high level of technical expertise, ... Full text Link to item Cite

The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer's Disease: Results of a Randomized Trial.

Journal Article J Alzheimers Dis · April 15, 2016 BACKGROUND: Preclinical studies have found differential effects of isoflurane and propofol on the Alzheimer's disease (AD)-associated markers tau, phosphorylated tau (p-tau) and amyloid-β (Aβ). OBJECTIVE: We asked whether isoflurane and propofol have diffe ... Full text Open Access Link to item Cite

Surgical management of vestibular schwannomas after failed radiation treatment.

Journal Article Neurosurg Rev · April 2016 Increasing numbers of patients with vestibular schwannoma (VS) have been treated with focused-beam stereotactic radiation treatment (SRT) including Gamma knife, CyberKnife, X-knife, Novalis, or proton beam therapy. The purpose of this study was to document ... Full text Link to item Cite

Middle infratemporal fossa less invasive approach for radical resection of parapharyngeal tumors: surgical microanatomy and clinical application.

Journal Article Neurosurg Rev · January 2016 Surgery of the infratemporal fossa (ITF) and parapharyngeal area presents a formidable challenge to the surgeon due to its anatomical complexity and limited access. Conventional surgical approaches to these regions were often too invasive and necessitate s ... Full text Link to item Cite

Preoperative Lumbar Drain Use During Acoustic Neuroma Surgery and Effect on CSF Leak Incidence.

Journal Article Ann Otol Rhinol Laryngol · January 2016 OBJECTIVE: To determine if preoperative lumbar drain (LD) use reduces the incidence of postoperative cerebrospinal fluid (CSF) leak in patients undergoing acoustic neuroma resection. METHODS: Retrospective review of 282 patients presenting for acoustic neu ... Full text Link to item Cite

Comprehensive Overview of Contemporary Management Strategies for Cerebral Aneurysms.

Journal Article World Neurosurg · October 2015 Aneurysmal subarachnoid hemorrhage (SAH) remains an important health issue in the United States. Despite recent improvements in the diagnosis and treatment of cerebral aneurysms, the mortality rate following aneurysm rupture. In those patients who survive, ... Full text Link to item Cite

Direct Repair of Iatrogenic Internal Carotid Artery Injury During Endoscopic Endonasal Approach Surgery With Temporary Endovascular Balloon-Assisted Occlusion: Technical Case Report.

Journal Article Neurosurgery · September 2015 BACKGROUND AND IMPORTANCE: Iatrogenic internal carotid artery (ICA) injuries during endoscopic endonasal approach (EEA) surgeries are associated with a high morbidity and mortality, with few acceptable methods described for repair. CLINICAL PRESENTATION: A ... Full text Link to item Cite

Rapid ventricular pacing for a basilar artery pseudoaneurysm in a pediatric patient: case report.

Journal Article J Neurosurg Pediatr · June 2015 Large cerebral aneurysms of the basilar apex are difficult to treat. Recently, endovascular treatment has mitigated much of the morbidity associated with treating these lesions. However, the morphology of aneurysms of the vertebrobasilar system can preclud ... Full text Link to item Cite

Adult surgical experience with Loeys-Dietz syndrome.

Journal Article Ann Thorac Surg · April 2015 BACKGROUND: Loeys-Dietz syndrome (LDS) results from mutations in receptors for the cytokine transforming growth factor-β leading to aggressive aortic pathology sometimes accompanied by specific phenotypic features including bifid uvula, hypertelorism, clef ... Full text Link to item Cite

Intra-operative hydroxyethyl starch is not associated with post-craniotomy hemorrhage.

Journal Article Springerplus · 2015 BACKGROUND: Intraoperative intravascular volume expansion with hydroxyethyl starch-based colloids is thought to be associated with an increased risk of post-craniotomy hemorrhage. Evidence for this association is limited. Associations between resuscitation ... Full text Open Access Link to item Cite

Enhanced, rapid occlusion of carotid and vertebral arteries using the AMPLATZER Vascular Plug II device: the Duke Cerebrovascular Center experience in 8 patients with 22 AMPLATZER Vascular Plug II devices.

Journal Article World Neurosurg · January 2015 OBJECTIVE: Therapeutic embolization of the common carotid artery (CCA), internal carotid artery (ICA), and vertebral artery (VA) is necessary in the treatment of a subset of chronic arteriovenous fistulas (AVFs), hemorrhages, highly vascularized neoplasms ... Full text Link to item Cite

Worse outcomes for patients undergoing brain tumor and cerebrovascular procedures following the ACGME resident duty-hour restrictions.

Journal Article J Neurosurg · August 2014 OBJECT: On July 1, 2003, the Accreditation Council for Graduate Medical Education (ACGME) implemented duty-hour restrictions for resident physicians due to concerns for patient and resident safety. Though duty-hour restrictions have increased resident qual ... Full text Link to item Cite

Transcirculation balloon-assisted stent-supported coil embolization of a basilar tip aneurysm.

Journal Article Neurosurg Focus · July 2014 We present the case of a balloon-assisted, stent-supported coil embolization of a basilar tip aneurysm. Initially, a balloon extending from the basilar artery into the right PCA was placed. However, even with a more proximal purchase, coils were found to i ... Full text Link to item Cite

Endovascular treatment of a spinal dural arteriovenous malformation (DAVF).

Journal Article Neurosurg Focus · July 2014 We present a case of a patient with rapid loss of motor strength in his lower extremities. He became bedridden with bowel and bladder incontinence, and developed saddle anesthesia. MRI of the lumbar spine showed edema in the conus medullaris and multiple f ... Full text Link to item Cite

Perioperative cardiac complications and 30-day mortality in patients undergoing intracranial aneurysmal surgery with adenosine-induced flow arrest: a retrospective comparative study.

Journal Article Neurosurgery · March 2014 BACKGROUND: Adenosine-induced flow arrest is a technique used to assist in the surgical clipping of complex aneurysms. OBJECTIVE: To assess the safety associated with adenosine-assisted intracranial aneurysm surgery. METHODS: Medical records of all patient ... Full text Link to item Cite

Predictors of extraventricular drain-associated bacterial ventriculitis.

Journal Article J Crit Care · February 2014 PURPOSE: Bacterial ventriculitis (BV) may develop in patients requiring external ventricular drains (EVDs). The purpose of this study was to determine predictors of EVD-associated BV onset. MATERIALS AND METHODS: A retrospective review of Duke University H ... Full text Link to item Cite

In reply.

Journal Article Neurosurgery · January 2014 Full text Link to item Cite

Effect of 6% hydroxyethyl starch 130/0.4 in 0.9% sodium chloride (Voluven®) on complications after subarachnoid hemorrhage: a retrospective analysis.

Journal Article Springerplus · December 2013 BACKGROUND: 6% Hydroxyethyl Starch 130/0.4 in 0.9% Sodium Chloride (Voluven®; 6% HES 130/0.4) is a colloid often used for fluid resuscitation in patients with subarachnoid hemorrhage (SAH), despite a lack of safety data for this use. The purpose of our stu ... Full text Open Access Link to item Cite

Less invasive transjugular approach with Fallopian bridge technique for facial nerve protection and hearing preservation in surgery of glomus jugulare tumors.

Journal Article Neurosurg Rev · October 2013 For the past three decades, surgery of glomus jugulare tumors (GJTs) has been characterized by extensive combined head and neck, neuro-otologic, and neurosurgical approaches. In recent years, the authors have modified the operative technique to a less inva ... Full text Link to item Cite

Continuous cerebral spinal fluid drainage associated with complications in patients admitted with subarachnoid hemorrhage.

Journal Article J Neurosurg · October 2013 OBJECT: Cerebral artery vasospasm is a major cause of death and disability in patients recovering from subarachnoid hemorrhage (SAH). Although the exact cause of vasospasm is unknown, one body of research suggests that clearing blood products by CSF draina ... Full text Link to item Cite

The Use of Adenosine in Cerebral Aneurysm Clipping: A Review

Journal Article Current Anesthesiology Reports · September 1, 2013 Management of intracranial aneurysms continues to evolve, with coiling of aneurysms becoming an increasingly used modality. However, for aneurysms which are considered to be “complex” due to their size, position, or morphology, clipping continues to be the ... Full text Cite

Contemporary surgical management of vestibular schwannomas: analysis of complications and lessons learned over the past decade.

Journal Article Neurosurgery · June 2013 BACKGROUND: Despite advanced microsurgical techniques, more refined instrumentation, and expert team management, there is still a significant incidence of complications in vestibular schwannoma surgery. OBJECTIVE: To analyze complications from the microsur ... Full text Link to item Cite

Long-term economic impact of coiling vs clipping for unruptured intracranial aneurysms.

Journal Article Neurosurgery · June 2013 BACKGROUND: : Treatment of unruptured intracranial aneurysms (UIAs) involves endovascular coiling or aneurysm clipping. While many studies have compared these treatment modalities with respect to various clinical outcomes, few studies have investigated the ... Full text Link to item Cite

Transient complete lower facial nerve palsy after craniotomy for aneurysm clipping.

Journal Article Br J Neurosurg · April 2013 We present the case of a 41-year old female who developed a complete facial nerve palsy after an interhemispheric approach for clipping of a distal anterior cerebral artery aneurysm. Work-up revealed that she had developed acute parotitis during surgery, p ... Full text Link to item Cite

Subarachnoid hemorrhage trials.

Journal Article J Neurosurg · January 2013 Full text Link to item Cite

Improved delivery of the Neuroform 3 stent: technical note.

Journal Article J Neurointerv Surg · July 2012 BACKGROUND: Intracranial stents have expanded endovascular therapy to wide neck aneurysms whose dimensions and configurations are not amendable to coil embolization alone. Stents however have not eliminated all problems due to technical factors with their ... Full text Link to item Cite

Visual complications after stent-assisted endovascular embolization of paraophthalmic and suprasellar variant superior hypophyseal aneurysms: the Duke Cerebrovascular Center experience in 57 patients.

Journal Article World Neurosurg · 2012 OBJECTIVE: To review retrospectively experience with stent-assisted coiling of ophthalmic segment internal carotid artery (ICA) aneurysms to report outcome data and identify the rate of associated visual complications. METHODS: The Duke endovascular databa ... Full text Link to item Cite

Stent-assisted coil emboilization of ruptured intracranial aneurysms: A retrospective multicenter review.

Journal Article Surg Neurol Int · 2012 BACKGROUND: The purpose of this study is to retrospectively review our experience with stent-assisted embolization of patients with an acutely ruptured cerebral aneurysm. METHODS: Medical records and imaging were reviewed for 36 patients who underwent sten ... Full text Link to item Cite

Clipping of a cerebral aneurysm in a patient with Loeys-Dietz syndrome: case report.

Journal Article Neurosurgery · September 2011 BACKGROUND AND IMPORTANCE: his is the first case report of clipping a cerebral aneurysm in a patient with Loeys-Dietz syndrome (LDS). LDS is a newly described autosomal dominant connective tissue disease with systemic vascular involvement. Unique to this s ... Full text Link to item Cite

Thromboembolic complications after Neuroform stent-assisted treatment of cerebral aneurysms: the Duke Cerebrovascular Center experience in 235 patients with 274 stents.

Journal Article Neurosurgery · August 2011 BACKGROUND: The Neuroform Stent has facilitated the endovascular treatment of wide-necked cerebral aneurysms. It is unknown which factors pose risks of thromboembolic events after stent placement. OBJECTIVE: This series is the largest single-center study r ... Full text Link to item Cite

Surgical capacity building in Uganda through twinning, technology, and training camps.

Journal Article World J Surg · June 2011 BACKGROUND: Neurosurgical capacity is extremely deficient in East African countries where 27 neurosurgeons serve more than 250 million people. To build capacity, the Duke University Medical Center and New Mulago Hospital in Uganda applied a two-pronged twi ... Full text Link to item Cite

Endovascular treatment of venous sinus thrombosis: a case report and review of the literature.

Journal Article J Neurointerv Surg · March 2011 Dural venous sinus thrombosis (DVST) is a pathological phenomenon resulting from vascular occlusion of the cerebral venous sinuses. The mainstay of therapy for DVST is anticoagulation but more aggressive interventional therapies must be considered when med ... Full text Link to item Cite

Embolization of an unruptured distal lenticulostriate aneurysm associated with moyamoya disease.

Journal Article AJNR. American journal of neuroradiology · March 2011 Lenticulostriate aneurysms are rare and usually present with intracranial hemorrhage, limiting understanding of their natural course. We describe an unusual case of an unruptured rapidly growing distal LSA aneurysm in the setting of Moyamoya disease, succe ... Full text Cite

Continuous and intermittent CSF diversion after subarachnoid hemorrhage: a pilot study.

Journal Article Neurocrit Care · February 2011 BACKGROUND: We examine two accepted methods of managing cerebrospinal fluid (CSF) drainage in patients following subarachnoid hemorrhage (SAH). The first is intermittent CSF drainage when intracranial pressure (ICP) reaches a pre-defined threshold (monitor ... Full text Link to item Cite

Endovascular management of inadvertent brachiocephalic arterial catheterization.

Journal Article J Neurosurg · January 2011 OBJECT: Inadvertent catheterization of brachiocephalic arteries (carotid artery, subclavian artery, or vertebral artery) during attempted placement of a central venous catheter can have potentially disastrous complications. While removal of the catheter in ... Full text Link to item Cite

An observational pilot study of CSF diversion in subarachnoid haemorrhage.

Journal Article Nurs Crit Care · 2011 BACKGROUND: A primary focus of hospital treatment following admission for subarachnoid haemorrhage (SAH) is a prevention of cerebral artery vasospasm, which may result in ischaemic stroke. Intraventricular catheter (IVC) insertion to facilitate cerebral sp ... Full text Link to item Cite

Adenosine-induced transient asystole for intracranial aneurysm surgery: a retrospective review.

Journal Article J Neurosurg Anesthesiol · January 2011 UNLABELLED: BRIEF SUMMARY: We describe the use of adenosine-induced cardiac arrest to facilitate intracranial aneurysm clip ligation. BACKGROUND: Cerebral aneurysms are highly variable which may result in difficult surgical exposure for clip ligation in se ... Full text Link to item Cite

Transient adenosine-induced asystole during the surgical treatment of anterior circulation cerebral aneurysms: technical note.

Journal Article Neurosurgery · December 2010 BACKGROUND: Transient adenosine-induced asystole is a reliable method for producing a short period of relative hypotension during surgical and endovascular procedures. Although the technique has been described in the endovascular treatment of brain arterio ... Full text Link to item Cite

Combined microsurgical and endovascular treatment of a giant left middle cerebral artery aneurysm.

Journal Article J Neurointerv Surg · September 2010 Giant fusiform aneurysms of the middle cerebral artery (MCA) bifurcation pose significant treatment challenges. A giant fusiform aneurysm of the left MCA in a pediatric patient, which persisted despite Hunterian ligation of the M1 and double barrel superfi ... Full text Link to item Cite

Stereotactic radiosurgery in the treatment of a dural carotid-cavernous fistula.

Journal Article J Neuroophthalmol · June 2010 Because of the success of stereotactic radiosurgery (SRS) in the treatment of cerebral arteriovenous malformations (AVMs), SRS is being applied to the treatment of carotid-cavernous dural arteriovenous fistulas (CCDAVFs) when these lesions are not accessib ... Full text Link to item Cite

Anatomic variant of the posterior cerebral artery.

Journal Article AJR Am J Roentgenol · April 2007 Full text Link to item Cite

An eclectic history of peripheral nerve surgery.

Journal Article Neurosurg Clin N Am · April 2004 It is hard to decide where history stops and contemporary development of peripheral nerve surgery begins. This article provides an eclectic view of the history of peripheral nerve surgery. In trying to keep the story moving, the publications of many author ... Full text Link to item Cite

Sacral tuberculosis: a case report and review of the literature.

Journal Article Surg Neurol · February 2004 BACKGROUND: We present a patient with a heterogeneously enhancing lesion within the body of the sacrum and the sacral canal. Sacral tuberculosis (TB) was suspected because of a history of familial exposure. Few cases isolated to the sacrum have been report ... Full text Link to item Cite

The value of magnetic resonance imaging in the evaluation of fatty filum terminale.

Journal Article Neurosurgery · February 2004 OBJECTIVE: To determine whether there are magnetic resonance imaging (MRI) characteristics of fatty fila that are correlated with neurological deficits, especially in the presence of a normal-level conus medullaris. METHODS: Lumbosacral MRI scans were revi ... Full text Link to item Cite

Advances in treatment of spinal cord and peripheral nerve injury

Chapter · January 1, 2004 An estimated 400,000 people in the U.S. have permanent paralysis as a consequence of spinal cord injury and an additional 10,000 are injured each year. Patients with spinal cord injuries (SCI) can live 25 to 30 years after their initial injuries. Each pati ... Cite

Clinical outcome differences for lipomyelomeningoceles, intraspinal lipomas, and lipomas of the filum terminale.

Journal Article Neurosurg Rev · December 2001 Failure to differentiate between the different types of lumbosacral lipomas may lead to inaccurate assumptions and inappropriate management of patients. The goal of this study was to determine whether there is a difference in clinical outcome between patie ... Full text Link to item Cite

Netrin-1 and peripheral nerve regeneration in the adult rat.

Journal Article Exp Neurol · February 2000 Axonal guidance during development of the nervous system is thought to be highly regulated through interactions of axons with attractive, repulsive, and trophic cues. Similar mechanisms regulate axonal regeneration after injury. The netrins have been shown ... Full text Link to item Cite