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Continuous and intermittent CSF diversion after subarachnoid hemorrhage: a pilot study.

Publication ,  Journal Article
Kim, GS; Amato, A; James, ML; Britz, GW; Zomorodi, A; Graffagnino, C; Zomorodi, M; Olson, DM
Published in: Neurocrit Care
February 2011

BACKGROUND: We examine two accepted methods of managing cerebrospinal fluid (CSF) drainage in patients following subarachnoid hemorrhage (SAH). The first is intermittent CSF drainage when intracranial pressure (ICP) reaches a pre-defined threshold (monitor-first) and the second is continuous CSF drainage (drain-first) at set pressure thresholds. This pilot study is designed to determine if there is a cause for a randomized study of comparing the two methods. METHODS: This prospective observational pilot study enrolled 37 patients with SAH and external ventricular drainage between October 2008 and August 2009. Patients were treated with one of two methods of ICP management (drain-first vs. monitor-first) according to the discretion of the admitting physician. RESULTS: There were no significant differences in baseline characteristics including age, gender, severity of neurological dysfunction, and radiographic findings between the two groups. The incidence of vasospasm was not different between the drain-first group (66.7%; 16 of 24 patients) and the monitor-first group (53.9%; 7 of 13 patients). CONCLUSION: This pilot study was neither powered, nor expected to detect a difference between groups. The results of this study provide support for the design and conduct of a randomized study to assess the impact of two methods of CSF diversion for patients with SAH.

Duke Scholars

Published In

Neurocrit Care

DOI

EISSN

1556-0961

Publication Date

February 2011

Volume

14

Issue

1

Start / End Page

68 / 72

Location

United States

Related Subject Headings

  • Vasospasm, Intracranial
  • Subarachnoid Hemorrhage
  • Prospective Studies
  • Pilot Projects
  • Neurology & Neurosurgery
  • Monitoring, Physiologic
  • Middle Aged
  • Male
  • Intracranial Hypertension
  • Incidence
 

Citation

APA
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ICMJE
MLA
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Kim, G. S., Amato, A., James, M. L., Britz, G. W., Zomorodi, A., Graffagnino, C., … Olson, D. M. (2011). Continuous and intermittent CSF diversion after subarachnoid hemorrhage: a pilot study. Neurocrit Care, 14(1), 68–72. https://doi.org/10.1007/s12028-010-9401-y
Kim, G. S., A. Amato, M. L. James, G. W. Britz, A. Zomorodi, C. Graffagnino, M. Zomorodi, and DaiWai M. Olson. “Continuous and intermittent CSF diversion after subarachnoid hemorrhage: a pilot study.Neurocrit Care 14, no. 1 (February 2011): 68–72. https://doi.org/10.1007/s12028-010-9401-y.
Kim GS, Amato A, James ML, Britz GW, Zomorodi A, Graffagnino C, et al. Continuous and intermittent CSF diversion after subarachnoid hemorrhage: a pilot study. Neurocrit Care. 2011 Feb;14(1):68–72.
Kim, G. S., et al. “Continuous and intermittent CSF diversion after subarachnoid hemorrhage: a pilot study.Neurocrit Care, vol. 14, no. 1, Feb. 2011, pp. 68–72. Pubmed, doi:10.1007/s12028-010-9401-y.
Kim GS, Amato A, James ML, Britz GW, Zomorodi A, Graffagnino C, Zomorodi M, Olson DM. Continuous and intermittent CSF diversion after subarachnoid hemorrhage: a pilot study. Neurocrit Care. 2011 Feb;14(1):68–72.
Journal cover image

Published In

Neurocrit Care

DOI

EISSN

1556-0961

Publication Date

February 2011

Volume

14

Issue

1

Start / End Page

68 / 72

Location

United States

Related Subject Headings

  • Vasospasm, Intracranial
  • Subarachnoid Hemorrhage
  • Prospective Studies
  • Pilot Projects
  • Neurology & Neurosurgery
  • Monitoring, Physiologic
  • Middle Aged
  • Male
  • Intracranial Hypertension
  • Incidence