Andrew Darrell Krystal

Professor Emeritus of Psychiatry and Behavioral Sciences

Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences

andrew.krystal@duke.edu

Box 3309 Med Ctr, Durham, NC 27710

54221 Hosp South, Durham, NC 27710

More About This Person

At a Glance

Credentials
1. Education

Academic Experience
1. Current Appointments & Affiliations
2. Previous Appointments & Affiliations

Expertise

Research
1. Selected Grants

Publications
1. Selected Publications

Artistic Works / Events

Teaching

Advising & Mentoring

Recognition
1. Awards & Honors
2. In the News

Professional Activities

Selected Grants

Obstructive Sleep Apnea Screening in Pregnant Women with Chronic Hypertension

ResearchSignificant Contributor · Awarded by Society for Obstetric Anesthesia and Perinatology · 2017 - 2020

KOR Phase 2A Study - Mod 3 (Advanced Understanding)

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2017

Modified KOR Phase 2A Study

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2017

Study to Evaulate the Kappa Opioid Receptor as a Target for the Treatment of Mood and Anxiety Spectrum Disorders by Evaluating Whether LY2456302 Engages Reward-related Neural Circuitry.

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2013 - 2017

Janssen OBSERVEMDD0001

Clinical TrialPrincipal Investigator · Awarded by Janssen Research & Development, LLC · 2015 - 2017

2/3 Reducing Suicide Ideation Through Insomnia Treatment (REST-IT)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2017

Multicenter Study of the Safety and Efficacy of JZP-110

Clinical TrialPrincipal Investigator · Awarded by Jazz Pharmaceuticals · 2015 - 2017

Transcranial Direct Current Stimulation (tDCS) as a Treatment for Acute Fear

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2017

The Duke Multidisciplinary Training Program in Pediatric Lung Disease

Inst. Training Prgm or CMEFaculty Member · Awarded by National Institutes of Health · 2010 - 2016

An Open-Label and Double-Blind Study to Investigate Evoked Potentials as Markers of Ketamine-Induced Cortical Plasticity

Clinical TrialPrincipal Investigator · Awarded by Janssen Research & Development, LLC · 2013 - 2015

FAST- MAS Administrative Task Year 3

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2015

Fast-Fail Trials in Mood and Anxiety Spectrum Disorders (FAST-MAS)

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2015

An Exploratory Phase II Study to Determine the Safety, Tolerability, and Activity of a Novel Vasopressin 1a Receptor Antagonist (SRX246) in Adults with DSM-5 Intermittent Explosive Disorder (IED)

Clinical TrialPrincipal Investigator · Awarded by Azevan Pharmaceuticals, Inc. · 2014 - 2015

A Phase I Study of the Kappa Opiate Receptor Occupancy and Clinical Mu Opiate Receptor Effects Associated with Repeated Dosing of LY2456302 Trial

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2013 - 2015

Effect of SEP-363856 in Narcolepsy

Clinical TrialPrincipal Investigator · Awarded by Sunovion Pharmaceuticals, Inc · 2015 - 2015

A Multicenter, Double-blind, Randomized, Parallel-group, Pilot Study to Assess the Short-term Safety and Tolerability of Lorcaserin Plus Two Doses of Immediate-Release Phentermine-HCl Compared With Lorcaserin Alone in Overweight and Obese Adults

Clinical TrialPrincipal Investigator · Awarded by Eisai, Inc. · 2013 - 2014

FAST- MAS Administrative Task Year 2

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2013 - 2014

Nocturnal Deterusor Overactivity In Overactive Bladder Syndrome

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2010 - 2014

Sleep EEG and Genetic Biomarkers of the Response to CBT for Insomnia in Major Depression

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2009 - 2014

3/3: Improving Depression Outcome by Adding CBT for Insomnia to Antidepressants

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2008 - 2014

Behavioral Insomnia Therapy for those with Insomnia and Depression

ResearchCo Investigator · Awarded by National Institutes of Health · 2008 - 2012

1/2 Sequenced therapies for comorbid and primary insomnias

ResearchCo Investigator · Awarded by National Institutes of Health · 2011 - 2012

Behavioral Insomnia Therapy with Fibromyalgia

ResearchPhysician · Awarded by National Institutes of Health · 2005 - 2012

Behavioral Insomnia Treatment in Chronic Fatigue Syndrome

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2007 - 2009

Classifying Psychiatric, Medical, and Primary Insomnias

ResearchClinical Investigator · Awarded by National Institutes of Health · 2003 - 2009

Combined Behavioral/Pharmacological Therapy for Insomnia

ResearchCo Investigator · Awarded by National Institutes of Health · 2001 - 2007

Sleep EEG Spectral Measures of Insomnia

ResearchCo Investigator · Awarded by National Institutes of Health · 2003 - 2006

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ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1998 - 2004

Behavioral Insomnia Therapy for Fibromyalgia Patients

ResearchCo Investigator · Awarded by National Institutes of Health · 1999 - 2003

Improving Ect Effectiveness Through Total Eeg Analysis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1994 - 1999

Improving Effectiveness Through Ictal Eeg Anaysis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1994 - 1999

Improving Ect Effectivness Through Ictal Eeg Analysis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1994 - 1999