Brian H. Eichner

Journal Article J Autism Dev Disord · July 12, 2024 PURPOSE: Early detection and intervention are associated with improved outcomes for autistic children. Thus, it is important to understand factors influencing early screening tools designed to detect autism. This study examined the relationship between car ... Full text Link to item Cite

Large-scale Validation of a Scalable and Portable Behavioral Digital Screening Tool for Autism at Home

Conference Conference on Human Factors in Computing Systems - Proceedings · May 11, 2024 Autism, characterized by challenges in socialization and communication, benefits from early detection for prompt and timely intervention. Traditional autism screening questionnaires often exhibit reduced accuracy in primary care settings and significantly ... Full text Cite

Early detection of autism using digital behavioral phenotyping.

Journal Article Nat Med · October 2023 Early detection of autism, a neurodevelopmental condition associated with challenges in social communication, ensures timely access to intervention. Autism screening questionnaires have been shown to have lower accuracy when used in real-world settings, su ... Full text Link to item Cite

Enhancing early autism prediction based on electronic records using clinical narratives.

Journal Article J Biomed Inform · August 2023 Recent work has shown that predictive models can be applied to structured electronic health record (EHR) data to stratify autism likelihood from an early age (<1 year). Integrating clinical narratives (or notes) with structured data has been shown to impro ... Full text Link to item Cite

Relationship between quantitative digital behavioral features and clinical profiles in young autistic children.

Journal Article Autism Res · July 2023 Early behavioral markers for autism include differences in social attention and orienting in response to one's name when called, and differences in body movements and motor abilities. More efficient, scalable, objective, and reliable measures of these beha ... Full text Link to item Cite

Firearm Safety Counseling in Pediatric Primary Care.

Journal Article N C Med J · July 2023 Injury from firearms is the leading cause of death among children and adolescents in the United States. Prevention requires a multi-pronged approach involving clinicians and policy. One evidence-based method to improve firearm safety is counseling with loc ... Full text Link to item Cite

Blink rate and facial orientation reveal distinctive patterns of attentional engagement in autistic toddlers: a digital phenotyping approach.

Journal Article Sci Rep · May 3, 2023 Differences in social attention are well-documented in autistic individuals, representing one of the earliest signs of autism. Spontaneous blink rate has been used to index attentional engagement, with lower blink rates reflecting increased engagement. We ... Full text Link to item Cite

Predictive Value of Early Autism Detection Models Based on Electronic Health Record Data Collected Before Age 1 Year.

Journal Article JAMA Netw Open · February 1, 2023 IMPORTANCE: Autism detection early in childhood is critical to ensure that autistic children and their families have access to early behavioral support. Early correlates of autism documented in electronic health records (EHRs) during routine care could all ... Full text Link to item Cite

Child Physical Health: Introduction

Chapter · January 31, 2023 The second volume continues with psychological and behavioral developments which contain topics on emotion, mindfulness, stress, depression, coping skills, cognitive developments, decision-making and trauma. ... Cite

Child Physical Health

Child physical health introduction

Chapter · January 1, 2023 Child physical health depends on a multitude of factors- genetics, environment, and access to adequate resources including access to education, preventative health care, and, for some children, subspecialty care. Infant and early childhood development, gro ... Full text Cite

Infants' diminished response to DTaP vaccine is associated with exposure to organophosphate esters.

Journal Article Sci Total Environ · September 1, 2022 Organophosphate esters (OPEs) are commonly applied as flame retardants and plasticizers. Toxicological studies suggest exposure effects on immune endpoints, raising concerns as infants' OPE exposures are elevated compared to older children and adults due t ... Full text Link to item Cite

A scalable computational approach to assessing response to name in toddlers with autism.

Journal Article J Child Psychol Psychiatry · September 2021 BACKGROUND: This study is part of a larger research program focused on developing objective, scalable tools for digital behavioral phenotyping. We evaluated whether a digital app delivered on a smartphone or tablet using computer vision analysis (CVA) can ... Full text Link to item Cite

Computational Methods to Measure Patterns of Gaze in Toddlers With Autism Spectrum Disorder.

Journal Article JAMA Pediatr · August 1, 2021 IMPORTANCE: Atypical eye gaze is an early-emerging symptom of autism spectrum disorder (ASD) and holds promise for autism screening. Current eye-tracking methods are expensive and require special equipment and calibration. There is a need for scalable, fea ... Full text Link to item Cite

Reconsidering an Appropriate Urinary Biomarker for Flame Retardant Tris(1-chloro-2-propyl) Phosphate (TCIPP) Exposure in Children

Journal Article Environmental Science and Technology Letters · January 12, 2021 Tris(1-chloro-2-propyl) phosphate (TCIPP) is frequently applied to consumer products as a flame retardant and is commonly detected in indoor environments. Urinary bis(1-chloro-2-propyl) phosphate (BCIPP) is typically measured as TCIPP's primary biomarker b ... Full text Cite

Young infants' exposure to organophosphate esters: Breast milk as a potential source of exposure.

Journal Article Environ Int · October 2020 Organophosphate esters (OPEs) are applied as both flame retardants and plasticizers to a variety of consumer items such as home furnishings, construction materials, and children's products. While some assessments have characterized exposure among toddlers ... Full text Link to item Cite

A Community-based Assessment of Skin Care, Allergies, and Eczema (CASCADE): an atopic dermatitis primary prevention study using emollients-protocol for a randomized controlled trial.

Journal Article Trials · March 4, 2020 BACKGROUND: Atopic dermatitis (AD) is a common, chronic skin disorder often beginning in infancy. Skin barrier dysfunction early in life serves as a central event in the pathogenesis of AD. In infants at high risk of developing AD, preventative application ... Full text Link to item Cite

Lower Urinary Tract Symptoms in Older Children With and Without Diabetes Mellitus.

Journal Article Clin Pediatr (Phila) · November 2018 Lower urinary tract symptoms (LUTS) are an underrecognized complication of diabetes mellitus (DM) in adults and have undergone limited investigation in children. We estimated the prevalence of LUTS in 120 older children (11-17 years) with and without DM an ... Full text Link to item Cite

Open-Label Pilot Study to Compare the Safety and Immunogenicity of Pentavalent Rotavirus Vaccine (RV5) Administered on an Early Alternative Dosing Schedule with Those of RV5 Administered on the Recommended Standard Schedule.

Journal Article J Pediatric Infect Dis Soc · February 19, 2018 This study compares the safety and immunogenicity of pentavalent rotavirus vaccine (RV5) administered on an alternative schedule (initiated at 2-5 weeks of age) with those of RV5 administered on the recommended standard schedule. Our findings support the f ... Full text Link to item Cite

Teaching Physicians Motivational Interviewing for Discussing Weight With Overweight Adolescents.

Journal Article J Adolesc Health · July 2016 PURPOSE: We tested whether an online intervention combined with a patient feedback report improved physicians' use of motivational interviewing (MI) techniques when discussing weight with overweight and obese adolescents. METHODS: We randomized 46 pediatri ... Full text Link to item Cite

Safety and Immunogenicity of Sequential Rotavirus Vaccine Schedules.

Journal Article Pediatrics · February 2016 BACKGROUND AND OBJECTIVES: Although both licensed rotavirus vaccines are safe and effective, it is often not possible to complete the schedule by using the same vaccine formulation. The goal of this study was to investigate the noninferiority of the immune ... Full text Link to item Cite

High-Value Care Pediatric Curriculum

Journal Article MedEdPORTAL · July 16, 2015 Full text Cite

Persistent antibody depletion after rituximab in three children with autoimmune cytopenias.

Journal Article Pediatr Hematol Oncol · November 2009 Featured Publication We report 3 children who developed persistent antibody depletion and abnormal response to bacteriophage after rituximab treatment for autoimmune cytopenias. Whether these patients have developed immunodeficiency secondary to an underlying disease process, ... Full text Link to item Cite