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Laura Elizabeth Case

Associate Professor in Orthopaedic Surgery
Orthopaedic Surgery, Physical Therapy
DUMC 104002, 2200 West Main Street, Suite A210, Erwin, Durham, NC 27708
Doctor of Physical Therapy Division, DUMC Box 104002, Durham, NC 27710

Selected Grants


Understanding cognitive and neurological pathologies in infantile Pompe disease CNS

Clinical TrialPhysical Therapist · Awarded by Genzyme Corporation · 2022 - 2024

Understanding cognitive and neurological pathologies in infantile Pompe disease CNS

Clinical TrialPhysical Therapist · Awarded by Genzyme Corporation · 2019 - 2021

Electrical Impedance Myography and Muscle Ultrasound: Longitudinal Measures in Pompe Disease

Clinical TrialInvestigator · Awarded by Genzyme Corporation · 2016 - 2021

GSD III Clinical Data Manuscript Preparation

ResearchInvestigator · Awarded by Ultragenyx Pharmaceutical · 2019 - 2021

Understanding cognitive and neurological pathologies in infantile Pompe disease CNS

Clinical TrialPhysical Therapist · Awarded by Genzyme Corporation · 2022 - 2024

Understanding cognitive and neurological pathologies in infantile Pompe disease CNS

Clinical TrialPhysical Therapist · Awarded by Genzyme Corporation · 2019 - 2021

Electrical Impedance Myography and Muscle Ultrasound: Longitudinal Measures in Pompe Disease

Clinical TrialInvestigator · Awarded by Genzyme Corporation · 2016 - 2021

GSD III Clinical Data Manuscript Preparation

ResearchInvestigator · Awarded by Ultragenyx Pharmaceutical · 2019 - 2021

A Phase I Study of the Safety of AAV2/8 LSPhGAA in Late-onset Pompe Disease

Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2017 - 2020

Respiratory Muscle Training in Individuals With Pompe Disease

ResearchInvestigator · Awarded by National Institutes of Health · 2016 - 2019

Understanding cognitive and neurological pathologies in infantile Pompe disease

Clinical TrialPhysical Therapist · Awarded by Genzyme Corporation · 2016 - 2018

Supplemental Funding for Phase 1/2 study of Clenbuterol for the Treatment of Pompe Disease

Clinical TrialCo Investigator · Awarded by Roivant Sciences, Inc. · 2015 - 2016

Phase 1/2 Study of Clenbuterol for the Treatment of Pompe Disease

Clinical TrialCo Investigator · Awarded by Food and Drug Administration · 2013 - 2016

Clinical Trial Planning in Pompe Disease

ResearchCo Investigator · Awarded by National Institutes of Health · 2013 - 2014

External Relationships


  • Amicus Therapeutics
  • AskBio (Actus)
  • Avexis, Inc
  • Biogen Idec Inc.
  • CINRG (Cooperative International Neuromuscular Research Group)
  • Amicus Therapeutics
  • AskBio (Actus)
  • Avexis, Inc
  • Biogen Idec Inc.
  • CINRG (Cooperative International Neuromuscular Research Group)
  • CryoCell International
  • Genzyme Corporation (Sanofi Aventis)
  • IONIS Pharmaceuticals
  • Marcus Foundation
  • NS Pharma - (parent company is Nippon Shinyaku)
  • PTC Therapeutics
  • Pfizer Inc.
  • ReveraGen
  • Robertson Foundation
  • Sarepta Therapeutics

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.