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Ching-yi Chang

Associate Research Professor of Pharmacology and Cancer Biology
Pharmacology & Cancer Biology
Box 103057, Durham, NC 27710
Medical Science Res Bldg III, 3 Genome Court, Durham, NC 27710

Advising & Mentoring


Past graduate students:

Andrea Sherk (2001-2007)

Thesis project: Elucidation of the molecular mechanisms underlying androgen-mediated regulation of prostate cancer growth and progression

Tianyu Li (2001-2007)

Thesis Project: Molecular mechanisms underlying the estrogen regulated lipid homeostasis in the liver

Niharika Bansal Mettu (1001-2007)

Thesis Project: Targeting the coactivator interaction surface as a mechanism of regulating nuclear receptor transcriptional activity

Rebecca Stein (2004-2008)

Thesis Project: Defining the functional significance of estrogen-related receptor alpha in breast cancer

Hilary Wade (2005-2009)

Thesis Project: Multimodal regulation of gene transcription by progestins

Junfei Liu (2009-2013)

Thesis Project: Molecular dissection and functional definition of estrogen-related receptor alpha

Abby Brunner (2009-2015)

Thesis Project: Targeting Histone Deacetylase in Advanced Prostate Cancer

Kim Cocce (2014-2017)

Thesis Project: Molecular mechanisms governing the untoward tumor growth promoting effects of Selective Estrogen Receptor Modulators

Kaitlyn Andreano (2015-2020):

Thesis Project: Definition of the mechanisms involved in the anti-inflammatory actions of steroid hormones

Taylor Krebs (2016-2021)

Thesis project: Identification of endocrine therapy induced targetable vulnerabilities in cancer

Felicia Lim (2017-2023)

Thesis project: The roles of estrogens in immune functions and breast cancer pathogenesis 

Patrick Juras (2016-2023)

Thesis project: The role of CaMKK2 in natural killer cell anti-tumor immunity

Jovita Byemerwa (2018-2023)

Thesis project: Elucidation of the Role(s) of Estrogens in Regulating Natural Killer Cell Biology in Breast Cancer Metastasis

 

Past postdoctoral fellows:

Dmitri Kazmin (2002-2007): (1) Linking ligand-induced alterations in androgen receptor structure to gene expression and (2) Define the clinical significance of estrogen-related receptor alpha using gene expression signature.

Sakiko Kobayashi (2006-2010): Define the mechanisms involved in the anti-inflammatory actions of progestins in breast cancer

Mary Dwyer (2005-2011): Define WNT11 as a direct target of ERRα and beta-catenin pathway and its involvement in breast cancer migration

Scott Lawrence (2011-2015): Identification of the structural determinants of ERRα degrader

James Stice (2009-2016): RIP140 as a mediator of the anti-inflammatory actions of progestins in breast cancer

Mahmoud Alfaqih (2010-2013): Regulation of cholesterol homeostasis by CYP27A1 and its metabolite, 27-hydroxycholesterol, in Prostate Cancer

Sunghee Park (2011-2017): ERRα-regulated mitochondria metabolism in breast cancer pathogenesis

Wen Liu (2014-2020): CYP27A1 and 27-hydroxycholesterol in immune modulation and breast cancer progression

Debarati Mukherjee (2016-2022): The cancer cell intrinsic and extrinsic actions of CaMKK2

Binita Chakraborty (2015-2021): The effects of estrogen and estrogen-receptor modulators in immune function and breast cancer progression

Corine Haines (2019-2022): Regulation of cancer associated fibroblasts by estrogens

Sandeep Artham (2018-2024): The impact of estrogen signaling in tumor-associated tissue eosinophilia and breast cancer pathogenesis

 

Current graduate students:

Min-Yu Ko (2021-present): Elucidating the mechanisms by which androgens induce mTOR activation

Caleb McIver (2023-present): The impact of estrogens on dendritic cells function and hematopoiesis

Christopher Shields (2023-present): The CaMKK2/PDE1 signaling axis in breast cancer metastasis

Jill Caiazzi (2024-present): Estrogen signaling in the brain and its impact on peripheral tumor growth